Search Results - "Ilia, G."

Nanodiscs for structural and functional studies of membrane proteins by Denisov, Ilia G, Sligar, Stephen G

“…The use of nanodiscs is substantially fostering structural and functional studies of membrane protein. This Perspective summarizes the recent use of nanodiscs…”
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Nanodiscs in Membrane Biochemistry and Biophysics by Denisov, Ilia G, Sligar, Stephen G

“…Membrane proteins play a most important part in metabolism, signaling, cell motility, transport, development, and many other biochemical and biophysical…”
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Nanodiscs: A toolkit for membrane protein science by Sligar, Stephen G., Denisov, Ilia G.

“…Membrane proteins are involved in numerous vital biological processes, including transport, signal transduction and the enzymes in a variety of metabolic…”
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Leader-Follower Synchronization of Euler-Lagrange Systems With Time-Varying Leader Trajectory and Constrained Discrete-Time Communication by Abdessameud, Abdelkader, Tayebi, Abdelhamid, Polushin, Ilia G.

“…This paper addresses the leader-follower synchronization problem of uncertain networked Euler-Lagrange systems under directed interconnection graphs in the…”
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Spectroscopic studies of the cytochrome P450 reaction mechanisms by Mak, Piotr J., Denisov, Ilia G.

“…The cytochrome P450 monooxygenases (P450s) are thiolate heme proteins that can, often under physiological conditions, catalyze many distinct oxidative…”
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Nanodiscs for the study of membrane proteins by Denisov, Ilia G., Sligar, Stephen G.

“…Nanodiscs represent a versatile tool for studies of membrane proteins and protein-membrane interactions under native-like conditions. Multiple variations of…”
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Nanodiscs as a new tool to examine lipid-protein interactions by Schuler, Mary A, Denisov, Ilia G, Sligar, Stephen G

“…Nanodiscs are self-assembled discoidal fragments of lipid bilayers 8-16 nm in diameter, stabilized in solution by two amphipathic helical scaffold proteins. As…”
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A Small-Gain Approach for Nonpassive Bilateral Telerobotic Rehabilitation: Stability Analysis and Controller Synthesis by Atashzar, Seyed Farokh, Polushin, Ilia G., Patel, Rajnikant V.

“…In this paper, the design of a novel bilateral telerobotic architecture for rehabilitation purposes is proposed and the related feasibility, stability, and…”
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Solvent isotope effects in the catalytic cycle of P450 CYP17A1: Computational modeling of the hydroxylation and lyase reactions by Denisov, Ilia G., Sligar, Stephen G.

“…The catalytic cycle of the cytochromes P450 (CYP) requires two electrons from a protein redox partner and two protons from water to generate the main catalytic…”
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Optical annealing of peroxo-ferric intermediates in CYP17A1 and product formation by Denisov, Ilia G., Grinkova, Yelena V., Sligar, Stephen G.

“…Human cytochrome P450 CYP17A1 catalyzes the hydroxylation of pregnenolone and progesterone at the C17 position, with subsequent C17-C20 bond scission, to form…”
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Cryoradiolysis of oxygenated cytochrome P450 17A1 with lyase substrates generates expected products by Usai, Remigio, Denisov, Ilia G., Sligar, Stephen G., Kincaid, James R.

“…When subjected to γ-irradiation at cryogenic temperatures the oxygenated complexes of Cytochrome P450 CYP17A1 (CYP17A1) bound with either of the lyase…”
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Spectroscopic features of cytochrome P450 reaction intermediates by Luthra, Abhinav, Denisov, Ilia G., Sligar, Stephen G.

“…► Cytochromes P450 provide a rich landscape of spectroscopic features. ► Advantages of various spectroscopic methods for P450 studies are compared. ► Signature…”
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A Generalization of the Scattering Transformation for Conic Systems by Polushin, Ilia G.

“…A generalized version of the scattering transformation is introduced which allows for rendering of the input-output characteristics of a nonlinear conic system…”
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Attitude Synchronization of Multiple Rigid Bodies With Communication Delays by Abdessameud, A., Tayebi, A., Polushin, I. G.

“…We consider the attitude synchronization problem of multiple rigid bodies (or spacecraft) in the presence of communication delays. Specifically, we propose a…”
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SINEs as Potential Expression Cassettes: Impact of Deletions and Insertions on Polyadenylation and Lifetime of B2 and Ves SINE Transcripts Generated by RNA Polymerase III by Borodulina, Olga R., Ustyantsev, Ilia G., Kramerov, Dmitri A.

“…Short Interspersed Elements (SINEs) are common in the genomes of most multicellular organisms. They are transcribed by RNA polymerase III from an internal…”
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Cytochrome b5 enhances androgen synthesis by rapidly reducing the CYP17A1 oxy‐complex in the lyase step by Duggal, Ruchia, Denisov, Ilia G., Sligar, Stephen G.

“…Cytochrome P450 17A1 (CYP17A1) catalyzes the synthesis of androgens from the steroid precursors pregnenolone and progesterone in a two‐step reaction process:…”
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Substrate-Specific Allosteric Effects on the Enhancement of CYP17A1 Lyase Efficiency by Cytochrome b5 by Liu, Yilin, Denisov, Ilia G, Sligar, Stephen G, Kincaid, James R

“…CYP17A1 is an essential human steroidogenic enzyme, which catalyzes two sequential reactions leading to the formation of androstenedione from progesterone and…”
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Unveiling the crucial intermediates in androgen production by Mak, Piotr J., Gregory, Michael C., Denisov, Ilia G., Sligar, Stephen G., Kincaid, James R.

“…Ablation of androgen production through surgery is one strategy against prostate cancer, with the current focus placed on pharmaceutical intervention to…”
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Midazolam as a Probe for Drug–Drug Interactions Mediated by CYP3A4: Homotropic Allosteric Mechanism of Site-Specific Hydroxylation by Denisov, Ilia G, Grinkova, Yelena V, Camp, Tyler, McLean, Mark A, Sligar, Stephen G

“…We developed an efficient and sensitive probe for drug–drug interactions mediated by human CYP3A4 by using midazolam (MDZ) as a probe substrate. Using global…”
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Nanodiscs as a New Tool to Examine Lipid-Protein Interactions by Denisov, Ilia G, Schuler, Mary A, Sligar, Stephen G

“…The interactions between lipids and proteins are one of the most fundamental processes in living organisms, responsible for critical cellular events ranging…”
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