Search Results - "Iglesias, P A"

A modeling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells by Krishnan, J., Iglesias, P.A.

“…Gradient perception describes the process by which information about the chemoattractant concentration field surrounding a cell is transformed into an internal…”
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A modelling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells II: Input–output analysis by Krishnan, J., Iglesias, P.A.

“…Spatial sensing in Dictyostelium involves localization of the phosphoinositide lipids PI(3,4,5)P 3 and PI(3,4)P 2 at the leading edge of the cell in response…”
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Analysis of the Signal Transduction Properties of a Module of Spatial Sensing in Eukaryotic Chemotaxis by Krishnan, J., Iglesias, P.A.

“…The movement of cells in response to a gradient in chemical concentration—known as chemotaxis—is crucial for the proper functioning of uni- and multicellular…”
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Vehicle lateral control for automated highway systems by O'Brien, R.T., Iglesias, P.A., Urban, T.J.

“…This paper addresses the modeling and control of the lateral motion of a highway vehicle. In particular, a steering controller is designed that tracks the…”
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Models of Eukaryotic Gradient Sensing: Application to Chemotaxis of Amoebae and Neutrophils by Levchenko, Andre, Iglesias, Pablo A.

“…Eukaryotic cells can detect shallow gradients of chemoattractants with exquisite precision and respond quickly to changes in the gradient steepness and…”
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Disrupting microtubule network immobilizes amoeboid chemotactic receptor in the plasma membrane by de Keijzer, S., Galloway, J., Harms, G.S., Devreotes, P.N., Iglesias, P.A.

“…Signaling cascades are initiated in the plasma membrane via activation of one molecule by another. The interaction depends on the mutual availability of the…”
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Receptor-Mediated and Intrinsic Polarization and Their Interaction in Chemotaxing Cells by Krishnan, J., Iglesias, P.A.

“…Polarization—the clear and persistent localization of different signaling molecules to opposite ends of the cell—is critical for effective chemotaxis in…”
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Chemoattractant signaling in dictyostelium discoideum by Manahan, Carol L, Iglesias, Pablo A, Long, Yu, Devreotes, Peter N

“…Dictyostelium is an accessible organism for studies of signaling via chemoattractant receptors. Chemoattractant-mediated signaling events and components are…”
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State-space solution of the discrete-time minimum entropy control problem via separation by Iglesias, P.A., Mustafa, D.

“…A discrete-time minimum entropy H/sub infinity / control problem is solved. The general solution is obtained by separating the problem into two special cases,…”
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Input-output stability of sampled-data linear time-varying systems by Iglesias, P.A.

“…In this paper we consider the input-output stability of feedback systems consisting of a continuous-time, linear, time-varying plant with a discrete time,…”
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The relationship between minimum entropy control and risk-sensitive control for time-varying systems by Peters, M.A., Iglesias, P.A.

“…The connection between minimum entropy control and risk-sensitive control for linear time-varying systems is investigated. For time-invariant systems, the…”
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Minimum entropy control for discrete-time time-varying systems by Peters, M.A., Iglesias, P.A.

“…Controllers that minimize a closed-loop entropy criterion provide a means of trading off the robustness of H ∞ control with the performance of H 2 optimal…”
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On the poles and zeros of linear, time-varying systems by O'Brien, R.T., Iglesias, P.A.

“…Definition of poles and zeros are presented for continuous-time, linear, time-varying systems. For a linear, time-varying state equation, a set of time-varying…”
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The strictly proper discrete-time controller for the normalized left-coprime factorization robust stabilization problem by Iglesias, P.A.

“…For the discrete-time, normalized left-coprime factorization robust stabilization problem, it is known that a simple formula for the maximum robustness margin…”
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Robustness analysis of biochemical network models by Kim, J, Bates, D G, Postlethwaite, I, Ma, L, Iglesias, P A

“…Biological systems that have been experimentally verified to be robust to significant changes in their environments require mathematical models that are…”
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Robust Controller Design for Linear, Time-Varying Systems by O’Brien, R.T., Iglesias, P.A.

“…This paper examines the design of controllers for linear, time-varying systems. A design procedure is presented that incorporates performance and robustness…”
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Pole/zero cancellations in time-varying systems by O'Brien, Richard T., Iglesias, Pablo A.

“…Poles and zeros are defined for continuous-time, linear, time-varying systems. A pole set for a time-varying state equation defines a stability-preserving…”
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Uncovering directional sensing: where are we headed? by Krishnan, J, Iglesias, P A

“…We survey aspects of directional sensing, i.e. how a cell interprets differences in the external concentration of a chemoattractant to guide its motion, from…”
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Dynamic properties of network motifs contribute to biological network organization by Prill, Robert J, Iglesias, Pablo A, Levchenko, Andre

“…Biological networks, such as those describing gene regulation, signal transduction, and neural synapses, are representations of large-scale dynamic systems…”
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PIP sub(3)-Independent Activation of TorC2 and PKB at the Cell's Leading Edge Mediates Chemotaxis by Kamimura, Y, Xiong, Y, Iglesias, P A, Hoeller, O, Bolourani, P, Devreotes, P N

“…Background: Studies show that high phosphotidylinositol 3,4,5-trisphosphate (PIP sub(3)) promotes cytoskeletal rearrangements and alters cell motility and…”
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