Search Results - "Ilett, E"
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The gut microbiome in patients with chronic lymphocytic leukemia
Published in Haematologica (Roma) (01-09-2022)Get full text
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Metabolic Potential of the Gut Microbiome Is Significantly Impacted by Conditioning Regimen in Allogeneic Hematopoietic Stem Cell Transplantation Recipients
Published in International journal of molecular sciences (01-10-2022)“…Allogeneic hematopoietic stem cell transplantation (aHSCT) is a putative curative treatment for malignant hematologic disorders. During transplantation, the…”
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Lymphokine‐activated killer and dendritic cell carriage enhances oncolytic reovirus therapy for ovarian cancer by overcoming antibody neutralization in ascites
Published in International journal of cancer (01-03-2014)“…Reovirus is an oncolytic virus (OV), which acts by both direct tumor cell killing and priming of antitumor immunity. A major obstacle for effective oncolytic…”
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Prime-boost using separate oncolytic viruses in combination with checkpoint blockade improves anti-tumour therapy
Published in Gene therapy (01-01-2017)“…The anti-tumour effects associated with oncolytic virus therapy are mediated significantly through immune-mediated mechanisms, which depend both on the type of…”
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Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity
Published in Gene therapy (01-05-2009)“…Reovirus is a naturally occurring oncolytic virus currently in early clinical trials. However, the rapid induction of neutralizing antibodies represents a…”
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P603: GUT MICROBIOME IN CHRONIC LYMPHOCYTIC LEUKEMIA SHOWS DEPLETION OF SHORT‐CHAIN FATTY ACIDS PRODUCING BACTERIA
Published in HemaSphere (23-06-2022)Get full text
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Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia
Published in Leukemia (01-09-2015)“…The naturally occurring oncolytic virus (OV), reovirus, replicates in cancer cells causing direct cytotoxicity, and can activate innate and adaptive immune…”
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Cell migration in paediatric glioma; characterisation and potential therapeutic targeting
Published in British journal of cancer (17-02-2015)“…Background: Paediatric high grade glioma (pHGG) and diffuse intrinsic pontine glioma (DIPG) are highly aggressive brain tumours. Their invasive phenotype…”
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Metabolic Profiling Early Post-Allogeneic Haematopoietic Cell Transplantation in the Context of CMV Infection
Published in Metabolites (22-08-2023)“…Immune dysfunction resulting from allogeneic haematopoietic stem cell transplantation (aHSCT) predisposes one to an elevated risk of cytomegalovirus (CMV)…”
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The evolving role of dendritic cells in cancer therapy
Published in Expert opinion on biological therapy (01-03-2010)“…Dendritic cells (DC) are a clear choice for use in cancer immunotherapy, and much research has focused on generating DC for clinical use. Although DC therapy…”
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The Immune System — is it Relevant to Cancer Development, Progression and Treatment?
Published in Clinical oncology (Royal College of Radiologists (Great Britain)) (01-03-2008)“…Abstract The ability of the immune system to effectively respond to human tumours is a matter of long-term controversy. There is an increasing body of recent…”
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Gut microbiome comparability of fresh-frozen versus stabilized-frozen samples from hospitalized patients using 16S rRNA gene and shotgun metagenomic sequencing
Published in Scientific reports (16-09-2019)“…Collection of faecal samples for microbiome analysis in acutely sick patients is logistically difficult, particularly if immediate freezing is required (i.e…”
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Associations of the gut microbiome and clinical factors with acute GVHD in allogeneic HSCT recipients
Published in Blood advances (24-11-2020)“…Acute graft-versus-host disease (aGVHD) is a leading cause of transplantation-related mortality after allogeneic hematopoietic stem cell transplantation…”
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The Importance of the Immune System in Reovirus Therapy
Published in Clinical oncology (Royal College of Radiologists (Great Britain)) (01-12-2008)Get full text
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Incidence Rates and Risk Factors of Clostridioides difficile Infection in Solid Organ and Hematopoietic Stem Cell Transplant Recipients
Published in Open forum infectious diseases (01-04-2019)“…Abstract Background Transplant recipients are an immunologically vulnerable patient group and are at elevated risk of Clostridioides difficile infection (CDI)…”
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Thaumasite investigations to M4 overbridges
Published in Cement & concrete composites (01-12-2003)“…In March 1998, thaumasite sulfate attack (TSA) was discovered affecting several buried raking supports of the Golden Valley Interchange at Junction 11 of the…”
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HIGH GRADE GLIOMAS AND DIPG
Published in Neuro-oncology (Charlottesville, Va.) (01-06-2014)Get full text
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PEDIATRICS LABORATORY RESEARCH
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2013)Get full text
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A pharmacokinetic and pharmacodynamic study of artesunate for vivax malaria
Published in The American journal of tropical medicine and hygiene (01-11-1998)“…To investigate the pharmacokinetic and pharmacodynamic properties of artesunate (ARTS) and its active metabolite dihydroartemisinin (DHA) in Plasmodium vivax…”
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2569. The Gut Microbiome and Acute Graft vs. Host Disease Risk in Hematopoietic Stem Cell Transplantation Recipients
Published in Open forum infectious diseases (23-10-2019)“…Abstract Background 16S rRNA gene-based studies report that allogeneic hematopoietic stem cell transplant (aHSCT) recipients with low bacterial diversity and…”
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