Search Results - "Ilie, M."
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Comparative study of the PD-L1 status between surgically resected specimens and matched biopsies of NSCLC patients reveal major discordances: a potential issue for anti-PD-L1 therapeutic strategies
Published in Annals of oncology (01-01-2016)“…High expression of programmed death ligand-1 (PD-L1) on tumor cells (TC) and/or on tumor-infiltrating immune cells (IC) is associated with a high response rate…”
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Disorder at the Tips of a Disease-Relevant Aβ42 Amyloid Fibril: A Molecular Dynamics Study
Published in The journal of physical chemistry. B (13-12-2018)“…We present a simulation study of the early events of peptide dissociation from a fibril of the Alzheimer’s Aβ42 peptide. The fibril consists of layers of two…”
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Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes
Published in Oncogene (01-07-2015)“…Tissue inhibitor of metalloproteinases-1 (TIMP-1) recently emerged as a pro-metastatic factor highly associated with poor prognosis in a number of cancers…”
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Bilinear Bäcklund transformation, Lax pair, Painlevé integrability, and different wave structures of a 3D generalized KdV equation
Published in Nonlinear dynamics (01-10-2024)“…The current paper conducts comprehensive research on a 3D generalized Korteweg-de Vries (3D-gKdV) equation describing long-wave behavior in shallow water…”
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Discrepancies between FISH and immunohistochemistry for assessment of the ALK status are associated with ALK ‘borderline’-positive rearrangements or a high copy number: a potential major issue for anti-ALK therapeutic strategies
Published in Annals of oncology (01-01-2015)“…Patients with advanced lung adenocarcinomas expressing ALK rearrangements are highly responsive to crizotinib, a dual ALK/c-MET inhibitor. Immunohistochemistry…”
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ALK-gene rearrangement: a comparative analysis on circulating tumour cells and tumour tissue from patients with lung adenocarcinoma
Published in Annals of oncology (01-11-2012)“…A subgroup of anaplastic lymphoma kinase (ALK)-rearranged lung tumours can respond to ALK inhibitors. Until now, the ALK status in circulating tumour cells…”
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Pitfalls in lung cancer molecular pathology: how to limit them in routine practice?
Published in Current medicinal chemistry (2012)“…New treatment options in advanced non-small cell lung carcinoma (NSCLC) targeting activating epidermal growth factor receptor (EGFR) gene mutations and other…”
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A detailed study on a new (2+1)-dimensional mKdV equation involving the Caputo–Fabrizio time-fractional derivative
Published in Advances in difference equations (06-07-2020)“…The present article aims to present a comprehensive study on a nonlinear time-fractional model involving the Caputo–Fabrizio (CF) derivative. More explicitly,…”
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Is Teachers’ Well-Being Associated with Students’ School Experience? A Meta-analysis of Cross-Sectional Evidence
Published in Educational psychology review (01-03-2023)“…The present contribution reports a systematic review of the literature that analyzed the relationships between teachers’ subjective well-being (SWB) and…”
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Diagnostic value of immunohistochemistry for the detection of the BRAF mutation in primary lung adenocarcinoma Caucasian patients
Published in Annals of oncology (01-03-2013)Get full text
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Clinical value of circulating endothelial cells and of soluble CD146 levels in patients undergoing surgery for non-small cell lung cancer
Published in British journal of cancer (04-03-2014)“…Background: Previous studies indicate that endothelial injury, as demonstrated by the presence of circulating endothelial cells (CECs), may predict clinical…”
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KRAS Mutations in Lung Adenocarcinoma: Molecular and Epidemiological Characteristics, Methods for Detection, and Therapeutic Strategy Perspectives
Published in Current molecular medicine (10-07-2015)“…KRAS mutations are detected in over one third of lung adenocarcinomas, most frequently in Caucasian and smoker patients. The impact of KRAS mutations on lung…”
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Association of combined PD‐L1 expression and tumour‐infiltrating lymphocyte features with survival and treatment outcomes in patients with metastatic melanoma
Published in Journal of the European Academy of Dermatology and Venereology (01-05-2020)“…Background Recent advances obtained with immune checkpoint inhibitors (ICIs) targeting the programmed cell death‐1 (PD‐1) protein have significantly improved…”
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A nonlinear Schrödinger equation describing the polarization mode and its chirped optical solitons
Published in Optical and quantum electronics (01-06-2021)“…A nonlinear Schrödinger equation describing the polarization mode in an optical fiber which involves different physical terms such as quintic nonlinearity,…”
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Diagnostic value of immunohistochemistry for the detection of the BRAFV600E mutation in primary lung adenocarcinoma Caucasian patients
Published in Annals of oncology (01-03-2013)“…Non-small-cell lung carcinoma (NSCLC) patients with a BRAFV600E mutation benefit from targeted therapy. The usefulness of immunohistochemistry (IHC) as an…”
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Simulation Studies of Amyloidogenic Polypeptides and Their Aggregates
Published in Chemical reviews (26-06-2019)“…Amyloids, fibrillar assembly of (poly)peptide chains, are associated with neurodegenerative illnesses such as Alzheimer’s and Parkinson’s diseases, for which…”
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PIXE, ED‐XRF and optical analysis to authenticate the Garvăn gold monetary treasury
Published in Archaeometry (01-06-2021)“…Nowadays the forgery of cultural heritage is on the rise, damaging the patrimony and its cultural value. Objects of value may still be unveiled at various…”
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18FDG PET/CT in the early assessment of non-small cell lung cancer response to immunotherapy: frequency and clinical significance of atypical evolutive patterns
Published in European journal of nuclear medicine and molecular imaging (01-05-2020)“…Purpose This prospective study aimed (1) to assess the non-small cell lung cancer (NSCLC) evolutive patterns to immunotherapy using FDG-PET and (2) to describe…”
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The thyroid gland: a crossroad in inflammation-induced carcinoma? An ongoing debate with new therapeutic potential
Published in Current medicinal chemistry (01-10-2010)“…Chronic infection and inflammation contribute to around 25% of cancer cases worldwide. While a direct link between several types of human malignancies and…”
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