Search Results - "Ikuta, Kenjiro"

A simple method for producing multiple copies of controlled release small molecule microarrays for cell-based screening by Fujita, Satoshi, Onuki-Nagasaki, Reiko, Ikuta, Kenjiro, Hara, Yusuke

“…Traditional drug discovery involves the screening of lead compounds from a chemical library by using cell-based high throughput screening (HTS) procedures…”
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Mechanism of Mitf inhibition and morphological differentiation effects of hirsein A on B16 melanoma cells revealed by DNA microarray by Villareal, Myra O, Han, Junkyu, Ikuta, Kenjiro, Isoda, Hiroko

“…Abstract Background We have previously reported that hirsein A inhibits melanogenesis in B16 melanoma cells by downregulating the Mitf gene expression…”
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First Functionalized MRI Contrast Agent Recognizing Vascular Lesions by YAMAMOTO, Tatsuhiro, IKUTA, Kenjiro, OI, Keiji, ABE, Kohtaro, UWATOKU, Toyokazu, MURATA, Masaharu, SHIGETANI, Noboru, YOSHIMITSU, Kengo, SHIMOKAWA, Hiroaki, KATAYAMA, Yoshiki

“…A new MRI-contrast agent, EB-DTPA-Gd, that has an Evans Blue analogue as a sensing unit for endothelium lesions, was designed and synthesized. The agent also…”
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Development of polymeric drug delivery system for recognizing vascular endothelial dysfunction by Ikuta, Kenjiro, Mori, Takeshi, Yamamoto, Tatsurhiro, Niidome, Takuro, Shimokawa, Hiroaki, Katayama, Yoshiki

“…The vascular endothelium plays an important role in regulating vascular homeostasis. Damage to the endothelium can lead to cardiovascular diseases such as…”
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Daphnane diterpene hirsein B downregulates melanogenesis in B16 murine melanoma cells by cAMP pathway inhibition by Villareal, Myra O, Han, Junkyu, Ikuta, Kenjiro, Isoda, Hiroko

“…Materials and methods Total RNA was isolated from B16 murine melanoma cells (Riken Cell Bank, Tsukuba, Japan) and used for DNA microarray analysis, using chips…”
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In vivo magnetic resonance imaging of atherosclerotic lesions with a newly developed Evans blue-DTPA-gadolinium contrast medium in apolipoprotein-E-deficient mice by Yasuda, Satoshi, Ikuta, Kenjiro, Uwatoku, Toyokazu, Oi, Keiji, Abe, Kohtaro, Hyodo, Fuminori, Yoshimitsu, Kengo, Sugimura, Kohtaro, Utsumi, Hideo, Katayama, Yoshiki, Shimokawa, Hiroaki

“…Magnetic resonance imaging (MRI) contrast agents that specifically detect atherosclerotic plaque may be useful for the noninvasive detection of the plaque. We…”
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In vivo MR detection of vascular endothelial injury using a new class of MRI contrast agent by Yamamoto, Tatsuhiro, Ikuta, Kenjiro, Oi, Keiji, Abe, Kohtaro, Uwatoku, Toyokazu, Hyodo, Fuminori, Murata, Masaharu, Shigetani, Noboru, Yoshimitsu, Kengo, Shimokawa, Hiroaki, Utsumi, Hideo, Katayama, Yoshiki

“…Graphic A new class of dye-based MRI contrast agents, EB-DTPA-Gd, was designed and synthesized. The contrast agent was found to accumulate at the site of…”
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