Methodology of regional blood stabilization with sodium citrate during hemosorption and the first experience of its clinical application

The method of blood stabilization using sodium citrate ("Glugicir") has been elaborated. The experimental hemosorptions (HS) have shown that reliable blood stabilization in extracorporeal sorption contour was achieved with Glugicir/blood ratio 1 to 10, no considerable changes in the basic...

Full description

Saved in:

Bibliographic Details
Published in:	Anesteziologiia i reanimatologiia no. 6; p. 40
Main Authors:	Egorov, V M, Nazarov, A V, Sentsov, V G, Sukhanov, V A, Ignatenko, T V, Rokin, S R, Amon, E P
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-11-1991
Subjects:	Blood - drug effects Citrates - pharmacology Citric Acid Hemoperfusion - methods Humans Poisoning - therapy
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The method of blood stabilization using sodium citrate ("Glugicir") has been elaborated. The experimental hemosorptions (HS) have shown that reliable blood stabilization in extracorporeal sorption contour was achieved with Glugicir/blood ratio 1 to 10, no considerable changes in the basic clearance characteristics of the sorbents have been observed. The method elaborated was used in 135 HS sessions performed in 100 patients. It has been shown that sodium citrate causes no changes in the patients' hemostasis. The method of regional blood stabilization with sodium citrate may be recommended for HS in patients with bleeding or high risk of its development. Mild symptoms of citrate intoxication (3.7%) were associated with technical inaccuracy and were easily eliminated either by discontinuation of excessive Glugicir introduction into the contour or by intravenous injection of calcium salts.
ISSN:	0201-7563