Search Results - "Ikeda, Kenji"

Recent advances in medical management of hepatocellular carcinoma by Ikeda, Kenji

“…Transcatheter arterial therapies for hepatocellular carcinoma (HCC) have developed during the last decade. A fine powder formulation of cisplatin and the new…”
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Uninformative anchoring effect in judgments of learning by Ikeda, Kenji

“…This experimental study examined whether the uninformative anchoring effect, which should be ignored, on judgments of learning (JOLs) was eliminated through…”
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The Common and Distinct Features of Brown and Beige Adipocytes by Ikeda, Kenji, Maretich, Pema, Kajimura, Shingo

“…Two types of thermogenic fat cells, brown adipocytes and beige adipocytes, play a key role in the regulation of systemic energy homeostasis in mammals. Both…”
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UCP1 Dependent and Independent Thermogenesis in Brown and Beige Adipocytes by Ikeda, Kenji, Yamada, Tetsuya

“…Mammals have two types of thermogenic adipocytes: brown adipocytes and beige adipocytes. Thermogenic adipocytes express high levels of uncoupling protein 1…”
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Mitophagy controls beige adipocyte maintenance through a Parkin-dependent and UCP1-independent mechanism by Lu, Xiaodan, Altshuler-Keylin, Svetlana, Wang, Qiang, Chen, Yong, Henrique Sponton, Carlos, Ikeda, Kenji, Maretich, Pema, Yoneshiro, Takeshi, Kajimura, Shingo

“…Beige adipocytes are an inducible form of mitochondria-enriched thermogenic adipocytes that emerge in response to external stimuli, such as chronic cold…”
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REFLECT—a phase 3 trial comparing efficacy and safety of lenvatinib to sorafenib for the treatment of unresectable hepatocellular carcinoma: an analysis of Japanese subset by Yamashita, Tatsuya, Kudo, Masatoshi, Ikeda, Kenji, Izumi, Namiki, Tateishi, Ryosuke, Ikeda, Masafumi, Aikata, Hiroshi, Kawaguchi, Yasunori, Wada, Yoshiyuki, Numata, Kazushi, Inaba, Yoshitaka, Kuromatsu, Ryoko, Kobayashi, Masahiro, Okusaka, Takuji, Tamai, Toshiyuki, Kitamura, Chifumi, Saito, Kenichi, Haruna, Katsuya, Okita, Kiwamu, Kumada, Hiromitsu

“…Background A phase 3, multinational, randomized, non-inferiority trial (REFLECT) compared the efficacy and safety of lenvatinib (LEN) and sorafenib (SOR) in…”
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Thermal stress induces glycolytic beige fat formation via a myogenic state by Chen, Yong, Ikeda, Kenji, Yoneshiro, Takeshi, Scaramozza, Annarita, Tajima, Kazuki, Wang, Qiang, Kim, Kyeongkyu, Shinoda, Kosaku, Sponton, Carlos Henrique, Brown, Zachary, Brack, Andrew, Kajimura, Shingo

“…Environmental cues profoundly affect cellular plasticity in multicellular organisms. For instance, exercise promotes a glycolytic-to-oxidative fibre-type…”
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Phase 2 study of lenvatinib in patients with advanced hepatocellular carcinoma by Ikeda, Kenji, Kudo, Masatoshi, Kawazoe, Seiji, Osaki, Yukio, Ikeda, Masafumi, Okusaka, Takuji, Tamai, Toshiyuki, Suzuki, Takuya, Hisai, Takashi, Hayato, Seiichi, Okita, Kiwamu, Kumada, Hiromitsu

“…Background Lenvatinib is an oral inhibitor of vascular endothelial growth factor receptor 1–3, fibroblast growth factor receptor 1–4, platelet-derived growth…”
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Wireless optogenetics protects against obesity via stimulation of non-canonical fat thermogenesis by Tajima, Kazuki, Ikeda, Kenji, Tanabe, Yuji, Thomson, Ella A., Yoneshiro, Takeshi, Oguri, Yasuo, Ferro, Marc D., Poon, Ada S. Y., Kajimura, Shingo

“…Cold stimuli and the subsequent activation of β-adrenergic receptor (β-AR) potently stimulate adipose tissue thermogenesis and increase whole-body energy…”
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A neural network-based local rainfall prediction system using meteorological data on the Internet: A case study using data from the Japan Meteorological Agency by Kashiwao, Tomoaki, Nakayama, Koichi, Ando, Shin, Ikeda, Kenji, Lee, Moonyong, Bahadori, Alireza

“…[Display omitted] •Local rainfall prediction system based on neural networks (NNs) using meteorological data obtained from the Internet is developed, and local…”
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Adipose tissue thermogenesis by calcium futile cycling by Ikeda, Kenji, Yamada, Tetsuya

“…Abstract Brown and beige adipocytes produce heat and control systemic energy via non-shivering thermogenesis. Historically, thermogenesis in brown and beige…”
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Does implicit theory of intelligence moderate judgment of learning-based study time allocation? by Ikeda, Kenji, Jiang, Juming, Kakinuma, Kyosuke, Tanaka, Ayumi

