Search Results - "Ilina, Tatiana"

Interplay between protease and reverse transcriptase dimerization in a model HIV‐1 polyprotein by Chagas, Brisa Caroline Alves, Zhou, Xiaohong, Guerrero, Michel, Ilina, Tatiana V., Ishima, Rieko

“…The Gag‐Pol polyprotein in human immunodeficiency virus type I (HIV‐1) encodes enzymes that are essential for virus replication: protease (PR), reverse…”
Get full text

The HIV-1 protein Nef activates the Tec family kinase Btk by stabilizing an intermolecular SH3-SH2 domain interaction by Aryal, Manish, Lin, David, Regan, Kiera, Du, Shoucheng, Shi, Haibin, Alvarado, John J, Ilina, Tatiana V, Andreotti, Amy H, Smithgall, Thomas E

“…The Nef protein produced by the viruses HIV-1 and SIV drives efficient viral replication partially by inducing constitutive activation of host cell tyrosine…”
Get more information

A synergy of activity, stability, and inhibitor‐interaction of HIV‐1 protease mutants evolved under drug‐pressure by Khan, Shahid N., Persons, John D., Guerrero, Michel, Ilina, Tatiana V., Oda, Masayuki, Ishima, Rieko

“…A clinically‐relevant, drug‐resistant mutant of HIV‐1 protease (PR), termed Flap+(I54V) and containing L10I, G48V, I54V and V82A mutations, is known to produce…”
Get full text

Development of Human Immunodeficiency Virus Type 1 Resistance to 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine Starting with Wild-Type or Nucleoside Reverse Transcriptase Inhibitor-Resistant Strains by Cilento, Maria E, Reeve, Aaron B, Michailidis, Eleftherios, Ilina, Tatiana V, Nagy, Eva, Mitsuya, Hiroaki, Parniak, Michael A, Tedbury, Philip R, Sarafianos, Stefan G

“…4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA, MK-8591, islatravir) is a nucleoside reverse transcriptase translocation inhibitor (NRTTI) with exceptional…”
Get full text

The reduced form of the antibody CH2 domain by Xi, Zhaoyong, Liu, Xianglei, Lin, Rui, Persons, John D., Ilina, Tatiana V., Li, Wei, Dimitrov, Dimiter S., Ishima, Rieko

“…Among the immunoglobulin domains, the CH2 domain has the lowest thermal stability, which also depends on amino acid sequence and buffer conditions. To further…”
Get full text

Large Multidomain Protein NMR: HIV-1 Reverse Transcriptase Precursor in Solution by Ilina, Tatiana V, Xi, Zhaoyong, Brosenitsch, Teresa, Sluis-Cremer, Nicolas, Ishima, Rieko

“…NMR studies of large proteins, over 100 kDa, in solution are technically challenging and, therefore, of considerable interest in the biophysics field. The…”
Get full text

Ferromagnetic phase nucleation and its growth evolution in FeRh thin films by Komlev, Aleksei S., Karpenkov, Dmitriy Y., Kiselev, Dmitry A., Ilina, Tatiana S., Chirkova, Alisa, Gimaev, Radel R., Usami, Takamasa, Taniyama, Tomoyasu, Zverev, Vladimir I., Perov, Nikolai S.

“…•The relaxation of magnetization in thin FeRh films has been studied during phase transition.•A phenomenological model that describes the evolution of the…”
Get full text

Relative domain orientation of the L289K HIV‐1 reverse transcriptase monomer by Xi, Zhaoyong, Ilina, Tatiana V., Guerrero, Michel, Fan, Lixin, Sluis‐Cremer, Nicolas, Wang, Yun‐Xing, Ishima, Rieko

“…HIV‐1 reverse transcriptase (RT) is a heterodimer comprised p66 and p51 subunits (p66/p51). Several single amino acid substitutions in RT, including L289K,…”
Get full text

Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate by Sun, Zehua, Chu, Xiaojie, Adams, Cynthia, Ilina, Tatiana V., Guerrero, Michel, Lin, Guowu, Chen, Chuan, Jelev, Dontcho, Ishima, Rieko, Li, Wei, Mellors, John W., Calero, Guillermo, Dimitrov, Dimiter S.

“…Mesothelin (MSLN) has been a validated tumor-associated antigen target for several solid tumors for over a decade, making it an attractive option for…”
Get full text

Effect of Lysyl–tRNA Synthetase on the Maturation of HIV‑1 Reverse Transcriptase by Ilina, Tatiana V, Slack, Ryan L, Guerrero, Michel, Ishima, Rieko

“…In human immunodeficiency virus-1 (HIV-1), reverse transcriptase (RT) is encoded as a 66 kDa protein, p66, in the Gag-Pol polyprotein. This protein is…”
Get full text

Effect of Composition and Surface Microstructure in Self-Polarized Ferroelectric Polymer Films on the Magnitude of the Surface Potential by Kochervinskii, Valentin V, Buryanskaya, Evgeniya L, Makeev, Mstislav O, Mikhalev, Pavel A, Kiselev, Dmitry A, Ilina, Tatiana S, Lokshin, Boris V, Zvyagina, Aleksandra I, Kirakosyan, Gayane A

“…The values of the surface potentials of two sides of films of polyvinylidene fluoride, and its copolymers with tetrafluoroethylene and hexafluoropropylene,…”
Get full text

The effect of crystal polymorphism of ferroelectric copolymer vinylidene fluoride‐hexafluoropropylene on its high‐voltage polarization by Kochervinskii, Valentin V., Malyshkina, Inna A., Kiselev, Dmitry A., Ilina, Tatiana S., Kozlova, Nina V., Shmakova, Nina A., Korlyukov, Alexander A., Gradova, Margaret A., Bedin, Sergey A.

