Search Results - "Iijima, Mikio"
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Wnt‐5a signaling is correlated with infiltrative activity in human glioma by inducing cellular migration and MMP‐2
Published in Cancer science (01-03-2011)“…Wnts are secreted ligands that consist of 19 members in humans, regulate cell proliferation, differentiation, motility and fate in many stages including the…”
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Intercellular signaling between ameloblastoma and osteoblasts
Published in Biochemistry and biophysics reports (01-07-2022)“…Ameloblastoma is an odontogenic tumor located in the bone jaw with clinical characteristics of extensive bone resorption. It is a locally invasive tumor with a…”
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Identification of 13 novel mutations including a retrotransposal insertion in SLC25A13 gene and frequency of 30 mutations found in patients with citrin deficiency
Published in Journal of human genetics (01-06-2008)“…Deficiency of citrin, liver-type mitochondrial aspartate-glutamate carrier, is an autosomal recessive disorder caused by mutations of the SLC25A13 gene on…”
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Essential Role of Aralar in the Transduction of Small Ca+ Signals to Neuronal Mitochondria
Published in The Journal of biological chemistry (13-01-2006)“…Aralar, the neuronal Ca2+-binding mitochondrial aspartate-glutamate carrier, has Ca2+ binding domains facing the extramitochondrial space and functions in the…”
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5
Subcellular localization and putative role of VPS13A/chorein in dopaminergic neuronal cells
Published in Biochemical and biophysical research communications (16-03-2012)“…► Chorein was partially colocalized with Synaptotagmin I in PC12 cells. ► Chorein was localized to dense-core vesicle in mouse brain and PC12 cells. ►…”
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A novel ameloblastoma cell line (AM-3) secretes MMP-9 in response to Wnt-3a and induces osteoclastogenesis
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-06-2013)“…Objective Ameloblastoma has a high risk of bone invasion and local recurrence. However, the mechanisms of bone invasion in ameloblastoma remain unclear. In…”
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Reduced N-Acetylaspartate Levels in Mice Lacking Aralar, a Brain- and Muscle-type Mitochondrial Aspartate-glutamate Carrier
Published in The Journal of biological chemistry (02-09-2005)“…Aralar is a mitochondrial calcium-regulated aspartate-glutamate carrier mainly distributed in brain and skeletal muscle, involved in the transport of aspartate…”
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Citrin/Mitochondrial Glycerol-3-phosphate Dehydrogenase Double Knock-out Mice Recapitulate Features of Human Citrin Deficiency
Published in The Journal of biological chemistry (24-08-2007)“…Citrin is the liver-type mitochondrial aspartate-glutamate carrier that participates in urea, protein, and nucleotide biosynthetic pathways by supplying…”
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Frequency and distribution in East Asia of 12 mutations identified in the SLC25A13 gene of Japanese patients with citrin deficiency
Published in Journal of human genetics (01-07-2005)“…Deficiency of citrin, a liver-type mitochondrial aspartate-glutamate carrier (AGC), encoded by the SLC25A13 gene on chromosome 7q21.3, causes autosomal…”
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10
Fasting-induced reduction in locomotor activity and reduced response of orexin neurons in carnitine-deficient mice
Published in Neuroscience research (01-05-2006)“…We found reduced locomotor activity (LA) under fasting in systemic carnitine-deficient juvenile visceral steatosis ( jvs −/−) mice. When food was withdrawn at…”
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Adult-onset type II citrullinemia and idiopathic neonatal hepatitis caused by citrin deficiency: involvement of the aspartate glutamate carrier for urea synthesis and maintenance of the urea cycle
Published in Molecular genetics and metabolism (01-04-2004)“…Citrin is a mitochondrial aspartate glutamate carrier primarily expressed in the liver, heart, and kidney. We found that adult-onset type II citrullinemia is…”
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12
Immortalization and characterization of normal oral epithelial cells without using HPV and SV40 genes
Published in Oral science international (01-05-2011)“…As oral neoplasm often originates from epithelium, an immortalized epithelial cell line could be useful for the research of oral carcinogenesis. Although…”
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Slc25a13-Knockout Mice Harbor Metabolic Deficits but Fail To Display Hallmarks of Adult-Onset Type II Citrullinemia
Published in Molecular and Cellular Biology (01-01-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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14
Pyruvate ameliorates the defect in ureogenesis from ammonia in citrin-deficient mice
Published in Journal of hepatology (01-05-2006)“…Mutations in SLC25A13, encoding the mitochondrial aspartate-glutamate carrier citrin, cause adult-onset type II citrullinemia (CTLN2) in humans. We have…”
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Novel diagnostic approach to citrin deficiency: Analysis of citrin protein in lymphocytes
Published in Molecular genetics and metabolism (2007)“…Citrin deficiency induces two clinical features; namely neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) and adult-onset type II…”
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Ryk is essential for Wnt-5a-dependent invasiveness in human glioma
Published in Journal of biochemistry (Tokyo) (01-07-2014)Get full text
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The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein
Published in Nature genetics (01-06-1999)Get full text
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Ca2+ Activation Kinetics of the Two Aspartate-Glutamate Mitochondrial Carriers, Aralar and Citrin
Published in The Journal of biological chemistry (09-03-2007)“…Ca2+ regulation of the Ca2+ binding mitochondrial carriers for aspartate/glutamate (AGCs) is provided by their N-terminal extensions, which face the…”
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Pathogenesis and pathophysiology of citrin (a mitochondrial aspartate glutamate carrier) deficiency
Published in Metabolic brain disease (01-12-2002)“…Adult-onset type II citrullinemia (CTLN2), characterized by a liver-specific deficiency of urea cycle enzyme, argininosuccinate synthetase, is caused by…”
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Ca²⁺ Activation Kinetics of the Two Aspartate-Glutamate Mitochondrial Carriers, Aralar and Citrin: ROLE IN THE HEART MALATE-ASPARTATE NADH SHUTTLE
Published in The Journal of biological chemistry (09-03-2007)“…Ca²⁺ regulation of the Ca²⁺ binding mitochondrial carriers for aspartate/glutamate (AGCs) is provided by their N-terminal extensions, which face the…”
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