Search Results - "Ignatowicz, L"

EFFORT OF STEEL PIPE JACKING IN TERMS OF IMPERFECTION PIPES AND HETEROGENEITY OF GROUND by Górski, K., Ignatowicz, R. L.

“…Purpose. The article presents problem of the influence of local inhomogeneities of ground on the internal forces in the steel pipe. Methodology. The authors…”
Get full text

Detection of apoptosis of immature CD4+8+ thymocytes by flow cytometry by Swat, W, Ignatowicz, L, Kisielow, P

“…Apoptosis, i.e., programmed cell death, may be the mechanism by which both autoreactive and unselected immature CD4+8+ thymocytes are eliminated in the thymus…”
Get more information

Alpha beta TCRs differ in the degree of their specificity for the positively selecting MHC/peptide ligand by Kraj, P, Pacholczyk, R, Ignatowicz, L

“…We have tested the peptide specificity of positive selection using three transgenic alphabetaTCRs, originally selected on class II MHC (A(b)) covalently bound…”
Get full text

Positive selection of CD4(+) T cells is induced in vivo by agonist and inhibited by antagonist peptides by Kraj, P, Pacholczyk, R, Ignatowicz, H, Kisielow, P, Jensen, P, Ignatowicz, L

“…The nature of peptides that positively select T cells in the thymus remains poorly defined. Here we report an in vivo model to study the mechanisms of positive…”
Get full text

Cell surface expression of class II MHC proteins bound by a single peptide by Ignatowicz, L, Winslow, G, Bill, J, Kappler, J, Marrack, P

“…On normal cells, the peptide-binding grooves of class II MHC proteins contain a wide spectrum of peptides. For some purposes, however, it would be helpful to…”
Get full text

The effects of chronic infection with a superantigen-producing virus by IGNATOWICZ, L, KAPPLER, J, MARRACK, P

“…C3H/HeJ mice transmit a mouse mammary tumor virus from mother to pup in milk. The retrovirus infects mice shortly after birth and, when expressed in recipient…”
Get full text

Synthesis of an Immunologically Active Heptamannoside of Mycobacterium tuberculosis by the [Au]/[Ag]-Catalyzed Activation of Ethynylcyclohexyl Glycosyl Carbonate Donor by Shinde, Ganesh P., Sutar, Yogesh, Kasdekar, Niteshlal, Joshi, Pooja, Rasool, Omid, Ignatowicz, Lech, Hamasur, Beston, Hotha, Srinivas

“…Tuberculosis (TB) is one of the most dreadful diseases, killing more than 3 million humans annually. M. tuberculosis (MTb) is the causative agent for TB and…”
Get full text

Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties? by Moll, Guido, Alm, Jessica J., Davies, Lindsay C., von Bahr, Lena, Heldring, Nina, Stenbeck‐Funke, Lillemor, Hamad, Osama A., Hinsch, Robin, Ignatowicz, Lech, Locke, Matthew, Lönnies, Helena, Lambris, John D., Teramura, Yuji, Nilsson‐Ekdahl, Kristina, Nilsson, Bo, Blanc, Katarina

“…We have recently reported that therapeutic mesenchymal stromal cells (MSCs) have low engraftment and trigger the instant blood mediated inflammatory reaction…”
Get full text

Different Procoagulant Activity of Therapeutic Mesenchymal Stromal Cells Derived from Bone Marrow and Placental Decidua by Moll, Guido, Ignatowicz, Lech, Catar, Rusan, Luecht, Christian, Sadeghi, Behnam, Hamad, Osama, Jungebluth, Philipp, Dragun, Duska, Schmidtchen, Artur, Ringdén, Olle

“…While therapeutic mesenchymal stromal/stem cells (MSCs) have usually been obtained from bone marrow, perinatal tissues have emerged as promising new sources of…”
Get more information

Altered Selection of CD4+ T Cells by Class II MHC Bound with Dominant and Low Abundance Self-Peptides by Gaszewska-Mastalarz, Anna, Muranski, Pawel, Chmielowski, Bartosz, Kraj, Piotr, Ignatowicz, Leszek

“…We have investigated the development of CD4(+) T cells in mice expressing low levels of transgenic class II MHC molecules (A(b)) preoccupied with covalent…”
Get full text

Failure To Recruit Anti-Inflammatory CD103+ Dendritic Cells and a Diminished CD4+ Foxp3+ Regulatory T Cell Pool in Mice That Display Excessive Lung Inflammation and Increased Susceptibility to Mycobacterium tuberculosis by LEEPIYASAKULCHAI, Chaniya, IGNATOWICZ, Lech, PAWLOWSKI, Andrzej, KÄLLENIUS, Gunilla, SKÖLD, Markus

