Search Results - "Illera, Nuria"
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Differential Features between Chronic Skin Inflammatory Diseases Revealed in Skin-Humanized Psoriasis and Atopic Dermatitis Mouse Models
Published in Journal of investigative dermatology (01-01-2016)“…Psoriasis and atopic dermatitis are chronic and relapsing inflammatory diseases of the skin affecting a large number of patients worldwide. Psoriasis is…”
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Targeted silencing of DEFB4 in a bioengineered skin-humanized mouse model for psoriasis: development of siRNA SECosome-based novel therapies
Published in Experimental dermatology (01-03-2014)“…Psoriasis is a complex inflammatory skin disease that presents a wide variety of clinical manifestations. Human β defensin‐2 (hBD‐2) is highly up‐regulated in…”
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3
Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells
Published in Molecular therapy. Nucleic acids (01-06-2018)“…Recessive dystrophic epidermolysis bullosa is a severe skin fragility disease caused by loss of functional type VII collagen at the dermal-epidermal junction…”
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4
Beneficial Effect of Systemic Allogeneic Adipose Derived Mesenchymal Cells on the Clinical, Inflammatory and Immunologic Status of a Patient With Recessive Dystrophic Epidermolysis Bullosa: A Case Report
Published in Frontiers in medicine (26-11-2020)“…Recessive dystrophic epidermolysis bullosa (RDEB) is an incurable inherited mucocutaneous fragility disorder characterized by recurrent blisters, erosions, and…”
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5
A prevalent mutation with founder effect in Spanish Recessive Dystrophic Epidermolysis Bullosa families
Published in BMC genetics (29-09-2010)“…Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a genodermatosis caused by more than 500 different mutations in the COL7A1 gene and characterized by…”
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FPR2 DNA Aptamers for Targeted Therapy of Wound Repair
Published in Journal of investigative dermatology (01-08-2022)“…Chronic wounds represent a major health problem worldwide. Some of the available therapies based on recombinant proteins usually fail owing to the hostile…”
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Evaluation of Systemic Gentamicin as Translational Readthrough Therapy for a Patient With Epidermolysis Bullosa Simplex With Muscular Dystrophy Owing to PLEC1 Pathogenic Nonsense Variants
Published in JAMA dermatology (Chicago, Ill.) (01-04-2022)“…Epidermolysis bullosa simplex with muscular dystrophy (EBS-MD) is an autosomal recessive disorder caused by pathogenic variants in PLEC1, which encodes…”
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Gluten-sensitive enteropathy in recessive dystrophic epidermolysis bullosa
Published in British journal of dermatology (1951) (16-11-2023)“…Recessive dystrophic epidermolysis bullosa (RDEB) is a blistering genodermatosis due to biallelic loss-of-function variants in the type VII collagen (C7) gene…”
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Unveiling the value of C‐reactive protein as a severity biomarker and the IL4/IL13 pathway as a therapeutic target in recessive dystrophic epidermolysis bullosa: A multiparametric cross‐sectional study
Published in Experimental dermatology (01-08-2024)“…Patients with recessive dystrophic epidermolysis bullosa (RDEB) experience numerous complications, which are exacerbated by inflammatory dysregulation and…”
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Development of a Bioengineered Skin-Humanized Mouse Model for Psoriasis: Dissecting Epidermal-Lymphocyte Interacting Pathways
Published in The American journal of pathology (01-12-2010)“…Over the past few years, whole skin xenotransplantation models that mimic different aspects of psoriasis have become available. However, these models are…”
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11
In Vivo Assessment of Acute UVB Responses in Normal and Xeroderma Pigmentosum (XP-C) Skin-Humanized Mouse Models
Published in The American journal of pathology (01-08-2010)“…In vivo studies of UVB effects on human skin are precluded by ethical and technical arguments on volunteers and inconceivable in cancer-prone patients such as…”
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12
The regenerative potential of fibroblasts in a new diabetes-induced delayed humanised wound healing model
Published in Experimental dermatology (01-03-2013)“…Cutaneous diabetic wounds greatly affect the quality of life of patients, causing a substantial economic impact on the healthcare system. The limited clinical…”
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13
Targeted silencing of DEFB 4 in a bioengineered skin‐humanized mouse model for psoriasis: development of si RNA SEC osome‐based novel therapies
Published in Experimental dermatology (01-03-2014)“…Abstract Psoriasis is a complex inflammatory skin disease that presents a wide variety of clinical manifestations. Human β defensin‐2 ( hBD ‐2) is highly…”
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Journal Article -
14
Development of a Bioengineered Skin-Humanized Mouse Model for Psoriasis
Published in The American journal of pathology (01-12-2010)“…Over the past few years, whole skin xenotransplantation models that mimic different aspects of psoriasis have become available. However, these models are…”
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Journal Article -
15
Beneficial Effect of Systemic Allogeneic Adipose Derived Mesenchymal Cells on the Clinical, Inflammatory and Immunologic Status of a Patient With Recessive Dystrophic Epidermolysis Bullosa: A Case Report
Published in Frontiers in medicine (01-01-2020)“…Recessive dystrophic epidermolysis bullosa (RDEB) is an incurable inherited mucocutaneous fragility disorder characterized by recurrent blisters, erosions, and…”
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Report