Search Results - "Ilagan, Roger M"

Mesenchymal stromal cell-derived exosomes improve mitochondrial health in pulmonary arterial hypertension by Hogan, Sarah E, Rodriguez Salazar, Maria Pia, Cheadle, John, Glenn, Rachel, Medrano, Carolina, Petersen, Thomas H, Ilagan, Roger M

“…Secreted exosomes are bioactive particles that elicit profound responses in target cells. Using targeted metabolomics and global microarray analysis, we…”
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Linear measurement of cell contraction in a capillary collagen gel system by Ilagan, Roger, Guthrie, Kelly, Quinlan, Sarah, Rapoport, H Scott, Jones, Sarah, Church, Ashley, Basu, Joydeep, Ludlow, John

“…Three-dimensional collagen gel contraction is the standard assay utilized for functionally quantifying a variety of cell types, in particular smooth muscle…”
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Increased urothelial cell detection in the primary bladder smooth muscle cell cultures with dual MACS/qRT-PCR approach by Genheimer, Chistopher W, Guthrie, Kelly I, Shokes, Jacob E, Bruce, Andrew T, Quinlan, Sarah F, Sangha, Namrata, Ilagan, Roger M, Basu, Joydeep, Burnette, Teresa, Ludlow, John W

“…Bladder tissue has been regenerated in humans with neurogenic bladder using an implant produced from autologous urothelial (UC) and smooth muscle cells (SMC)…”
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Organ specific regenerative markers in peri-organ adipose: kidney by Basu, Joydeep, Genheimer, Christopher W, Sangha, Namrata, Quinlan, Sarah F, Guthrie, Kelly I, Kelley, Rusty, Ilagan, Roger M, Jain, Deepak, Bertram, Timothy, Ludlow, John W

“…Therapeutically bioactive cell populations are currently understood to promote regenerative outcomes in vivo by leveraging mechanisms of action including…”
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Tubular cell-enriched subpopulation of primary renal cells improves survival and augments kidney function in rodent model of chronic kidney disease by Kelley, Rusty, Werdin, Eric S, Bruce, Andrew T, Choudhury, Sumana, Wallace, Shay M, Ilagan, Roger M, Cox, Bryan R, Tatsumi-Ficht, Patricia, Rivera, Elias A, Spencer, Thomas, Rapoport, H Scott, Wagner, Belinda J, Guthrie, Kelly, Jayo, Manuel J, Bertram, Timothy A, Presnell, Sharon C

“…Established chronic kidney disease (CKD) may be identified by severely impaired renal filtration that ultimately leads to the need for dialysis or kidney…”
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Selected renal cells modulate disease progression in rodent models of chronic kidney disease via NF-κB and TGF-β1 pathways by Bruce, Andrew T, Ilagan, Roger M, Guthrie, Kelly I, Rivera, Elias, Choudhury, Sumana, Sangha, Namrata, Spencer, Thomas, Bertram, Timothy A, Jain, Deepak, Kelley, Russell W, Basu, Joydeep

“…Identification of mechanistic pathways for selected renal cell (SRC) therapeutic bioactivity in rodent models of chronic kidney disease. and functional…”
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Regeneration of native-like neo-urinary tissue from nonbladder cell sources by Basu, Joydeep, Jayo, Manuel J, Ilagan, Roger M, Guthrie, Kelly I, Sangha, Namrata, Genheimer, Christopher W, Quinlan, Sarah F, Payne, Richard, Knight, Toyin, Rivera, Elias, Jain, Deepak, Bertram, Timothy A, Ludlow, John W

“…Urinary pathology requiring urinary diversion, partial or full bladder replacement, is a significant clinical problem affecting ~14,000 individuals annually in…”
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Smooth muscle phenotypic diversity is mediated through alterations in Myocardin gene splicing by Ilagan, Roger M., Genheimer, Christopher W., Quinlan, Sarah F., Guthrie, Kelly I., Sangha, Namrata, Ramachandrannair, Sajini, Kelley, Rusty W., Presnell, Sharon C., Basu, Joydeep, Ludlow, John W.

“…Myocardin (MYOCD) is a smooth and cardiac muscle‐specific transcriptional coactivator that is required for the proper expression of contraction‐related genes…”
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Expansion of the human adipose-derived stromal vascular cell fraction yields a population of smooth muscle-like cells with markedly distinct phenotypic and functional properties relative to mesenchymal stem cells by Basu, Joydeep, Genheimer, Christopher W, Guthrie, Kelly I, Sangha, Namrata, Quinlan, Sarah F, Bruce, Andrew T, Reavis, Bethany, Halberstadt, Craig, Ilagan, Roger M, Ludlow, John W

“…Adipose tissue contains a heterogeneous cell population composed of endothelial cells, adipocytes, smooth muscle cells (SMC), and mesenchymal progenitors and…”
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Molecular characterization of the regenerative response induced by intrarenal transplantation of selected renal cells in a rodent model of chronic kidney disease by Genheimer, Christopher W, Ilagan, Roger M, Spencer, Thomas, Kelley, Rusty W, Werdin, Eric, Choudhury, Sumana, Jain, Deepak, Ludlow, John W, Basu, Joydeep

“…Dedifferentiation and proliferation of resident tubular epithelial cells is a mechanism of action potentially contributing to repair and regeneration in…”
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Isolation, characterization, and expansion methods for defined primary renal cell populations from rodent, canine, and human normal and diseased kidneys by Presnell, Sharon C, Bruce, Andrew T, Wallace, Shay M, Choudhury, Sumana, Genheimer, Christopher W, Cox, Bryan, Guthrie, Kelly, Werdin, Eric S, Tatsumi-Ficht, Patricia, Ilagan, Roger M, Kelley, Russell W, Rivera, Elias A, Ludlow, John W, Wagner, Belinda J, Jayo, Manuel J, Bertram, Timothy A

“…Chronic kidney disease (CKD) is a global health problem; the growing gap between the number of patients awaiting transplant and organs actually transplanted…”
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