“…Dielectric response of vinylidene fluoride‐hexafluoropropylene copolymer, crystallized in different polymorph modifications, to a high‐voltage electric field…”
Get full text

Effect of tRNA on the Maturation of HIV-1 Reverse Transcriptase by Ilina, Tatiana V., Slack, Ryan L., Elder, John H., Sarafianos, Stefan G., Parniak, Michael A., Ishima, Rieko

“…The mature HIV-1 reverse transcriptase is a heterodimer that comprises 66 kDa (p66) and 51 kDa (p51) subunits. The latter is formed by HIV-1 protease-catalyzed…”
Get full text

Boosting Magnetoelectric Effect in Polymer-Based Nanocomposites by Omelyanchik, Alexander, Antipova, Valentina, Gritsenko, Christina, Kolesnikova, Valeria, Murzin, Dmitry, Han, Yilin, Turutin, Andrei V, Kubasov, Ilya V, Kislyuk, Alexander M, Ilina, Tatiana S, Kiselev, Dmitry A, Voronova, Marina I, Malinkovich, Mikhail D, Parkhomenko, Yuriy N, Silibin, Maxim, Kozlova, Elena N, Peddis, Davide, Levada, Kateryna, Makarova, Liudmila, Amirov, Abdulkarim, Rodionova, Valeria

“…Polymer-based magnetoelectric composite materials have attracted a lot of attention due to their high potential in various types of applications as magnetic…”
Get full text

Retroviral RNase H: Structure, mechanism, and inhibition by Ilina, Tatiana V, Brosenitsch, Teresa, Sluis-Cremer, Nicolas, Ishima, Rieko

“…All retroviruses encode the enzyme, reverse transcriptase (RT), which is involved in the conversion of the single-stranded viral RNA genome into…”
Get full text

Conformational Changes in HIV-1 Reverse Transcriptase that Facilitate Its Maturation by Slack, Ryan L., Ilina, Tatiana V., Xi, Zhaoyong, Giacobbi, Nicholas S., Kawai, Gota, Parniak, Michael A., Sarafianos, Stefan G., Sluis Cremer, Nicolas, Ishima, Rieko

“…HIV-1 reverse transcriptase (RT) is translated as part of the Gag-Pol polyprotein that is proteolytically processed by HIV-1 protease (PR) to finally become a…”
Get full text

Inhibitors of HIV‑1 Nef-Mediated Activation of the Myeloid Src-Family Kinase Hck Block HIV‑1 Replication in Macrophages and Disrupt MHC‑I Downregulation by Emert-Sedlak, Lori A, Moukha-Chafiq, Omar, Shi, Haibin, Du, Shoucheng, Alvarado, John J, Pathak, Vibha, Tanner, Samuel G, Hunter, Robert N, Nebane, Miranda, Chen, Li, Ilina, Tatiana V, Ishima, Rieko, Zhang, Sixue, Kuzmichev, Yury V, Wonderlich, Elizabeth R, Schader, Susan M, Augelli-Szafran, Corinne E, Ptak, Roger G, Smithgall, Thomas E

“…HIV-1 Nef is an attractive target for antiretroviral drug discovery because of its role in promoting HIV-1 infectivity, replication, and host immune system…”
Get full text

Strontium Ferromolybdate-Based Magnetic Tunnel Junctions by Suchaneck, Gunnar, Artiukh, Evgenii, Sobolev, Nikolai A., Telesh, Eugene, Kalanda, Nikolay, Kiselev, Dmitry A., Ilina, Tatiana S., Gerlach, Gerald

“…Thin-film strontium ferromolybdate is a promising material for applications in room-temperature magnetic tunnel junction devices. These are spin-based,…”
Get full text

Synthesis and Properties of 2′-Deoxy-2′,4′-difluoroarabinose-Modified Nucleic Acids by Martínez-Montero, Saúl, Deleavey, Glen F, Dierker-Viik, Arden, Lindovska, Petra, Ilina, Tatiana, Portella, Guillem, Orozco, Modesto, Parniak, Michael A, González, Carlos, Damha, Masad J

“…We report the synthesis, thermal stability, and RNase H substrate activity of 2′-deoxy-2′,4′-difluoroarabino-modified nucleic acids…”
Get full text

Synthesis of silicon-carbon films by induction-assisted plasma-chemical deposition by Temirov, Alexander A., Kubasov, Ilya V., Turutin, Andrei V., Ilina, Tatiana S., Kislyuk, Alexander M., Kiselev, Dmitry A., Skryleva, Elena A., Sobolev, Nikolai A., Salimon, Igor A., Batrameev, Nikolai V., Malinkovich, Mikhail D., Parkhomenko, Yuri N.

“…Silicon-carbon films are of great interest as diamond-like materials combining unique properties, e.g. high hardness, adhesion to a wide range of materials,…”
Get full text