“…Prior research demonstrated that the theory of intelligence (TOI), which included incremental theory (intelligence is a malleable trait and develops…”
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Impact of sodium glucose cotransporter 2 inhibitor on histological features and glucose metabolism of non‐alcoholic fatty liver disease complicated by diabetes mellitus by Akuta, Norio, Kawamura, Yusuke, Watanabe, Chizuru, Nishimura, Akihiro, Okubo, Minoru, Mori, Yasumichi, Fujiyama, Shunichiro, Sezaki, Hitomi, Hosaka, Tetsuya, Kobayashi, Masahiro, Kobayashi, Mariko, Saitoh, Satoshi, Suzuki, Fumitaka, Suzuki, Yoshiyuki, Arase, Yasuji, Ikeda, Kenji, Kumada, Hiromitsu

“…Aim The aim of this study was to investigate the therapeutic potential of sodium glucose cotransporter 2 inhibitor (SGLT2I) as an effective therapeutic option…”
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Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis by Hasegawa, Yutaka, Ikeda, Kenji, Chen, Yong, Alba, Diana L., Stifler, Daniel, Shinoda, Kosaku, Hosono, Takashi, Maretich, Pema, Yang, Yangyu, Ishigaki, Yasushi, Chi, Jingyi, Cohen, Paul, Koliwad, Suneil K., Kajimura, Shingo

“…Adipose tissue fibrosis is a hallmark of malfunction that is linked to insulin resistance and type 2 diabetes; however, what regulates this process remains…”
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Time-to-Interventional Failure as a New Surrogate Measure for Survival Outcomes after Resection of Hepatocellular Carcinoma by Shindoh, Junichi, Kawamura, Yusuke, Kobayashi, Yuta, Akuta, Norio, Kobayashi, Masahiro, Suzuki, Yoshiyuki, Ikeda, Kenji, Hashimoto, Masaji

“…Purpose This study sought to investigate the clinical impact of repeated interventions for recurrent hepatocellular carcinoma (HCC) and to establish a new…”
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Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma by HOSHIDA, Yujin, NIJMAN, Sebastian M. B, WATANABE, Goro, GABRIEL, Stacey, FRIEDMAN, Scott L, KUMADA, Hiromitsu, LLOVET, Josep M, GOLUB, Todd R, KOBAYASHI, Masahiro, CHAN, Jennifer A, BRUNET, Jean-Philippe, CHIANG, Derek Y, VILLANUEVA, Augusto, NEWELL, Philippa, IKEDA, Kenji, HASHIMOTO, Masaji

“…Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, and prior attempts to develop genomic-based classification for HCC have yielded highly…”
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SGLT2 Inhibitor Treatment Outcome in Nonalcoholic Fatty Liver Disease Complicated with Diabetes Mellitus: The Long-term Effects on Clinical Features and Liver Histopathology by Akuta, Norio, Kawamura, Yusuke, Fujiyama, Shunichiro, Sezaki, Hitomi, Hosaka, Tetsuya, Kobayashi, Masahiro, Kobayashi, Mariko, Saitoh, Satoshi, Suzuki, Fumitaka, Suzuki, Yoshiyuki, Arase, Yasuji, Ikeda, Kenji, Kumada, Hiromitsu

“…Objective The aim of this study was to determine the long-term effects of a sodium-glucose cotransporter 2 inhibitor (SGLT2i) in nonalcoholic fatty liver…”
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Direct-Acting Antivirals Decreased Tumor Recurrence After Initial Treatment of Hepatitis C Virus-Related Hepatocellular Carcinoma by Ikeda, Kenji, Kawamura, Yusuke, Kobayashi, Masahiro, Kominami, Yoko, Fujiyama, Shunichiro, Sezaki, Hitomi, Hosaka, Tetsuya, Akuta, Norio, Saitoh, Satoshi, Suzuki, Fumitaka, Suzuki, Yoshiyuki, Arase, Yasuji, Kumada, Hiromitsu

“…Background Suppressive activity of recurrence by interferon-free direct-acting antivirals (DAA) is not elucidated after curative treatment of hepatocellular…”
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The Role of Thermogenic Fat Tissue in Energy Consumption by Horino, Masato, Ikeda, Kenji, Yamada, Tetsuya

“…Mammalian adipose tissues are broadly divided into white adipose tissue (WAT) and thermogenic fat tissue (brown adipose tissue and beige adipose tissue)…”
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Efficacy and safety of glecaprevir/pibrentasvir in HCV-infected Japanese patients with prior DAA experience, severe renal impairment, or genotype 3 infection by Kumada, Hiromitsu, Watanabe, Tsunamasa, Suzuki, Fumitaka, Ikeda, Kenji, Sato, Ken, Toyoda, Hidenori, Atsukawa, Masanori, Ido, Akio, Takaki, Akinobu, Enomoto, Nobuyuki, Kato, Koji, Alves, Katia, Burroughs, Margaret, Redman, Rebecca, Pugatch, David, Pilot-Matias, Tami J., Krishnan, Preethi, Oberoi, Rajneet K., Xie, Wangang, Chayama, Kazuaki

“…Background Once-daily, orally administered, co-formulated glecaprevir (NS3/4A protease inhibitor) and pibrentasvir (NS5A inhibitor) (G/P) demonstrated…”
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