Search Results - "Ikeh, Mélanie A C"
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An expanded cell wall damage signaling network is comprised of the transcription factors Rlm1 and Sko1 in Candida albicans
Published in PLoS genetics (08-07-2020)“…The human fungal pathogen Candida albicans is constantly exposed to environmental challenges impacting the cell wall. Signaling pathways coordinate stress…”
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Blocking two-component signalling enhances Candida albicans virulence and reveals adaptive mechanisms that counteract sustained SAPK activation
Published in PLoS pathogens (01-01-2017)“…The Ypd1 phosphorelay protein is a central constituent of fungal two-component signal transduction pathways. Inhibition of Ypd1 in Saccharomyces cerevisiae and…”
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Transcriptional regulation of the caspofungin-induced cell wall damage response in Candida albicans
Published in Current genetics (01-12-2020)“…The human fungal pathogen Candida albicans maintains pathogenic and commensal states primarily through cell wall functions. The echinocandin antifungal drug…”
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Prostaglandin E2 Receptor Antagonist with Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus
Published in Antimicrobial agents and chemotherapy (23-02-2018)“…Polymicrobial intra-abdominal infections (IAI) involving Candida albicans and Staphylococcus aureus are associated with severe morbidity and mortality (∼80%)…”
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Blocking Polyphosphate Mobilization Inhibits Pho4 Activation and Virulence in the Pathogen Candida albicans
Published in mBio (28-06-2022)“…The ability of pathogenic fungi to obtain essential nutrients from the host is vital for virulence. In Candida albicans, acquisition of the macronutrient…”
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Prostaglandin E 2 Receptor Antagonist with Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus
Published in Antimicrobial agents and chemotherapy (01-03-2018)“…Polymicrobial intra-abdominal infections (IAI) involving and are associated with severe morbidity and mortality (∼80%). Our laboratory discovered that the…”
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Identification of Specific Components of the Eicosanoid Biosynthetic and Signaling Pathway Involved in pathological inflammation during Intra-abdominal Infection with Candida albicans and Staphylococcus aureus
Published in Infection and immunity (01-07-2018)“…Polymicrobial intra-abdominal infections (IAI) are a significant cause of morbidity and mortality, particularly when fungal pathogens are involved. Our…”
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Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis
Published in Molecular biology of the cell (01-09-2016)“…During interactions with its mammalian host, the pathogenic yeast Candida albicans is exposed to a range of stresses such as superoxide radicals and cationic…”
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In Situ Imaging of Candida albicans Hyphal Growth via Atomic Force Microscopy
Published in mSphere (04-11-2020)“…is an opportunistic fungal pathogen of humans known for its ability to cause a wide range of infections. One major virulence factor of is its ability to form…”
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italic toggle="yes">In Situ /italic> Imaging of Candida albicans Hyphal Growth via Atomic Force Microscopy
Published in mSphere (01-12-2020)“…ABSTRACT Candida albicans is an opportunistic fungal pathogen of humans known for its ability to cause a wide range of infections. One major virulence factor…”
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