Search Results - "Ildefonso, M"

On the dynamics of the adenylate energy system: homeorhesis vs homeostasis by De la Fuente, Ildefonso M, Cortés, Jesús M, Valero, Edelmira, Desroches, Mathieu, Rodrigues, Serafim, Malaina, Iker, Martínez, Luis

“…Biochemical energy is the fundamental element that maintains both the adequate turnover of the biomolecular structures and the functional metabolic viability…”
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Correspondence insights into the role of genes in cell functionality. Comments on “The gene: An appraisal” by K. Baverstock by De la Fuente, Ildefonso M.

“…One of the most important goals of the post-genomic era is to understand the different sources of molecular information that regulate the functional and…”
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Evidence of conditioned behavior in amoebae by De la Fuente, Ildefonso M., Bringas, Carlos, Malaina, Iker, Fedetz, María, Carrasco-Pujante, Jose, Morales, Miguel, Knafo, Shira, Martínez, Luis, Pérez-Samartín, Alberto, López, José I., Pérez-Yarza, Gorka, Boyano, María Dolores

“…Associative memory is the main type of learning by which complex organisms endowed with evolved nervous systems respond efficiently to certain environmental…”
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Cell Motility and Cancer by De la Fuente, Ildefonso M, López, José I

“…Cell migration is an essential systemic behavior, tightly regulated, of all living cells endowed with directional motility that is involved in the major…”
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First computational design using lambda-superstrings and in vivo validation of SARS-CoV-2 vaccine by Martínez, Luis, Malaina, Iker, Salcines-Cuevas, David, Terán-Navarro, Héctor, Zeoli, Andrea, Alonso, Santos, M. De la Fuente, Ildefonso, Gonzalez-Lopez, Elena, Ocejo-Vinyals, J. Gonzalo, Gozalo-Margüello, Mónica, Calvo-Montes, Jorge, Alvarez-Dominguez, Carmen

“…Coronavirus disease 2019 (COVID-19) is the greatest threat to global health at the present time, and considerable public and private effort is being devoted to…”
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Using Microfluidics for Fast, Accurate Measurement of Lysozyme Nucleation Kinetics by Ildefonso, M, Candoni, N, Veesler, S

“…Here we measure lysozyme nucleation kinetics using an easy-to-use and simply constructed microfluidics setup previously described. We confirm that…”
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Associative Conditioning Is a Robust Systemic Behavior in Unicellular Organisms: An Interspecies Comparison by Carrasco-Pujante, Jose, Bringas, Carlos, Malaina, Iker, Fedetz, Maria, Martínez, Luis, Pérez-Yarza, Gorka, Dolores Boyano, María, Berdieva, Mariia, Goodkov, Andrew, López, José I., Knafo, Shira, De la Fuente, Ildefonso M.

“…The capacity to learn new efficient systemic behavior is a fundamental issue of contemporary biology. We have recently observed, in a preliminary analysis, the…”
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An Approach to Cell Motility as a Key Mechanism in Oncology by López, José I., De la Fuente, Ildefonso M.

“…Motility is an inherent characteristic of living cells manifesting cell migration, a fundamental mechanism of survival and development [...]…”
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Self-Organization and Information Processing: From Basic Enzymatic Activities to Complex Adaptive Cellular Behavior by De la Fuente, Ildefonso M., Martínez, Luis, Carrasco-Pujante, Jose, Fedetz, Maria, López, José I., Malaina, Iker

“…One of the main aims of current biology is to understand the origin of the molecular organization that underlies the complex dynamic architecture of cellular…”
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The nucleus does not significantly affect the migratory trajectories of amoeba in two-dimensional environments by De la Fuente, Ildefonso M., Bringas, Carlos, Malaina, Iker, Regner, Benjamin, Pérez-Samartín, Alberto, Boyano, María Dolores, Fedetz, María, López, José I., Pérez-Yarza, Gorka, Cortes, Jesus M., Sejnowski, Terrence

