Search Results - "Ikdahl, Tone"

Phase III Trial of Cetuximab With Continuous or Intermittent Fluorouracil, Leucovorin, and Oxaliplatin (Nordic FLOX) Versus FLOX Alone in First-Line Treatment of Metastatic Colorectal Cancer: The NORDIC-VII Study by MAGNE TVEIT, Kjell, GUREN, Tormod, FOKSTUEN, Tone, HANSEN, Flemming, HOFSLI, Eva, BIRKEMEYER, Elke, JOHNSSON, Anders, STARKHAMMAR, Hans, YILMAZ, Mette Karen, KELDSEN, Nina, BERIT ERDAL, Anne, DAJANI, Olav, GLIMELIUS, Bengt, DAHL, Olav, CHRISTOFFERSEN, Thoralf, PFEIFFER, Per, SORBYE, Halfdan, PYRHONEN, Seppo, SIGURDSSON, Fridbjorn, KURE, Elin, IKDAHL, Tone, SKOVLUND, Eva

“…The NORDIC-VII multicenter phase III trial investigated the efficacy of cetuximab when added to bolus fluorouracil/folinic acid and oxaliplatin (Nordic FLOX),…”
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Randomized, Multicenter, Phase II Study of CO-101 Versus Gemcitabine in Patients With Metastatic Pancreatic Ductal Adenocarcinoma: Including a Prospective Evaluation of the Role of hENT1 in Gemcitabine or CO-101 Sensitivity by POPLIN, Elizabeth, WASAN, Harpreet, ORMANNS, Steffen, HEINEMANN, Volker, BASSI, Claudio, EVANS, T. R. Jeffrey, ANDERSSON, Roland, HEJIN HAHN, PICOZZI, Vince, DICKER, Adam, MANN, Elaina, VOONG, Cynthia, ROLFE, Lindsey, KAUR, Paramjit, ISAACSON, Jeff, ALLEN, Andrew, RAPONI, Mitch, IKDAHL, Tone, BONDARENKO, Ihor, DAVIDENKO, Irina, BONDAR, Volodymyr, GARIN, August, BOECK, Stefan

“…Gemcitabine requires transporter proteins to cross cell membranes. Low expression of human equilibrative nucleoside transporter-1 (hENT1) may result in…”
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Differential expression of miRNAs in colorectal cancer: comparison of paired tumor tissue and adjacent normal mucosa using high-throughput sequencing by Hamfjord, Julian, Stangeland, Astrid M, Hughes, Timothy, Skrede, Martina L, Tveit, Kjell M, Ikdahl, Tone, Kure, Elin H

“…We present the results of a global study of dysregulated miRNAs in paired samples of normal mucosa and tumor from eight patients with colorectal cancer…”
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Interleukin-6 and C-reactive protein as prognostic biomarkers in metastatic colorectal cancer by Thomsen, Maria, Kersten, Christian, Sorbye, Halfdan, Skovlund, Eva, Glimelius, Bengt, Pfeiffer, Per, Johansen, Julia S, Kure, Elin H, Ikdahl, Tone, Tveit, Kjell Magne, Christoffersen, Thoralf, Guren, Tormod Kyrre

“…The aim was to explore the prognostic significance of IL-6 and markers of systemic inflammatory response (SIR), in particular C-reactive protein (CRP), in…”
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Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer by Mezheyeuski, Artur, Bradic Lindh, Maja, Guren, Tormod Kyrre, Dragomir, Anca, Pfeiffer, Per, Kure, Elin H, Ikdahl, Tone, Skovlund, Eva, Corvigno, Sara, Strell, Carina, Pietras, Kristian, Ponten, Fredrik, Mulder, Jan, Qvortrup, Camilla, Portyanko, Anna, Tveit, Kjell Magne, Glimelius, Bengt, Sorbye, Halfdan, Östman, Arne

