Search Results - "Ijzerman, M. Marian"
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A phase 1 study of nevanimibe HCl, a novel adrenal-specific sterol O-acyltransferase 1 (SOAT1) inhibitor, in adrenocortical carcinoma
Published in Investigational new drugs (01-10-2020)“…Summary Background Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with very limited treatment options. Nevanimibe HCl (formerly ATR-101), a…”
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Complicated Skin and Skin-Structure Infections and Catheter-Related Bloodstream Infections: Noninferiority of Linezolid in a Phase 3 Study
Published in Clinical infectious diseases (15-01-2009)“…Background.Catheter-related bloodstream infection (CRBSI) causes substantial morbidity and mortality, but few randomized, controlled studies have been…”
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Combined retrospective analysis of seven phase II and III trials of the efficacy of linezolid in the treatment of pneumonia caused by multidrug-resistant Streptococcus pneumoniae
Published in Clinical therapeutics (01-12-2010)“…Abstract Background: Antimicrobial resistance among Streptococcus pneumoniae is of concern. Up to 30% of pneumococcal isolates worldwide are multidrug…”
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Field Evaluation of Two Colorimetric Coliphage Detection Methods
Published in Applied and Environmental Microbiology (01-03-1994)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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SUN-357 Trial in Progress: A Multicenter, Dose-titration, Open-Label Phase 2b Study of Nevanimibe Hydrochloride, a Novel ACAT1 Inhibitor, for the Treatment of Classic Congenital Adrenal Hyperplasia
Published in Journal of the Endocrine Society (30-04-2019)“…More than 90% of classic congenital adrenal hyperplasia (CAH) patients have defects in the cytochrome P450 enzyme steroid 21-hydroxylase, resulting in the…”
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A method to remove environmental inhibitors prior to the detection of waterborne enteric viruses by reverse transcription-polymerase chain reaction
Published in Journal of virological methods (1997)“…A method was developed to remove environmental inhibitors from sample concentrates prior to detection of human enteric viruses using the reverse…”
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Fecal indicator organisms below an on-site wastewater system with low pressure distribution
Published in Water, air, and soil pollution (01-05-1992)“…The low pressure distribution (LPD) of wastewater in shallow soil, made necessary by restricted soil horizons, was evaluated in 4 subsystems with loading rates…”
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Improved method for coliphage detection based on beta-galactosidase induction
Published in Journal of virological methods (01-10-1992)“…An improved method for coliphage detection based on the induction of beta-galactosidase in Escherichia coli is described. Upon infection by coliphages, the…”
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A liquid, colorimetric presence-absence coliphage detection method
Published in Journal of virological methods (15-12-1993)“…A liquid, colorimetric presence-absence coliphage detection method based on the induction of beta-galactosidase by Escherichia coli is described. The release…”
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