Search Results - "Ikeda, Jiro"
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PPARγ Agonists Attenuate Palmitate-Induced ER Stress through Up-Regulation of SCD-1 in Macrophages
Published in PloS one (10-06-2015)“…Clinical trials have shown that treatment of patients with type 2 diabetes with pioglitazone, a peroxisome proliferator-activated receptor (PPAR)γ agonist,…”
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Right Coronary Artery with an Intramural and Interarterial Course as a Unique Cause of Myocardial Ischemia: The Unroofing Method Might Still Be the Best Solution
Published in Internal Medicine (01-03-2023)“…A 39-year-old man was admitted because of cardiac arrest. Emergent coronary angiography revealed a preserved coronary blood flow; however, multiple-row…”
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Prolyl Hydroxylase Domain Protein 2 Plays a Critical Role in Diet-Induced Obesity and Glucose Intolerance
Published in Circulation (New York, N.Y.) (28-05-2013)“…BACKGROUND—Recent studies suggest that the oxygen-sensing pathway consisting of transcription factor hypoxia-inducible factor and prolyl hydroxylase domain…”
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Excision repair cross‐complementation group 1 predicts progression‐free and overall survival in non‐small cell lung cancer patients treated with platinum‐based chemotherapy
Published in Cancer science (01-09-2007)“…Expression of excision repair cross‐complementation group 1 (ERCC1), p53, or thioredoxin (TRX) is reported to be correlated with resistance to platinum‐based…”
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Suppression of abdominal aortic aneurysm formation by inhibition of prolyl hydroxylase domain protein through attenuation of inflammation and extracellular matrix disruption
Published in Clinical science (1979) (01-05-2014)“…In the present study we sought to determine the effect of CoCl2, an inhibitor of PHD (prolyl hydroxylase domain protein), on the development of AAA (abdominal…”
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Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux
Published in Communications biology (15-02-2022)“…Atherosclerosis is a chronic inflammatory condition in which macrophages play a major role. Janus kinase 2 (JAK2) is a pivotal molecule in inflammatory and…”
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Inhibition of MDM2 attenuates neointimal hyperplasia via suppression of vascular proliferation and inflammation
Published in Cardiovascular research (01-09-2011)“…Tumour protein p53 plays an important role in the vascular remodelling process as well as in oncogenesis. p53 is negatively regulated by murine double minute 2…”
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Stimulation of α7 nicotinic acetylcholine receptor by AR-R17779 suppresses atherosclerosis and aortic aneurysm formation in apolipoprotein E-deficient mice
Published in Vascular pharmacology (01-05-2014)“…Abstract Atherosclerosis is a chronic inflammatory disease. It has been appreciated that vagus nerve inhibits macrophage activation via α7 nicotinic…”
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Suppression of abdominal aortic aneurysm formation by AR-R17779, an agonist for the α7 nicotinic acetylcholine receptor
Published in Atherosclerosis (01-01-2016)“…Abstract Objective Activation of vagal nerve suppresses inflammatory responses through activation of α7 nicotinic acetylcholine receptor (nAchR). We sought to…”
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Inhibition of Prolyl Hydroxylase Domain-Containing Protein Downregulates Vascular Angiotensin II Type 1 Receptor
Published in Hypertension (Dallas, Tex. 1979) (01-09-2011)“…Inhibition of prolyl hydroxylase domain-containing protein (PHD) by hypoxia stabilizes hypoxia-inducible factor 1 and increases the expression of target genes,…”
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Acetylcholinesterase inhibitors attenuate angiogenesis
Published in Clinical science (1979) (01-08-2012)“…Donepezil {(RS)-2-[(1-benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one} is a reversible acetylcholinesterase inhibitor and used for treatment of…”
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Application of Hydrothermal Treatment on BF Slag and Waste Glass for Preparing Lubricant Materials in High Strain Rolling for Ultrafine-grained Steel Production
Published in ISIJ International (01-01-2008)“…In order to establish a high strain rolling process for the production of ultrafine-grained steels, a new lubricant showing stable biting between rolls and…”
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Serum carcinoembryonic antigen as a predictive marker for sensitivity to gefitinib in advanced non-small cell lung cancer
Published in European journal of cancer (1990) (01-06-2005)“…Gefitinib is an inhibitor of epidermal growth factor receptor tyrosine kinase, which has a tumour reducing effect in non-small cell lung cancer (NSCLC). In…”
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Correlation of Decreased Survival and IL-18 in Bone Metastasis
Published in Internal Medicine (01-01-2009)“…Objective Previous studies have reported that serum IL-18 levels are increased in some cancers. We investigated whether IL-18 production is increased in sera…”
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Induction chemoradiotherapy and surgical resection for selected stage IIIB non–small-cell lung cancer
Published in The Annals of thoracic surgery (01-12-2003)“…Combination chemotherapy using an oral combination of uracil and tegafur (UFT) plus cisplatin and concurrent thoracic radiotherapy is reported to have a high…”
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Use of Slag Containing Water as a Lubricant in High Straining Rolling for Ultrafine-grained Steels
Published in ISIJ International (2005)“…We investigated the possibility of using waste slag as a lubricant in high straining rolling for ultrafine-grained steels. When slag is applied as a lubricant,…”
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A Prospective Japanese Study of the Association between Personality and the Progression of Lung Cancer
Published in Internal Medicine (01-01-2006)“…Objective: To examine predictive values for the effect of the "Type 1" (hopeless and emotionsuppressive, cancer prone), "Type 4" (autonomous, healthy), and…”
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Necessity of preoperative screening for brain metastasis in non-small cell lung cancer patients without lymph node metastasis
Published in Annals of thoracic and cardiovascular surgery (01-12-2004)“…The exclusion of brain metastasis is important to determine the optimal treatment plan in patients with non-small cell lung cancer (NSCLC). However, a routine…”
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Phase I Study of Amrubicin Hydrochloride and Cisplatin in Patients Previously Treated for Advanced Non-small Cell Lung Cancer
Published in Japanese journal of clinical oncology (01-01-2006)“…Objective: A single-center phase I trial was designed to determine both the dose-limiting toxicities and the maximum tolerated dose (MTD) for amrubicin…”
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Endothelial HMGB1 Is a Critical Regulator of LDL Transcytosis via an SREBP2–SR-BI Axis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-01-2021)“…OBJECTIVE:LDL (low-density lipoprotein) transcytosis across the endothelium is performed by the SR-BI (scavenger receptor class B type 1) receptor and…”
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