“…Perivascular cells (PC) were recently implied as regulators of metastasis and immune cell activity. Perivascular heterogeneity in clinical samples, and…”
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Let-7 miRNA-binding site polymorphism in the KRAS 3′UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/− cetuximab by Kjersem, Janne B, Ikdahl, Tone, Guren, Tormod, Skovlund, Eva, Sorbye, Halfdan, Hamfjord, Julian, Pfeiffer, Per, Glimelius, Bengt, Kersten, Christian, Solvang, Hiroko, Tveit, Kjell M, Kure, Elin H

“…Abstract Background Recent studies have reported associations between a variant allele in a let-7 microRNA complementary site (LCS6) within the 3 ′…”
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The level of claudin-7 is reduced as an early event in colorectal carcinogenesis by Bornholdt, Jette, Friis, Stine, Godiksen, Sine, Poulsen, Steen S, Santoni-Rugiu, Eric, Bisgaard, Hanne C, Lothe, Inger M B, Ikdahl, Tone, Tveit, Kjell M, Johnson, Egil, Kure, Elin H, Vogel, Lotte K

“…Compromised epithelial barriers are found in dysplastic tissue of the gastrointestinal tract. Claudins are transmembrane proteins important for tight…”
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Feasibility of a physical activity intervention during and shortly after chemotherapy for testicular cancer by Thorsen, Lene, Kirkegaard, Camilla, Loge, Jon Håvard, Kiserud, Cecilie E, Johansen, Merethe Lia, Gjerset, Gunhild M, Edvardsen, Elisabeth, Hamre, Hanne, Ikdahl, Tone, Fosså, Sophie D

“…Given the risk of developing acute and long-term adverse effects in patients receiving cisplatin-based chemotherapy for testicular cancer (TC), risk-reducing…”
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Plasma YKL-40 in patients with metastatic colorectal cancer treated with first line oxaliplatin-based regimen with or without cetuximab: RESULTS from the NORDIC VII Study by Tarpgaard, Line S, Guren, Tormod K, Glimelius, Bengt, Christensen, Ib J, Pfeiffer, Per, Kure, Elin H, Sorbye, Halfdan, Ikdahl, Tone, Yilmaz, Mette, Johansen, Julia S, Tveit, Kjell Magne

“…We aim to test the hypothesis that high plasma YKL-40 is associated with short progression-free survival (PFS) and overall survival (OS) in patients with…”
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Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma by Lorentzen, Anders, Vogel, Lotte K, Lewinsky, Rikke H, Saebø, Mona, Skjelbred, Camilla F, Godiksen, Sine, Hoff, Geir, Tveit, Kjell M, Lothe, Inger Marie Bowitz, Ikdahl, Tone, Kure, Elin H, Mitchelmore, Cathy

“…It has recently been shown that NDRG2 mRNA is down-regulated or undetectable in several human cancers and cancer cell-lines. Although the function of NDRG2 is…”
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TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer by Tarpgaard, Line S, Ørum-Madsen, Maj Sofie, Christensen, Ib J, Nordgaard, Cathrine, Noer, Julie, Guren, Tormod K, Glimelius, Bengt, Sorbye, Halfdan, Ikdahl, Tone, Kure, Elin H, Tveit, Kjell M, Nielsen, Hans J, Pfeiffer, Per, Brünner, Nils, Moreira, José M A

“…It is now widely accepted that therapeutic antibodies targeting epidermal growth factor receptor (EGFR) can have efficacy in KRAS wild-type advanced colorectal…”
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TP53mutation status and gene expression profiles are powerful prognostic markers of breast cancer by Langerad, Anita, Zhao, Hongjuan, Borgan, Ørnulf, Nesland, Jahn M, Bukholm, Ida RK, Ikdahl, Tone, KÃ¥resen, Rolf, Barresen-Dale, Anne-Lise, Jeffrey, Stefanie S

“…Abstract Introduction Gene expression profiling of breast carcinomas has increased our understanding of the heterogeneous biology of this disease and promises…”
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Comparing Two Classifications of Cancer Cachexia and Their Association with Survival in Patients with Unresected Pancreatic Cancer by Wesseltoft-Rao, Nima, Hjermstad, Marianne J., Ikdahl, Tone, Dajani, Olav, Ulven, Stine M., Iversen, Per Ole, Bye, Asta