“…For a wide range of cells, from bacteria to mammals, locomotion movements are a crucial systemic behavior for cellular life. Despite its importance in a…”
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Weighted lambda superstrings applied to vaccine design by Martínez, Luis, Milanič, Martin, Malaina, Iker, Álvarez, Carmen, Pérez, Martín-Blas, M de la Fuente, Ildefonso

“…We generalize the notion of λ-superstrings, presented in a previous paper, to the notion of weighted λ-superstrings. This generalization entails an important…”
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A Universal Antigen-Ranking Method to Design Personalized Vaccines Targeting Neoantigens against Melanoma by Malaina, Iker, Martínez, Luis, Montoya, Juan Manuel, Alonso, Santos, Boyano, María Dolores, Asumendi, Aintzane, Izu, Rosa, Sanchez-Diez, Ana, Cancho-Galan, Goikoane, M de la Fuente, Ildefonso

“…: The main purpose of this article is to introduce a universal mathematics-aided vaccine design method against malignant melanoma based on neoantigens. The…”
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Attractor metabolic networks by De la Fuente, Ildefonso M, Cortes, Jesus M, Pelta, David A, Veguillas, Juan

“…The experimental observations and numerical studies with dissipative metabolic networks have shown that cellular enzymatic activity self-organizes…”
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Nucleation and polymorphism explored via an easy-to-use microfluidic tool by Ildefonso, M., Revalor, Eve, Punniam, P., Salmon, J.B., Candoni, N., Veesler, Stéphane

“…We present an easy-to-use microfluidic set-up, easily transferable to the laboratory and determine an accurate method for metastable zone width measurement. We…”
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Modeling the ascorbate-glutathione cycle in chloroplasts under light/dark conditions by Valero, Edelmira, Macià, Hermenegilda, De la Fuente, Ildefonso M, Hernández, José-Antonio, González-Sánchez, María-Isabel, García-Carmona, Francisco

“…Light/dark cycles are probably the most important environmental signals that regulate plant development. Light is essential for photosynthesis, but an excess,…”
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Vitronectin and dermcidin serum levels predict the metastatic progression of AJCC I–II early‐stage melanoma by Ortega‐Martínez, Idoia, Gardeazabal, Jesús, Erramuzpe, Asier, Sanchez‐Diez, Ana, Cortés, Jesús, García‐Vázquez, María D., Pérez‐Yarza, Gorka, Izu, Rosa, Luís Díaz‐Ramón, Jose, de la Fuente, Ildefonso M., Asumendi, Aintzane, Boyano, María D.

“…Like many cancers, an early diagnosis of melanoma is fundamental to ensure a good prognosis, although an important proportion of stage I–II patients may still…”
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Quantitative analysis of the effective functional structure in yeast glycolysis by De la Fuente, Ildefonso M, Cortes, Jesus M

“…The understanding of the effective functionality that governs the enzymatic self-organized processes in cellular conditions is a crucial topic in the…”
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Systemic cellular migration: The forces driving the directed locomotion movement of cells by De la Fuente, Ildefonso M, Carrasco-Pujante, Jose, Camino-Pontes, Borja, Fedetz, Maria, Bringas, Carlos, Pérez-Samartín, Alberto, Pérez-Yarza, Gorka, López, José I, Malaina, Iker, Cortes, Jesus M

“…Directional motility is an essential property of cells. Despite its enormous relevance in many fundamental physiological and pathological processes, how cells…”
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Elements of the cellular metabolic structure by De la Fuente, Ildefonso M

“…A large number of studies have demonstrated the existence of metabolic covalent modifications in different molecular structures, which are able to store…”
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The metabolic core and catalytic switches are fundamental elements in the self-regulation of the systemic metabolic structure of cells by Fuente, Ildefonso M De la, Cortes, Jesus M, Perez-Pinilla, Martin B, Ruiz-Rodriguez, Vicente, Veguillas, Juan

“…Experimental observations and numerical studies with dissipative metabolic networks have shown that cellular enzymatic activity self-organizes spontaneously…”
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