Search Results - "Ijiri, Takashi W"
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DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes
Published in Genes & development (01-04-2008)“…Silencing of transposable elements occurs during fetal gametogenesis in males via de novo DNA methylation of their regulatory regions. The loss of MILI…”
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Mili, a mammalian member of piwi family gene, is essential for spermatogenesis
Published in Development (Cambridge) (01-02-2004)“…The piwi family genes, which are defined by conserved PAZ and Piwi domains, play important roles in stem cell self-renewal, RNA silencing, and translational…”
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The egg membrane microdomain-associated uroplakin III-Src system becomes functional during oocyte maturation and is required for bidirectional gamete signaling at fertilization in Xenopus laevis
Published in Development (Cambridge) (15-04-2014)“…In Xenopus laevis, sperm-egg interaction promotes partial proteolysis and/or tyrosine phosphorylation of uroplakin III (UPIII) and the tyrosine kinase Src,…”
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Male mice express spermatogenic cell-specific triosephosphate isomerase isozymes
Published in Molecular reproduction and development (01-10-2013)“…SUMMARY Triosephosphate isomerase 1 (TPI1) is a member of the glycolytic pathway, which is a critical source of energy for motility in mouse sperm. By…”
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Identification and validation of mouse sperm proteins correlated with epididymal maturation
Published in Proteomics (Weinheim) (01-10-2011)“…Sperm need to mature in the epididymis to become capable of fertilization. To understand the molecular mechanisms of mouse sperm maturation, we conducted a…”
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Heads or tails? Structural events and molecular mechanisms that promote mammalian sperm acrosomal exocytosis and motility
Published in Molecular reproduction and development (01-01-2012)“…Sperm structure has evolved to be very compact and compartmentalized to enable the motor (the flagellum) to transport the nuclear cargo (the head) to the egg…”
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Protein-Tyrosine Kinase Signaling in the Biological Functions Associated with Sperm
Published in Journal of Signal Transduction (01-01-2012)“…In sexual reproduction, two gamete cells (i.e., egg and sperm) fuse (fertilization) to create a newborn with a genetic identity distinct from those of the…”
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The need of MMP-2 on the sperm surface for Xenopus fertilization: Its role in a fast electrical block to polyspermy
Published in Mechanisms of development (01-11-2014)“…•We examine the role of MMP-2 on the sperm membrane upon frog fertilization.•Enzymatic activity of MMP-2 is necessary for fertilization of jellied eggs.•A…”
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Isolation and characterization of novel testis‐specific genes from mouse pachytene spermatocyte‐enriched cDNA library
Published in Reproductive medicine and biology (01-12-2005)“…Background and Aims: Isolation and analysis of spermatogenesis‐specific genes provide important information for elucidating the mechanisms of human…”
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Characterization of a Novel Tektin Member, TEKT5, in Mouse Sperm
Published in Journal of andrology (01-01-2011)“…Tektins are important components of flagella. Alterations in the expression of or mutations in mouse tektins are correlated with defective sperm motility, a…”
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Original Article: Isolation and characterization of novel testis-specific genes from mouse pachytene spermatocyte-enriched cDNA library
Published in Reproductive medicine and biology (01-12-2005)“…Background and Aims:Isolation and analysis of spermatogenesis-specific genes provide important information for elucidating the mechanisms of human infertility…”
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12
Involvement of Src in the Adaptation of Cancer Cells under Microenvironmental Stresses
Published in Journal of Signal Transduction (01-01-2012)“…Protein-tyrosine phosphorylation, which is catalyzed by protein-tyrosine kinase (PTK), plays a pivotal role in a variety of cellular functions related to…”
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