Search Results - "Iljin, K"

Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress by Ketola, K, Hilvo, M, Hyötyläinen, T, Vuoristo, A, Ruskeepää, A-L, Orešič, M, Kallioniemi, O, Iljin, K

“…Background: We have shown that a sodium ionophore monensin inhibits prostate cancer cell growth. A structurally related compound to monensin, salinomycin, was…”
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Layered material platform for surface plasmon resonance biosensing by Wu, F., Thomas, P. A., Kravets, V. G., Arola, H. O., Soikkeli, M., Iljin, K., Kim, G., Kim, M., Shin, H. S., Andreeva, D. V., Neumann, C., Küllmer, M., Turchanin, A., De Fazio, D., Balci, O., Babenko, V., Luo, B., Goykhman, I., Hofmann, S., Ferrari, A. C., Novoselov, K. S., Grigorenko, A. N.

“…Plasmonic biosensing has emerged as the most sensitive label-free technique to detect various molecular species in solutions and has already proved crucial in…”
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PO-461 Mitochondria-mediated anticancer effect of diphenyleneiodonium chloride (DPI) in aggressive neuroblastoma is regulated by MYCN by Marcone, S, Iljin, K, Dempsey, E, Fey, D, Duffy, D, Westermann, F, Kolch, W, Halasz, M

“…IntroductionNeuroblastoma (NB) is the most common solid tumour in children under the age of five and it is responsible for 15% of paediatric cancer deaths…”
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Bmx Tyrosine Kinase Has a Redundant Function Downstream of Angiopoietin and Vascular Endothelial Growth Factor Receptors in Arterial Endothelium by Rajantie, Iiro, Ekman, Niklas, Iljin, Kristiina, Arighi, Elena, Gunji, Yuji, Kaukonen, Jaakko, Palotie, Aarno, Dewerchin, Mieke, Carmeliet, Peter, Alitalo, Kari

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234 Drugs with known pharmacological profiles, such as monensin, disulfiram and salinomycin, show cancer-selective inhibition of prostate cancer cell growth by increasing oxidative stress by Ketola, K, Vainio, P, Fey, V, Kohonen, P, Kallioniemi, O, Iljin, K

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Expression of mammary derived growth inhibitor (MDGI) results in phenotypic reversal in breast cancer by Nevo, J, Mattila, E, Pellinen, T, Yamamoto, D.L, Sara, H, Iljin, K, Kallioniemi, O, Bono, P, Wärri, A, Ivaska, J

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High-Throughput Cell-Based Screening of 4910 Known Drugs and Drug-like Small Molecules Identifies Disulfiram as an Inhibitor of Prostate Cancer Cell Growth by IIJIN, Kristiina, KETOLA, Kirsi, VAINIO, Paula, HALONEN, Pasi, KOHONEN, Pekka, FEY, Vidal, GRAFSTRÖM, Roland C, PERÄLÄ, Merja, KALLIONIEMI, Olli

“…Purpose: To identify novel therapeutic opportunities for patients with prostate cancer, we applied high-throughput screening to systematically explore most…”
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Correction to “Integration of Metabolomics and Expression of Glycerol-3-phosphate Acyltransferase (GPAM) in Breast CancerLink to Patient Survival, Hormone Receptor Status, and Metabolic Profiling” by Brockmöller, Scarlet F., Bucher, Elmar, Müller, Berit M., Budczies, Jan, Hilvo, Mika, Griffin, Julian L., Orešič, Matej, Kallioniemi, Olli, Iljin, Kristiina, Loibl, Sibylle, Darb-Esfahani, Silvia, Sinn, Bruno V., Klauschen, Frederick, Prinzler, Judith, Bangemann, Nikola, Ismaeel, Fakher, Fiehn, Oliver, Dietel, Manfred, Denkert, Carsten

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c-Jun N-Terminal Kinase Phosphorylation of MARCKSL1 Determines Actin Stability and Migration in Neurons and in Cancer Cells by Björkblom, Benny, Padzik, Artur, Mohammad, Hasan, Westerlund, Nina, Komulainen, Emilia, Hollos, Patrik, Parviainen, Lotta, Papageorgiou, Anastassios C., Iljin, Kristiina, Kallioniemi, Olli, Kallajoki, Markku, Courtney, Michael J., Mågård, Mats, James, Peter, Coffey, Eleanor T.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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FHOD1, a formin upregulated in epithelial-mesenchymal transition, participates in cancer cell migration and invasion by Gardberg, Maria, Kaipio, Katja, Lehtinen, Laura, Mikkonen, Piia, Heuser, Vanina D, Talvinen, Kati, Iljin, Kristiina, Kampf, Caroline, Uhlen, Mathias, Grénman, Reidar, Koivisto, Mari, Carpén, Olli

