Search Results - "Igor Kovalchuk"

Role of Epigenetic Factors in Response to Stress and Establishment of Somatic Memory of Stress Exposure in Plants by Kovalchuk, Igor

“…All species are well adapted to their environment. Stress causes a magnitude of biochemical and molecular responses in plants, leading to physiological or…”
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Heritable responses to stress in plants by Kovalchuk, Igor

“…Most plants are adapted to their environments through generations of exposure to all elements. The adaptation process involves the best possible response to…”
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Transgenerational response to stress in plants and its application for breeding by Bilichak, Andriy, Kovalchuk, Igor

“…A growing number of reports indicate that plants possess the ability to maintain a memory of stress exposure throughout their ontogenesis and even transmit it…”
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The Role of microRNAs in Organismal and Skin Aging by Gerasymchuk, Marta, Cherkasova, Viktoriia, Kovalchuk, Olga, Kovalchuk, Igor

“…The aging process starts directly after birth and lasts for the entire lifespan; it manifests itself with a decline in an organism's ability to adapt and is…”
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Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health by Babenko, Olena, Kovalchuk, Igor, Metz, Gerlinde A S

“…Research efforts during the past decades have provided intriguing evidence suggesting that stressful experiences during pregnancy exert long-term consequences…”
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The progeny of Arabidopsis thaliana plants exposed to salt exhibit changes in DNA methylation, histone modifications and gene expression by Bilichak, Andriy, Ilnystkyy, Yaroslav, Hollunder, Jens, Kovalchuk, Igor

“…Plants are able to acclimate to new growth conditions on a relatively short time-scale. Recently, we showed that the progeny of plants exposed to various…”
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Epigenetic Regulation of Cellular Senescence and Aging by Sidler, Corinne, Kovalchuk, Olga, Kovalchuk, Igor

“…Aging is characterized by functional decline of diverse organs and an increased risk for several diseases. Therefore, a high interest exists in understanding…”
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Epigenetic control of plant stress response by Boyko, Alex, Kovalchuk, Igor

“…Living organisms have the clearly defined strategies of stress response. These strategies are predefined by a genetic make-up of the organism and depend on a…”
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Targeting Colorectal Cancer: Unravelling the Transcriptomic Impact of Cisplatin and High-THC Cannabis Extract by Cherkasova, Viktoriia, Ilnytskyy, Yaroslav, Kovalchuk, Olga, Kovalchuk, Igor

“…Cisplatin and other platinum-derived chemotherapy drugs have been used for the treatment of cancer for a long time and are often combined with other…”
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Transcriptome Analysis of Cisplatin, Cannabidiol, and Intermittent Serum Starvation Alone and in Various Combinations on Colorectal Cancer Cells by Cherkasova, Viktoriia, Ilnytskyy, Yaroslav, Kovalchuk, Olga, Kovalchuk, Igor

“…Platinum-derived chemotherapy medications are often combined with other conventional therapies for treating different tumors, including colorectal cancer…”
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Cannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective by Suryavanshi, Santosh V, Kovalchuk, Igor, Kovalchuk, Olga

“…Inflammasomes are cytoplasmic inflammatory signaling protein complexes that detect microbial materials, sterile inflammatory insults, and certain host-derived…”
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Modeling of the Senescence-Associated Phenotype in Human Skin Fibroblasts by Gerasymchuk, Marta, Robinson, Gregory Ian, Kovalchuk, Olga, Kovalchuk, Igor

“…Modern understanding of aging is based on the accumulation of cellular damage during one’s life span due to the gradual deterioration of regenerative…”
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The Effects of Nutrient Signaling Regulators in Combination with Phytocannabinoids on the Senescence-Associated Phenotype in Human Dermal Fibroblasts by Gerasymchuk, Marta, Robinson, Gregory Ian, Kovalchuk, Olga, Kovalchuk, Igor

“…Identifying effective anti-aging compounds is a cornerstone of modern longevity, aging, and skin-health research. There is considerable evidence of the…”
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The Anti-Inflammatory Effects of Cannabis sativa Extracts on LPS-Induced Cytokines Release in Human Macrophages by Zaiachuk, Mariia, Suryavanshi, Santosh V, Pryimak, Nazar, Kovalchuk, Igor, Kovalchuk, Olga

“…Inflammation is the response of the innate immune system to any type of injury. Although acute inflammation is critical for survival, dysregulation of the…”
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Analysis of Anti-Cancer and Anti-Inflammatory Properties of 25 High-THC Cannabis Extracts by Li, Dongping, Ilnytskyy, Yaroslav, Ghasemi Gojani, Esmaeel, Kovalchuk, Olga, Kovalchuk, Igor

“…is one of the oldest cultivated plants. Many of the medicinal properties of cannabis are known, although very few cannabis-based formulations became prescribed…”
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Genetic and Epigenetic Effects of Plant-Pathogen Interactions： An Evolutionary Perspective by Boyko, Alex, Kovalchuk, Igor

“…Recent reports suggest that exposure to stress is capable of influencing the frequency and pattern of inherited changes in various parts of the genome. In this…”
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Genomic and Epigenomic Changes in the Progeny of Cold-Stressed Arabidopsis thaliana Plants by Rahman, Ashif, Yadav, Narendra Singh, Byeon, Boseon, Ilnytskyy, Yaroslav, Kovalchuk, Igor

“…Plants are continuously exposed to various environmental stresses. Because they can not escape stress, they have to develop mechanisms of remembering stress…”
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Transgenerational adaptation of Arabidopsis to stress requires DNA methylation and the function of Dicer-like proteins by Boyko, Alex, Blevins, Todd, Yao, Youli, Golubov, Andrey, Bilichak, Andriy, Ilnytskyy, Yaroslav, Hollunder, Jens, Hollander, Jens, Meins, Jr, Frederick, Kovalchuk, Igor

“…Epigenetic states and certain environmental responses in mammals and seed plants can persist in the next sexual generation. These transgenerational effects…”
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Ancestral Stress Alters Lifetime Mental Health Trajectories and Cortical Neuromorphology via Epigenetic Regulation by Ambeskovic, Mirela, Babenko, Olena, Ilnytskyy, Yaroslav, Kovalchuk, Igor, Kolb, Bryan, Metz, Gerlinde A. S.

“…Experiences during early development are powerful determinants of lifetime mental health. Here we investigated if ancestral stress regulates the brain’s…”
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Anti-Inflammatory Effects of Minor Cannabinoids CBC, THCV, and CBN in Human Macrophages by Gojani, Esmaeel Ghasemi, Wang, Bo, Li, Dong-Ping, Kovalchuk, Olga, Kovalchuk, Igor

“…Inflammation is a natural response of the body to signals of tissue damage or infection caused by pathogens. However, when it becomes imbalanced, it can lead…”
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