Search Results - "Ikemoto, Nori"
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Highly Efficient Asymmetric Synthesis of Sitagliptin
Published in Journal of the American Chemical Society (01-07-2009)“…A highly efficient synthesis of sitagliptin, a potent and selective DPP-4 inhibitor for the treatment of type 2 diabetes mellitus (T2DM), has been developed…”
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Quantitation and characterization of serotype 6A activation for pneumococcal conjugate vaccine by cryo-EM and SEC methods
Published in Vaccine (14-11-2024)“…Pneumococcal conjugate vaccines (PCV) typically consist of capsular polysaccharides from different S. pneumoniae serotypes which are covalently attached to…”
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Correction to “Highly Efficient Asymmetric Synthesis of Sitagliptin”
Published in Journal of the American Chemical Society (05-08-2020)Get full text
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Improving the In Vivo Therapeutic Index of siRNA Polymer Conjugates through Increasing pH Responsiveness
Published in Bioconjugate chemistry (19-02-2014)“…Polymer based carriers that aid in endosomal escape have proven to be efficacious siRNA delivery agents in vitro and in vivo; however, most suffer from…”
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Efficient synthesis of the optically active dihydropyrimidinone of a potent α 1A - selective adrenoceptor antagonist
Published in Canadian journal of chemistry (01-06-2002)“…The convergent synthesis of a potent α 1A -selective adrenoceptor antagonist is described. Salient features of the synthesis include the enzymatic resolution…”
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Efficient synthesis of the optically active dihydropyrimidinone of a potent 1A- selective adrenoceptor antagonist
Published in Canadian journal of chemistry (01-06-2002)“…The convergent synthesis of a potent 1A -selective adrenoceptor antagonist is described. Salient features of the synthesis include the enzymatic resolution of…”
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Journal Article