Search Results - "Illes, P."

Astrocytes and major depression: The purinergic avenue by Zhao, Y.F., Verkhratsky, A., Tang, Y., Illes, P.

“…Major depressive disorder (MDD) is one of the most prevalent psychiatric illnesses worldwide which impairs the social functioning of the afflicted patients…”
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Involvement of P2 receptors in the growth and survival of neurons in the CNS by Franke, Heike, Illes, Peter

“…Extracellular adenosine 5'-triphosphate (ATP) has been recognized as a ubiquitous, unstable signalling molecule, acting as a fast neurotransmitter and…”
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A comparative analysis of the activity of ligands acting at P2X and P2Y receptor subtypes in models of neuropathic, acute and inflammatory pain by Andó, RD, Méhész, B, Gyires, K, Illes, P, Sperlágh, B

“…Background and purpose:  This study was undertaken to compare the analgesic activity of antagonists acting at P2X1, P2X7, and P2Y12 receptors and agonists…”
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P2 receptors and neuronal injury by Franke, Heike, Krügel, Ute, Illes, Peter

“…Extracellular adenosine 5'-triphosphate (ATP) was proposed to be an activity-dependent signaling molecule that regulates glia-glia and glia-neuron…”
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Increase of intracellular Ca2+ by P2X and P2Y receptor-subtypes in cultured cortical astroglia of the rat by Fischer, W, Appelt, K, Grohmann, M, Franke, H, Nörenberg, W, Illes, P

“…Abstract Astrocytes express purinergic receptors that are involved in glial–neuronal cell communication. Experiments were conducted to characterize the…”
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Electrophysiological classification of P2X7 receptors in rat cultured neocortical astroglia by Nörenberg, W, Schunk, J, Fischer, W, Sobottka, H, Riedel, T, Oliveira, JF, Franke, H, Illes, P

“…Background and purpose:  P2X7 receptors are ATP‐gated cation channels mediating important functions in microglial cells, such as the release of cytokines and…”
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Endocytosis and vesicle trafficking during tip growth of root hairs by Ovecka, M, Lang, I, Baluska, F, Ismail, A, Illes, P, Lichtscheidl, I.K

“…The directional elongation of root hairs, "tip growth", depends on the coordinated and highly regulated trafficking of vesicles which fill the tip cytoplasm…”
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P2X Receptors and Nociception by Chizh, B A, Illes, P

“…The potential importance for nociception of P2X receptors, the ionotropic receptors activated by ATP, is underscored by the variety of pain states in which…”
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Different effects of aluminum on the actin cytoskeleton and brefeldin A-sensitive vesicle recycling in root apex cells of two maize varieties differing in root elongation rate and aluminum tolerance by Amenos, M.(Universitaet Bonn (Germany)), Corrales, I, Poschenrieder, C, Illes, P, Baluska, F, Barcelo, J

“…A relationship between aluminum (Al) toxicity, endocytosis, endosomes and vesicle recycling in the root transition zone has recently been demonstrated. Here…”
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Conformational flexibility of the agonist binding jaw of the human P2X3 receptor is a prerequisite for channel opening by Kowalski, M, Hausmann, R, Dopychai, A, Grohmann, M, Franke, H, Nieber, K, Schmalzing, G, Illes, P, Riedel, T

“…Background and Purpose It is assumed that ATP induces closure of the binding jaw of ligand‐gated P2X receptors, which eventually results in the opening of the…”
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P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo by Franke, H., Sauer, C., Rudolph, C., Krügel, U., Hengstler, J. G., Illes, P.

“…ATP acts as a growth factor as well as a toxic agent by stimulating P2 receptors. The P2 receptor‐activated signaling cascades mediating cellular growth and…”
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Neuronal P2X receptors: localisation and functional properties by Nörenberg, W, Illes, P

“…ATP is a co-transmitter in the central and peripheral nervous system. Extracellular ATP exerts its effects via ionotropic (P2X), as well as metabotropic…”
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Metabotropic P2Y receptors inhibit P2X 3 receptor‐channels via G protein‐dependent facilitation of their desensitization by Gerevich, Z, Zadori, Z, Müller, C, Wirkner, K, Schröder, W, Rubini, P, Illes, P

“…Background and purpose: The aim of the present study was to investigate whether the endogenous metabotropic P2Y receptors modulate ionotropic P2X 3…”
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Differential effects of P2Y1 deletion on glial activation and survival of photoreceptors and amacrine cells in the ischemic mouse retina by Pannicke, T, Frommherz, I, Biedermann, B, Wagner, L, Sauer, K, Ulbricht, E, Härtig, W, Krügel, U, Ueberham, U, Arendt, T, Illes, P, Bringmann, A, Reichenbach, A, Grosche, A

“…Gliosis of retinal Müller glial cells may have both beneficial and detrimental effects on neurons. To investigate the role of purinergic signaling in…”
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Purine ionotropic (P2X) receptors by Köles, L, Fürst, S, Illes, P

“…Purinergic signaling is involved in the proper functioning of virtually all organs of the body. Although in some cases purines have a major influence on…”
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P2 receptor expression in the dopaminergic system of the rat brain during development by Heine, C, Wegner, A, Grosche, J, Allgaier, C, Illes, P, Franke, H

“…Abstract Extracellular ATP facilitates the release of dopamine via P2 receptor activation in parts of the mesolimbic system. To characterize P2X/Y receptor…”
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The unusual state-dependent affinity of P2X3 receptors can be explained by an allosteric two-open-state model by Karoly, R, Mike, A, Illes, P, Gerevich, Z

“…High-affinity desensitization (HAD) by nanomolar agonists was described to shape the ability of P2X(3) receptors for mediating pain sensation. These receptors…”
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Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus by Sperlágh, B, Zsilla, G, Baranyi, M, Illes, P, Vizi, E.S

“…Abstract The aim of the present study was to explore whether endogenous activation of different purine receptors by ATP and adenosine contributes to or…”
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Neuroprotective effects of the P2 receptor antagonist PPADS on focal cerebral ischaemia-induced injury in rats by Lämmer, A., Günther, A., Beck, A., Krügel, U., Kittner, H., Schneider, D., Illes, P., Franke, H.

“…After acute injury of the central nervous system extracellular adenosine 5′‐triphosphate (ATP) can reach high concentrations as a result of cell damage and…”
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Co-transmitter function of ATP in central catecholaminergic neurons of the rat by Poelchen, W, Sieler, D, Wirkner, K, Illes, P

“…Intracellular recordings were made in a mid-pontine slice preparation of the rat brain containing the nucleus locus coeruleus. Focal electrical stimulation…”
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