Search Results - "Ikura, Hidehiko"

Artificial intelligence-enabled fully automated detection of cardiac amyloidosis using electrocardiograms and echocardiograms by Goto, Shinichi, Mahara, Keitaro, Beussink-Nelson, Lauren, Ikura, Hidehiko, Katsumata, Yoshinori, Endo, Jin, Gaggin, Hanna K., Shah, Sanjiv J., Itabashi, Yuji, MacRae, Calum A., Deo, Rahul C.

“…Patients with rare conditions such as cardiac amyloidosis (CA) are difficult to identify, given the similarity of disease manifestations to more prevalent…”
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Therapeutic Targets for DOX-Induced Cardiomyopathy: Role of Apoptosis vs. Ferroptosis by Kitakata, Hiroki, Endo, Jin, Ikura, Hidehiko, Moriyama, Hidenori, Shirakawa, Kohsuke, Katsumata, Yoshinori, Sano, Motoaki

“…Doxorubicin (DOX) is the most widely used anthracycline anticancer agent; however, its cardiotoxicity limits its clinical efficacy. Numerous studies have…”
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A Reliable Baton Passing From Orthopedic Surgeon to Cardiologist　― Cardiac Screening in Patients With Carpal Tunnel Syndrome for Early Diagnosis of Transthyretin Amyloid Cardiomyopathy by Ikura, Hidehiko, Kitakata, Hiroki, Endo, Jin

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A novel device for detecting anaerobic threshold using sweat lactate during exercise by Seki, Yuta, Nakashima, Daisuke, Shiraishi, Yasuyuki, Ryuzaki, Toshinobu, Ikura, Hidehiko, Miura, Kotaro, Suzuki, Masato, Watanabe, Takatomo, Nagura, Takeo, Matsumato, Morio, Nakamura, Masaya, Sato, Kazuki, Fukuda, Keiichi, Katsumata, Yoshinori

“…The lactate threshold (LT1), which is defined as the first rise in lactate concentration during incremental exercise, has not been non-invasively and…”
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MITOL/MARCH5 determines the susceptibility of cardiomyocytes to doxorubicin-induced ferroptosis by regulating GSH homeostasis by Kitakata, Hiroki, Endo, Jin, Matsushima, Hirokazu, Yamamoto, Shoichi, Ikura, Hidehiko, Hirai, Akeo, Koh, Seien, Ichihara, Genki, Hiraide, Takahiro, Moriyama, Hidenori, Shirakawa, Kohsuke, Goto, Shinichi, Katsumata, Yoshinori, Anzai, Atsushi, Kataoka, Masaharu, Tokuyama, Takeshi, Ishido, Satoshi, Yanagi, Shigeru, Fukuda, Keiichi, Sano, Motoaki

“…MITOL/MARCH5 is an E3 ubiquitin ligase that plays a crucial role in the control of mitochondrial quality and function. However, the significance of MITOL in…”
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Molecular Mechanism of Pathogenesis and Treatment Strategies for AL Amyloidosis by Ikura, Hidehiko, Endo, Jin, Kitakata, Hiroki, Moriyama, Hidenori, Sano, Motoaki, Fukuda, Keiichi

“…In amyloid light-chain (AL) amyloidosis, small B-cell clones (mostly plasma cell clones) present in the bone marrow proliferate and secrete unstable monoclonal…”
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Exercise tolerance and quality of life in hemodynamically partially improved patients with chronic thromboembolic pulmonary hypertension treated with balloon pulmonary angioplasty by Miura, Kotaro, Katsumata, Yoshinori, Kawakami, Takashi, Ikura, Hidehiko, Ryuzaki, Toshinobu, Shiraishi, Yasuyuki, Fukui, Shogo, Kawakami, Michiyuki, Kohno, Takashi, Sato, Kazuki, Fukuda, Keiichi

“…The efficacy of extensive balloon pulmonary angioplasty (BPA) beyond hemodynamic improvement in chronic thromboembolic pulmonary hypertension (CTEPH) patients…”
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Sweat lactate sensor for detecting anaerobic threshold in heart failure: a prospective clinical trial (LacS-001) by Katsumata, Yoshinori, Muramoto, Yuki, Ishida, Noriyuki, Takemura, Ryo, Nagashima, Kengo, Ikoma, Takenori, Kawamatsu, Naoto, Araki, Masaru, Goda, Ayumi, Okawara, Hiroki, Sawada, Tomonori, Ichihara, Yumiko Kawakubo, Hattori, Osamu, Yamaoka, Koki, Seki, Yuta, Ryuzaki, Toshinobu, Ikura, Hidehiko, Nakashima, Daisuke, Nagura, Takeo, Nakamura, Masaya, Sato, Kazuki, Shiraishi, Yasuyuki

“…A simple method for determining the anaerobic threshold in patients with heart failure (HF) is needed. This prospective clinical trial (LacS-001) aimed to…”
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Feasibility of the deep learning method for estimating the ventilatory threshold with electrocardiography data by Miura, Kotaro, Goto, Shinichi, Katsumata, Yoshinori, Ikura, Hidehiko, Shiraishi, Yasuyuki, Sato, Kazuki, Fukuda, Keiichi

