Search Results - "Illiano, Michela"
-
1
Oxidative Stress and Cellular Response to Doxorubicin: A Common Factor in the Complex Milieu of Anthracycline Cardiotoxicity
Published in Oxidative medicine and cellular longevity (01-01-2017)“…The production of reactive species is a core of the redox cycling profile of anthracyclines. However, these molecular characteristics can be viewed as a…”
Get full text
Journal Article -
2
Targeting CREB in Cancer Therapy: A Key Candidate or One of Many? An Update
Published in Cancers (28-10-2020)“…Intratumor heterogeneity (ITH) is considered the major disorienting factor in cancer treatment. As a result of stochastic genetic and epigenetic alterations,…”
Get full text
Journal Article -
3
Forskolin improves sensitivity to doxorubicin of triple negative breast cancer cells via Protein Kinase A-mediated ERK1/2 inhibition
Published in Biochemical pharmacology (01-06-2018)“…[Display omitted] Triple negative breast cancer (TNBC) is an invasive, metastatic, highly aggressive tumor. Cytotoxic chemotherapy represents the current…”
Get full text
Journal Article -
4
Silica/Polyethylene Glycol Hybrid Materials Prepared by a Sol-Gel Method and Containing Chlorogenic Acid
Published in Molecules (Basel, Switzerland) (25-09-2018)“…Chlorogenic acid (CGA) is a very common dietary polyphenolic compound. CGA is becoming very attractive due to its potential use as preventive and therapeutic…”
Get full text
Journal Article -
5
Inorganic Phosphate Prevents Erk1/2 and Stat3 Activation and Improves Sensitivity to Doxorubicin of MDA-MB-231 Breast Cancer Cells
Published in Molecules (Basel, Switzerland) (01-09-2015)“…Due to its expression profile, triple-negative breast cancer (TNBC) is refractory to the most effective targeted therapies available for breast cancer…”
Get full text
Journal Article -
6
The KDM Inhibitor GSKJ4 Triggers CREB Downregulation via a Protein Kinase A and Proteasome-Dependent Mechanism in Human Acute Myeloid Leukemia Cells
Published in Frontiers in oncology (05-06-2020)“…Acute myeloid leukemia (AML) is a progressive hematopoietic-derived cancer arising from stepwise genetic mutations of the myeloid lineage. cAMP response…”
Get full text
Journal Article -
7
Forskolin Sensitizes Human Acute Myeloid Leukemia Cells to H3K27me2/3 Demethylases GSKJ4 Inhibitor via Protein Kinase A
Published in Frontiers in pharmacology (20-07-2018)“…Acute myeloid leukemia (AML) is an aggressive hematological malignancy occurring very often in older adults, with poor prognosis depending on both rapid…”
Get full text
Journal Article -
8
Forskolin sensitizes pancreatic cancer cells to gemcitabine via Stat3 and Erk1/2 inhibition
Published in AIMS molecular science (01-01-2017)“…Cytotoxic chemotherapy, including gemcitabine-based regimens, represents the mainstay of treatment for locally advanced and metastatic pancreatic cancer…”
Get full text
Journal Article -
9
The Natural cAMP Elevating Compound Forskolin in Cancer Therapy: Is It Time?
Published in Journal of cellular physiology (01-05-2017)“…Cancer is a major public health problem and the second leading cause of mortality around the world. Although continuous advances in the science of oncology and…”
Get full text
Journal Article -
10
Chlorogenic acid activates ERK1/2 and inhibits proliferation of osteosarcoma cells
Published in Journal of cellular physiology (01-04-2020)“…Osteosarcoma (OS) is a very aggressive metastatic pediatric and adolescent tumor. Due to its recurrent development of chemotherapy resistance, clinical outcome…”
Get full text
Journal Article -
11
S-Adenosylmethionine Affects ERK1/2 and Stat3 Pathways and Induces Apotosis in Osteosarcoma Cells
Published in Journal of cellular physiology (01-02-2016)“…Osteosarcoma is a very aggressive bone tumor. Its clinical outcome remains discouraging despite intensive surgery, radiotherapy, and chemotherapy. Thus, novel…”
Get full text
Journal Article -
12
Adiponectin down-regulates CREB and inhibits proliferation of A549 lung cancer cells
Published in Pulmonary pharmacology & therapeutics (01-08-2017)“…Adipokines are known to play a relevant role in a number of cancer related molecular pathways. Adiponectin is a major adipokine with anti-inflammatory and…”
Get full text
Journal Article -
13
AdipoRon Affects Cell Cycle Progression and Inhibits Proliferation in Human Osteosarcoma Cells
Published in Journal of oncology (2020)“…AdipoRon (AdipoR) is the first synthetic molecule acting as a selective and potent adiponectin receptor agonist. Recently, the possible pharmacological use of…”
Get full text
Journal Article -
14
Chemical analysis and anti-proliferative activity of Campania Thymus Vulgaris essential oil
Published in The Journal of essential oil research (02-11-2017)“…In this study, the potential antitumor activity of an essential oil (EO) obtained from Thymus vulgaris L. plants cultivated in Campania (Southern Italy) was…”
Get full text
Journal Article -
15
The Influence of the Polymer Amount on the Biological Properties of PCL/ZrO₂ Hybrid Materials Synthesized via Sol-Gel Technique
Published in Materials (17-10-2017)“…Organic/inorganic hybrid materials are attracting considerable attention in the biomedical area. The sol-gel process provides a convenient way to produce many…”
Get full text
Journal Article -
16
Targeting protein kinase A in cancer therapy: an update
Published in EXCLI journal (01-01-2014)“…Protein Kinase A (PKA) is a well known member of the serine-threonin protein kinase superfamily. PKA, also known as cAMP-dependent protein kinase, is a…”
Get full text
Journal Article