“…Cancer cells can obtain their ability to invade and metastasise by undergoing epithelial-to-mesenchymal transition (EMT). Exploiting this mechanism of cellular…”
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Tie receptors: new modulators of angiogenic and lymphangiogenic responses by Alitalo, Kari, Jones, Nina, Iljin, Kristiina, Dumont, Daniel J

“…Angiogenesis is required for normal embryonic vascular development and aberrant angiogenesis contributes to several diseases, including cancer, diabetes and…”
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Androgen receptor‐interacting protein HSPBAP1 facilitates growth of prostate cancer cells in androgen‐deficient conditions by Saeed, Khalid, Östling, Päivi, Björkman, Mari, Mirtti, Tuomas, Alanen, Kalle, Vesterinen, Tiina, Sankila, Anna, Lundin, Johan, Lundin, Mikael, Rannikko, Antti, Nordling, Stig, Mpindi, John‐Patrick, Kohonen, Pekka, Iljin, Kristiina, Kallioniemi, Olli, Rantala, Juha K.

“…Hormonal therapies targeting androgen receptor (AR) are effective in prostate cancer (PCa), but often the cancers progress to fatal castrate‐resistant disease…”
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Differentiation-Promoting Culture of Competent and Noncompetent Keratinocytes Identifies Biomarkers for Head and Neck Cancer by Ceder, Rebecca, Haig, Ylva, Merne, Marina, Hansson, Annette, Zheng, Xi, Roberg, Karin, Nees, Matthias, Iljin, Kristiina, Bloor, Balvinder K, Morgan, Peter R, Fadeel, Bengt, Grafström, Roland C

“…Aberrant contact-inhibited proliferation and differentiation induction couple with tumor severity, albeit with an imprecise association with prognosis…”
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PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial‐mesenchymal transition in cultured breast cancer cells by Lehtinen, Laura, Vainio, Paula, Wikman, Harriet, Huhtala, Heini, Mueller, Volkmar, Kallioniemi, Anne, Pantel, Klaus, Kronqvist, Pauliina, Kallioniemi, Olli, Carpèn, Olli, Iljin, Kristiina

“…Breast cancer is the leading cause of cancer‐related deaths in women due to distinct cancer subtypes associated with early recurrence and aggressive metastatic…”
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Integrative functional genomics analysis of sustained polyploidyphenotypes in breast cancer cells identifies an oncogenic profile for GINS2 by Rantala, J K, Lehtinen, L, Aaltola, A-R, Laasola, P, Edgren, H, Kilpinen, S, Saviranta, P, Iljin, K, Kallioniemi, O

“…Aneuploidy is among the most obvious differences between normal and cancer cells. However, mechanisms contributing to development and maintenance of aneuploid…”
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Endothelial cells genetically selected from differentiating mouse embryonic stem cells incorporate at sites of neovascularization in vivo by Marchetti, Sandrine, Gimond, Clotilde, Iljin, Kristiina, Bourcier, Christine, Alitalo, Kari, Pouysségur, Jacques, Pagès, Gilles

“…Large scale purification of endothelial cells is of great interest as it could improve tissue transplantation, reperfusion of ischemic tissues and treatment of…”
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A fluorescent Tie1 reporter allows monitoring of vascular development and endothelial cell isolation from transgenic mouse embryos by Iljin, Kristiina, Petrova, Tatiana V., Veikkola, Tanja, Kumar, Vijay, Poutanen, Matti, Alitalo, Kari

“…Tie1 is an endothelial receptor tyrosine kinase essential for development and maintenance of the vascular system. Here we report generation of transgenic mice…”
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Role of Ets factors in the activity and endothelial cell specificity of the mouse Tie gene promoter by ILJIN, KRISTIINA, DUBE, ANTOINISE, KONTUSAARI, SIRPA, KORHONEN, JAANA, LAHTINEN, ISTO, OETTGEN, PETER, ALITALO, KARI

“…ABSTRACT The Tie gene encodes an endothelial cell receptor tyrosine kinase necessary for normal vascular development. The Tie gene promoter targets expression…”
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VEGFR3 gene structure, regulatory region, and sequence polymorphisms by Iljin, K, Karkkainen, M J, Lawrence, E C, Kimak, M A, Uutela, M, Taipale, J, Pajusola, K, Alhonen, L, Halmekytö, M, Finegold, D N, Ferrell, R E, Alitalo, K

“…Vascular endothelial growth factor receptor 3 (VEGFR-3) is required for cardiovascular development during embryogenesis. In adults, this receptor is expressed…”
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