“…Regular aerobic physical activity is of utmost importance in maintaining a good health status and preventing cardiovascular diseases (CVDs). Although…”
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Treatment of transthyretin His88Arg amyloidosis with RNA interference therapy: A case report by Kitakata, Hiroki, Moriyama, Hidenori, Endo, Jin, Ikura, Hidehiko, Fukuda, Keiichi, Sano, Motoaki

“…A new class of medicines called small interfering RNA molecule has demonstrated beneficial effects in patients with amyloidosis associated with mutations in…”
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Real-time analysis of heart rate variability during aerobic exercise in patients with cardiovascular disease by Ikura, Hidehiko, Katsumata, Yoshinori, Seki, Yuta, Ryuzaki, Toshinobu, Shiraishi, Yasuyuki, Miura, Kotaro, Sato, Kazuki, Fukuda, Keiichi

“…Exercise therapy for cardiovascular disease (CVD) is mainly evaluated based on the heart rate (HR) or Borg scale. However, these indices can be unreliable…”
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Qualitative and Quantitative Effects of Fatty Acids Involved in Heart Diseases by Moriyama, Hidenori, Endo, Jin, Ikura, Hidehiko, Kitakata, Hiroki, Momoi, Mizuki, Shinya, Yoshiki, Ko, Seien, Ichihara, Genki, Hiraide, Takahiro, Shirakawa, Kohsuke, Anzai, Atsushi, Katsumata, Yoshinori, Sano, Motoaki

“…Fatty acids (FAs) have structural and functional diversity. FAs in the heart are closely associated with cardiac function, and their qualitative or…”
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Step‐by‐step typing for the accurate diagnosis of concurrent light chain and transthyretin cardiac amyloidosis by Moriyama, Hidenori, Kitakata, Hiroki, Endo, Jin, Ikura, Hidehiko, Sano, Motoaki, Tasaki, Masayoshi, Sakai, Shunta, Ueda, Mitsuharu, Fukuda, Keiichi

“…While 99mTc‐pyrophosphate scintigraphy is clearly useful in diagnosing transthyretin amyloid cardiomyopathy (ATTR‐CM), it is necessary to know the pitfalls of…”
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Abstract 15130: Sweat Lactate Sensor for Detecting Anaerobic Threshold in Paitents With Heart Failure: Prospective Clinical Trial (LacS-001) by Kawakubo Ichihara, Yumiko, Yamaoka, Kouki, Ryuzaki, Toshinobu, Ikura, Hidehiko, Nakashima, Daisuke, Shiraishi, Yasuyuki, Ieda, Masaki, Yoshinori, Katsumata

“…Abstract only Background: Exercise is essential for good health and prevention of exacerbations in patients with heart failure (HF). To determine ventilatory…”
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Abstract 11222: A Combined, Fully Automated Electrocardiogram and Echocardiogram Strategy for Detection of Hypertrophic Cardiomyopathy by Goto, Shinichi, Ichihara, Genki, Ikura, Hidehiko, Katsumata, Yoshinori, Itabashi, Yuji, Macrae, Calum, Deo, Rahul C

“…IntroductionHypertrophic cardiomyopathy (HCM) is a disorder characterized by abnormal thickening of the heart muscle and may affect up to 1 in 200 people in…”
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Abstract 13134: A Novel Device for Detecting Anaerobic Threshold Using Sweat Lactate Acid During Exercise by Seki, Yuta, Nakashima, Daisuke, Toshinobu, Ryuzaki, Ikura, Hidehiko, Miura, Kotaro, Shiraishi, Yasuyuki, Fukuda, Keiichi, Katsumata, Yoshinori

“…BackgroundContinuous monitoring of lactate acid (LA) levels during exercise has not been possible. We aimed to visualize real-time changes in LA levels in…”
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Early Diagnosis of Amyloid Cardiomyopathy by Moriyama, Hidenori, Kitakata, Hiroki, Endo, Jin, Ikura, Hidehiko, Fukuda, Keiichi

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Early Diagnosis of Amyloid Cardiomyopathy: Potential and Need Before the Onset of Decompensated Heart Failure by Moriyama, Hidenori, Kitakata, Hiroki, Endo, Jin, Ikura, Hidehiko, Fukuda, Keiichi

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Real-Time Estimation of Anaerobic Threshold during Exercise Using Electrocardiogram in Heart Failure Patients by Ryuzaki, Toshinobu, Shiraishi, Yasuyuki, Miura, Kotaro, Ikura, Hidehiko, Seki, Yuta, Azuma, Koichiro, Sato, Kazuki, Fukuda, Keiichi, Katsumata, Yoshinori

“…Exercise therapy at the aerobic level is highly recommended to improve clinical outcomes in patients with heart failure, in which cardiopulmonary exercise…”
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Three patients of transthyretin amyloidosis in a Japanese family with amyloidogenic transthyretin Thr49Ser (p.Thr69Ser) variant by Ikura, Hidehiko, Kitakata, Hiroki, Endo, Jin, Moriyama, Hidenori, Sano, Motoaki, Tsujikawa, Hanako, Sawano, Mitsuaki, Masuda, Teruaki, Ohki, Takahiro, Ueda, Mitsuharu, Kosaki, Kenjiro, Fukuda, Keiichi

“…Transthyretin (TTR)-related hereditary amyloidosis (ATTRv) is a rare autosomal dominant disorder that is caused by pathogenic missense mutation of the TTR…”
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