Search Results - "Ihara, Fumiaki"
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Correction: Transcriptional profiling of Toll-like receptor 2-deficient primary murine brain cells during Toxoplasma gondii infection
Published in PloS one (02-05-2024)“…[This corrects the article DOI: 10.1371/journal.pone.0187703.]…”
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Transcriptome Analysis of Mouse Brain Infected with Toxoplasma gondii
Published in Infection and Immunity (01-10-2013)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Neospora caninum Dense Granule Protein 7 Regulates the Pathogenesis of Neosporosis by Modulating Host Immune Response
Published in Applied and environmental microbiology (15-09-2018)“…is a protozoan parasite closely related to Neosporosis caused by is considered one of the main causes of abortion in cattle and nervous-system dysfunction in…”
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Toxoplasma gondii Dense Granule Proteins 7, 14, and 15 Are Involved in Modification and Control of the Immune Response Mediated via NF-κB Pathway
Published in Frontiers in immunology (31-07-2020)“…infects almost all warm-blooded animals, including humans, leading to both cellular and humoral immune responses in the host. The virulence of is strain…”
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Toxoplasma gondii Infection in Mice Impairs Long-Term Fear Memory Consolidation through Dysfunction of the Cortex and Amygdala
Published in Infection and immunity (01-10-2016)“…Chronic infection with Toxoplasma gondii becomes established in tissues of the central nervous system, where parasites may directly or indirectly modulate…”
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Induction of depression-related behaviors by reactivation of chronic Toxoplasma gondii infection in mice
Published in Behavioural brain research (01-02-2016)“…•Induction of depressive-like behaviors following reactivation of T. gondii.•Upregulated IFN-γ and brain indoleamine 2,3-dioxygenase in reactivated T…”
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Far-East Asian Toxoplasma isolates share ancestry with North and South/Central American recombinant lineages
Published in Nature communications (22-05-2024)“…Toxoplasma gondii is a global protozoan pathogen. Clonal lineages predominate in Europe, North America, Africa, and China, whereas highly recombinant parasites…”
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Involvement of Toll-like receptor 2 in the cerebral immune response and behavioral changes caused by latent Toxoplasma infection in mice
Published in PloS one (12-08-2019)“…Subacute and chronic infections with the intracellular protozoan parasite Toxoplasma gondii are associated with an increased risk of psychiatric diseases like…”
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Transcriptome analysis of the effect of C-C chemokine receptor 5 deficiency on cell response to Toxoplasma gondii in brain cells
Published in BMC genomics (11-09-2019)“…Infection with Toxoplasma gondii is thought to damage the brain and be a risk factor for neurological and psychotic disorders. The immune…”
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Transcriptional profiling of Toll-like receptor 2-deficient primary murine brain cells during Toxoplasma gondii infection
Published in PloS one (14-11-2017)“…Toxoplasma gondii is capable of persisting in the brain, although it is efficiently eliminated by cellular immune responses in most other sites. While…”
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Macrophage depletion prior to Neospora caninum infection results in severe neosporosis in mice
Published in Clinical and vaccine immunology (01-08-2014)“…We observed that murine macrophages showed greater activation and increased interleukin 6 (IL-6), IL-12p40, and interferon gamma (IFN-γ) production during…”
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Starvation of low-density lipoprotein-derived cholesterol induces bradyzoite conversion in Toxoplasma gondii
Published in Parasites & vectors (29-05-2014)“…BACKGROUND: Lacking enzymes for sterol synthesis, the intracellular protozoan Toxoplasma gondii scavenges cholesterol from host cells to multiply. T. gondii…”
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Transcriptomic Analysis of the Effects of Chemokine Receptor CXCR3 Deficiency on Immune Responses in the Mouse Brain during Toxoplasma gondii Infection
Published in Microorganisms (Basel) (12-11-2021)“…The obligate intracellular parasite Toxoplasma gondii infects warm-blooded animals, including humans. We previously revealed through a whole-brain…”
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Role of the chemokine receptor CCR5-dependent host defense system in Neospora caninum infections
Published in Parasites & vectors (06-01-2015)“…BACKGROUND: Neospora caninum, a Toxoplasma gondii-like obligate intracellular parasite, causes abortion in cattle and neurological signs in canines. To…”
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The role of IFN-γ-mediated host immune responses in monitoring and the elimination of Toxoplasma gondii infection
Published in International immunology (03-04-2024)“…Toxoplasma gondii is a pathogenic protozoan parasite of the Apicomplexa family that affects approximately 30% of the world's population. Symptoms are usually…”
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Toxoplasma gondii manipulates host cell signaling pathways via its secreted effector molecules
Published in Parasitology international (01-08-2021)“…The obligate intracellular parasite Toxoplasma gondii secretes a vast variety of effector molecules from organelles known as rhoptries (ROPs) and dense…”
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Toxoplasma GRA15 expression on dendritic cells inhibits B cell differentiation and antibody production
Published in Parasitology international (16-11-2024)“…One of the dense granule proteins named GRA15 in Toxoplasma gondii (T. gondii), is known to support an innate immune response in host through activation of…”
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Vaccination with profilin encapsulated in oligomannose-coated liposomes induces significant protective immunity against Toxoplasma gondii
Published in Vaccine (01-04-2014)“…Highlights • We confirmed the immunogenicity of TgPF in mice after Toxoplasma gondii infection. • TgPF-OML administration increased the survival of mice after…”
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Development and evaluation of the first immunochromatographic test that can detect specific antibodies against Cryptosporidium parvum
Published in Acta tropica (01-09-2018)“…Cryptosporidium parvum is a major cause of diarrhea among human and calves, resulting in severe health hazards and drastic economic losses, respectively…”
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Changes in neurotransmitter levels and expression of immediate early genes in brain of mice infected with Neospora caninum
Published in Scientific reports (14-03-2016)“…Neospora caninum is an obligate intracellular parasite that causes neurological disorders in dogs and cattle. The majority of host animals are asymptomatic at…”
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