Search Results - "Ignatov, Atanas"
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Endocrine Risk Factors of Endometrial Cancer: Polycystic Ovary Syndrome, Oral Contraceptives, Infertility, Tamoxifen
Published in Cancers (02-07-2020)“…Endometrial cancer is the most common gynecologic cancer and is predominantly endocrine-related. The role of unopposed estrogen in the development of…”
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2
B Cells Induce Early-Onset Maternal Inflammation to Protect against LPS-Induced Fetal Rejection
Published in International journal of molecular sciences (01-11-2023)“…The maternal balance between B regulatory (Breg) cells and inflammatory B cells is of central importance for protection against preterm birth (PTB). However,…”
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3
The 3D in vivo chorioallantoic membrane model and its role in breast cancer research
Published in Journal of cancer research and clinical oncology (01-05-2022)“…Purpose We aimed to evaluate the role of the chorioallantoic membrane model (CAM) in breast cancer research. Methods The following is an overview of the use of…”
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4
Survival benefit of tamoxifen in male breast cancer: prospective cohort analysis
Published in British journal of cancer (07-07-2020)“…Background Due to the lack of prospective data, current treatment of male breast cancer (MBC) is based on information obtained from retrospective analysis or…”
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5
Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells
Published in Breast cancer research and treatment (01-08-2010)“…Tamoxifen is the most frequently used anti-hormonal drug for treatment of women with hormone-dependent breast cancer. The aim of this study is to investigate…”
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GPER-1 expression is associated with a decreased response rate to primary tamoxifen therapy of breast cancer patients
Published in Archives of gynecology and obstetrics (01-02-2020)“…Purpose Endocrine therapies using tamoxifen and/or aromatase inhibitors are important therapeutic options for the targeted treatment of hormone-responsive…”
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7
BCL3 expression is strongly associated with the occurrence of breast cancer relapse under tamoxifen treatment in a retrospective cohort study
Published in Virchows Archiv : an international journal of pathology (01-03-2022)“…Patients with estrogen receptor positive breast cancer are usually receiving an anti-estrogen therapy by either aromatase inhibitors or selective estrogen…”
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G protein-coupled estrogen receptor 1 (GPER-1) and agonist G-1 inhibit growth of ovarian cancer cells by activation of anti-tumoral transcriptome responses: impact of GPER-1 mRNA on survival
Published in Journal of cancer research and clinical oncology (01-12-2020)“…Purpose The present study intended to further elucidate the role of G protein-coupled estrogen receptor 1 (GPER-1) in ovarian cancer by comparing the effects…”
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Minimal-invasive or open approach for surgery of early cervical cancer: the treatment center matters
Published in Archives of gynecology and obstetrics (01-08-2021)“…Purpose The aim of the study was to compare recurrence-free survival (RFS) and overall survival (OS) of patients with early stage cervical cancer in dependence…”
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Adjuvant chemotherapy for breast cancer patients with axillary lymph node micrometastases
Published in Breast cancer research and treatment (01-06-2021)“…Background The axillary lymph node status is one of the most important prognostic factors in patients with early breast cancer. However, the impact of axillary…”
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Diagnosis and treatment of asthma: a guideline for respiratory specialists 2023 - published by the German Respiratory Society (DGP) e. V.
Published in Pneumologie (Stuttgart, Germany) (01-08-2023)“…The management of asthma has fundamentally changed during the past decades. The present guideline for the diagnosis and treatment of asthma was developed for…”
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Tamoxifen treatment for male breast cancer and risk of thromboembolism: prospective cohort analysis
Published in British journal of cancer (05-02-2019)“…Purpose Thromboembolism is a common adverse event in women treated with tamoxifen (TAM) for breast cancer. The risk in male breast cancer patients is poorly…”
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13
Comparison of survival of patients with endometrial cancer undergoing sentinel node biopsy alone or systematic lymphadenectomy
Published in Archives of gynecology and obstetrics (01-10-2020)“…Background Recently, sentinel lymph node mapping was introduced in the surgical staging of endometrial cancer as alternative to systematic lymphadenectomy…”
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Sentinel lymph node detection by means of indocyanine green using the Karl Storz VITOM® fluorescence camera: a comparison between primary sentinel lymph node biopsy versus sentinel lymph node biopsy after neoadjuvant chemotherapy
Published in Journal of cancer research and clinical oncology (01-06-2021)“…Purpose The usage of radioactive Technetium 99m (Tc 99m ) colloid for the purpose of sentinel lymph node biopsy (SLNB) in early breast cancer is considered the…”
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15
Systematic lymphadenectomy in early stage endometrial cancer
Published in Archives of gynecology and obstetrics (01-07-2020)“…Background The positive effect of systematic lymphadenectomy on survival of patients with endometrial cancer is a topic of ongoing debate. Methods We aimed to…”
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Role of Pelvic Lymph Node Resection in Vulvar Squamous Cell Cancer: A Subset Analysis of the AGO-CaRE-1 Study
Published in Annals of surgical oncology (01-10-2021)“…Background As the population at risk for pelvic nodal involvement remains poorly described, the role of pelvic lymphadenectomy (LAE) in vulvar squamous cell…”
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Value of indocyanine green pelvic lymph node mapping in the surgical approach of cervical cancer
Published in Archives of gynecology and obstetrics (01-03-2020)“…Purpose Lymph node metastasis is a significant predictive factor for disease recurrence and survival in cervical cancer patients and relevant for therapeutic…”
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Long-term outcome of patients with intermediate- and high-risk endometrial cancer after pelvic and paraaortic lymph node dissection: a comparison of laparoscopic vs. open procedure
Published in Journal of cancer research and clinical oncology (01-04-2020)“…Objective The primary therapy for intermediate- and high-risk endometrial cancer includes pelvic and paraaortic lymph node evaluation. Laparoscopic surgery is…”
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Is there a benefit for adjuvant radio(chemo)therapy in early cervical cancer? Results from a population-based study
Published in Archives of gynecology and obstetrics (01-09-2021)“…Purpose Due to insufficient and conflicting prospective evidence, the recommendations on when to apply adjuvant radiochemotherapy in early-stage cervical…”
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Factors influencing treatment decision and guideline conformity in high-grade endometrial cancer patients: a population-based study
Published in Archives of gynecology and obstetrics (2022)“…Purpose Treatment according to guidelines has been demonstrated to improve survival in a number of different cancer entities. Deviations from guidelines depend…”
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