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Effects of Freeze-Thawing and Intravenous Infusion on Mesenchymal Stromal Cell Gene Expression by Hoogduijn, Martin J, de Witte, Samantha F H, Luk, Franka, van den Hout-van Vroonhoven, Mirjam C G N, Ignatowicz, Lech, Catar, Rusan, Strini, Tanja, Korevaar, Sander S, van IJcken, Wilfred F J, Betjes, Michiel G H, Franquesa, Marcella, Moll, Guido, Baan, Carla C

“…Mesenchymal stromal cells (MSC) are increasingly used as an investigative therapeutic product for immune disorders and degenerative disease. Typically, MSC are…”
Get more information

Field evaluation of a prototype tuberculosis lipoarabinomannan lateral flow assay on HIV-positive and HIV-negative patients by Connelly, John T, Andama, Alfred, Grant, Benjamin D, Ball, Alexey, Mwebe, Sandra, Asege, Lucy, Nakaye, Martha, Lopez, Brianda Barrios, Hsieh, Helen V, Katumba, David, Mukwatamundu, Job, Nalubega, Mayimuna, Hunt, Victoria M, Burkot, Stephen, Ramachandraiah, Harisha, Choudhary, Alok, Ignatowicz, Lech, Weigl, Bernhard H, Bachman, Christine, Mulondo, Jerry, Semitala, Fred, Worodria, William, Pinter, Abraham, Hamasur, Beston, Bell, David, Cattamanchi, Adithya, Somoskovi, Akos

“…Detection of tuberculosis at the point-of-care (POC) is limited by the low sensitivity of current commercially available tests. We describe a diagnostic…”
Get full text

Divergent effects of mycobacterial cell wall glycolipids on maturation and function of human monocyte-derived dendritic cells by Mazurek, Jolanta, Ignatowicz, Lech, Kallenius, Gunilla, Svenson, Stefan B, Pawlowski, Andrzej, Hamasur, Beston

“…Mycobacterium tuberculosis (Mtb) is able to evade the immune defenses and may persist for years, decades and even lifelong in the infected host. Mtb cell wall…”
Get full text

Silencing Suppressor of Cytokine Signaling-1 (SOCS1) in Macrophages Improves Mycobacterium tuberculosis Control in an Interferon-γ (IFN-γ)-dependent Manner by Carow, Berit, qun Ye, Xiang, Gavier-Widén, Dolores, Bhuju, Sabin, Oehlmann, Wulf, Singh, Mahavir, Sköld, Markus, Ignatowicz, Lech, Yoshimura, Akihiko, Wigzell, Hans, Rottenberg, Martin E.

“…Protection against infection with Mycobacterium tuberculosis demands IFN-γ. SOCS1 has been shown to inhibit responses to IFN-γ and might thereby play a central…”
Get full text

The Repertoire of T Cells Shaped by a Single MHC/Peptide Ligand by Ignatowicz, Leszek, Kappler, John, Marrack, Philippa

“…Although the thymus produces many immature thymocytes, few of these cells mature. Positive selection has been thought to limit thymocyte development. In…”
Get full text

Increase in wind load during assembly causes collapse of the hall structure by Ignatowicz, Rajmund L., Gierczak, Jan

“…•The article describes the disaster of a steel hall during assembly.•The wind load during assembly can be higher than the load for an enclosed hall.•The forces…”
Get full text

Mycobacteria‐infected bystander macrophages trigger maturation of dendritic cells and enhance their ability to mediate HIV transinfection by Mazurek, Jolanta, Ignatowicz, Lech, Källenius, Gunilla, Jansson, Marianne, Pawlowski, Andrzej

“…Synergistic interplay between Mycobacterium tuberculosis (Mtb) and HIV in coinfected ind‐ividuals leads to the acceleration of both tuberculosis and…”
Get full text

Peptide Specificity of Thymic Selection of CD4+CD25+ T Cells by Pacholczyk, Rafal, Kraj, Piotr, Ignatowicz, Leszek

“…The CD4(+)CD25(+) regulatory T cells can be found in the thymus, but their need to undergo positive and negative selection has been questioned. Instead, it has…”
Get full text

T cell tolerance. Giles F. Filley Lecture by Marrack, P, McCormack, J, Callahan, J, Ignatowicz, L, Kappler, J

“…T cell tolerance to self is induced by several mechanisms. Immature T cells may die, and mature T cells may die or be inactivated by contact with self. While…”
Get more information