“…There is no universally accepted definition of cancer cachexia. Two classifications have been proposed; the 3-factor classification requiring ≥2 of 3 factors;…”
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TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer by Langerød, Anita, Zhao, Hongjuan, Borgan, Ørnulf, Nesland, Jahn M, Bukholm, Ida R K, Ikdahl, Tone, Kåresen, Rolf, Børresen-Dale, Anne-Lise, Jeffrey, Stefanie S

“…Gene expression profiling of breast carcinomas has increased our understanding of the heterogeneous biology of this disease and promises to impact clinical…”
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The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma by Sandhu, Vandana, Wedge, David C, Bowitz Lothe, Inger Marie, Labori, Knut Jørgen, Dentro, Stefan C, Buanes, Trond, Skrede, Martina L, Dalsgaard, Astrid M, Munthe, Else, Myklebost, Ola, Lingjærde, Ole Christian, Børresen-Dale, Anne-Lise, Ikdahl, Tone, Van Loo, Peter, Nord, Silje, Kure, Elin H

“…Despite advances in diagnostics, less than 5% of patients with periampullary tumors experience an overall survival of five years or more. Periampullary tumors…”
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Screening for germ line TP53 mutations in breast cancer patients by BØRRESEN, A.-L, ANDERSEN, T. I, FRIEND, S. H, GARBER, J, BARBIER-PIRAUX, N, THORLACIUS, S, EYFJÖRD, J, OTTESTAD, L, SMITH-SØRENSEN, B, HOVIG, E, MALKIN, D

“…The constant denaturant gel electrophoresis technique was used to screen for TP53 germ line mutations in 237 women with breast carcinoma (167 unselected…”
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FCGR2A and FCGR3A polymorphisms and clinical outcome in metastatic colorectal cancer patients treated with first-line 5-fluorouracil/folinic acid and oxaliplatin +/- cetuximab by Kjersem, Janne B, Skovlund, Eva, Ikdahl, Tone, Guren, Tormod, Kersten, Christian, Dalsgaard, Astrid M, Yilmaz, Mette K, Fokstuen, Tone, Tveit, Kjell M, Kure, Elin H

“…Polymorphisms of genes encoding the Fcy receptors (Fc fragment of IgG receptor 2A (FCGR2A) and 3A (FCGR3A)), which influence their affinity for the Fc…”
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Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab by Kjersem, Janne B, Ikdahl, Tone, Guren, Tormod, Skovlund, Eva, Sorbye, Halfdan, Hamfjord, Julian, Pfeiffer, Per, Glimelius, Bengt, Kersten, Christian, Solvang, Hiroko, Tveit, Kjell M, Kure, Elin H

“…Recent studies have reported associations between a variant allele in a let-7 microRNA complementary site (LCS6) within the 3'untranslated region (3'UTR) of…”
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C-reactive protein and interleukin-6 as markers of systemic inflammatory response and as prognostic factors for metastatic colorectal cancer. Data from the randomized phase III NORDIC-VII study by Thomsen, Maria, Kersten, Christian, Sorbye, Halfdan, Skovlund, Eva, Ikdahl, Tone, Johansen, Julia S., Pfeiffer, Per, Glimelius, Bengt, Tveit, Kjell Magne, Guren, Tormod Kyrre

“…Abstract only…”
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Screening for ESR mutations in breast and ovarian cancer patients by Andersen, Tone Ikdahl, Wooster, Richard, Laake, Kirsten, Collins, Nadine, Warren, William, Skrede, Martina, Eeles, Rose, Tveit, Kjell M., Johnston, Stephen R. D., Dowsett, Mitchell, Olsen, Anne O., Møller, Pål, Stratton, Mike R., Børresen-Dale, Anne-Lise

“…In the present study, leukocyte DNA from 143 patients with familial clustering of breast and/or ovarian cancer and tumour DNA from 96 breast carcinomas were…”
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