Search Results - "Ilina, Elena I."
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A hereditary spastic paraplegia mouse model supports a role of ZFYVE26/SPASTIZIN for the endolysosomal system
Published in PLoS genetics (01-12-2013)“…Hereditary spastic paraplegias (HSPs) are characterized by progressive weakness and spasticity of the legs because of the degeneration of cortical motoneuron…”
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Impact of Docetaxel on blood-brain barrier function and formation of breast cancer brain metastases
Published in Journal of experimental & clinical cancer research (29-10-2019)“…Breast cancer (BC) is the most frequent malignant tumor in females and the 2nd most common cause of brain metastasis (BM), that are associated with a fatal…”
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Prediction and verification of glycosyltransferase activity by bioinformatics analysis and protein engineering
Published in STAR protocols (17-03-2023)“…A significant number of proteins are annotated as functionally uncharacterized proteins. Within this protocol, we describe how to use protein family multiple…”
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Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration
Published in iScience (18-02-2022)“…Glioblastoma (GBM) is the most aggressive primary brain tumor characterized by infiltrative growth of malignant glioma cells into the surrounding brain…”
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Dominant-negative effects of KCNQ2 mutations are associated with epileptic encephalopathy
Published in Annals of neurology (01-03-2014)“…Objective Mutations in KCNQ2 and KCNQ3, encoding the voltage‐gated potassium channels KV7.2 and KV7.3, are known to cause benign familial neonatal seizures…”
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TGF‐β activates pericytes via induction of the epithelial‐to‐mesenchymal transition protein SLUG in glioblastoma
Published in Neuropathology and applied neurobiology (01-10-2021)“…Aims In primary central nervous system tumours, epithelial‐to‐mesenchymal transition (EMT) gene expression is associated with increased malignancy. However, it…”
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VERA: agent-based modeling transmission of antibiotic resistance between human pathogens and gut microbiota
Published in Bioinformatics (01-10-2019)“…Abstract Motivation The resistance of bacterial pathogens to antibiotics is one of the most important issues of modern health care. The human microbiota can…”
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Mistletoe-Based Drugs Work in Synergy with Radio-Chemotherapy in the Treatment of Glioma In Vitro and In Vivo in Glioblastoma Bearing Mice
Published in Evidence-based complementary and alternative medicine (01-01-2019)“…Background. Extracts from Viscum album L. (VE) are used in the complementary cancer therapy in Europe for decades. VE contain several compounds like the…”
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Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors
Published in International journal of oncology (01-08-2017)“…Glioblastoma (GBM), the most frequent and aggressive malignant primary brain tumor, is characterized by a highly invasive growth. In our previous study we…”
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Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas
Published in Oncotarget (12-04-2016)“…Recently, the conserved intracellular digestion mechanism 'autophagy' has been considered to be involved in early tumorigenesis and its blockade proposed as an…”
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Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux
Published in Oncotarget (15-09-2017)“…Carboxypeptidase E (CPE) has recently been described as a multifunctional protein that regulates proliferation, migration and survival in several tumor…”
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A Hereditary Spastic Paraplegia Mouse Model Supports a Role of ZFYVE26/SPASTIZIN for the Endolysosomal System: e1003988
Published in PLoS genetics (01-12-2013)“…Hereditary spastic paraplegias (HSPs) are characterized by progressive weakness and spasticity of the legs because of the degeneration of cortical motoneuron…”
Get full text
Journal Article