Search Results - "Iglesias, Dario E."

(−)-Epicatechin and the comorbidities of obesity by Cremonini, Eleonora, Iglesias, Dario E., Kang, Jiye, Lombardo, Giovanni E., Mostofinejad, Zahra, Wang, Ziwei, Zhu, Wei, Oteiza, Patricia I.

“…Obesity has major adverse consequences on human health contributing to the development of, among others, insulin resistance and type 2 diabetes, cardiovascular…”
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A randomized placebo-controlled cross-over study on the effects of anthocyanins on inflammatory and metabolic responses to a high-fat meal in healthy subjects by Cremonini, Eleonora, Daveri, Elena, Iglesias, Dario E., Kang, Jiye, Wang, Ziwei, Gray, Russell, Mastaloudis, Angela, Kay, Colin D., Hester, Shelly N., Wood, Steven M., Fraga, Cesar G., Oteiza, Patricia I.

“…This study investigated the effects of supplementation with a cyanidin- and delphinidin-rich extract (CDRE) on the postprandial dysmetabolism, inflammation,…”
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Mitochondrial nitric oxide metabolism during rat heart adaptation to high altitude: effect of sildenafil, L-NAME, and L-arginine treatments by Zaobornyj, Tamara, Valdez, Laura B, Iglesias, Darío E, Gasco, Manuel, Gonzales, Gustavo F, Boveris, Alberto

“…Rats submitted to high altitude (Cerro de Pasco, Perú, 4,340 m, Po(2) = 12.2 kPa) for up to 84 days showed a physiological adaptive response with decreased…”
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Ellagic acid protects Caco-2 cell monolayers against inflammation-induced permeabilization by Iglesias, Dario E., Cremonini, Eleonora, Fraga, Cesar G., Oteiza, Patricia I.

“…Chronic intestinal inflammation involves a cycle of oxidative stress, activation of redox sensitive transcription factors, and barrier permeabilization. The…”
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Curcumin Mitigates TNFα‐Induced Caco‐2 Cell Monolayer Permeabilization Through Modulation of NF‐κB, ERK1/2, and JNK Pathways by Iglesias, Dario E., Cremonini, Eleonora, Oteiza, Patricia I., Fraga, Cesar G.

“…Scope This work studies the capacity of curcumin to inhibit tumor necrosis alpha (TNFα)‐induced inflammation, oxidative stress, and loss of intestinal barrier…”
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Anthocyanins and their metabolites promote white adipose tissue beiging by regulating mitochondria thermogenesis and dynamics by Cremonini, Eleonora, Da Silva, Leane M.E., Lanzi, Cecilia Rodriguez, Marino, Mirko, Iglesias, Dario E., Oteiza, Patricia I.

“…[Display omitted] High-fat diet (HFD) consumption and excess nutrient availability can cause alterations in mitochondrial function and dynamics. We previously…”
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Cyanidin and delphinidin restore colon physiology in high fat diet-fed mice: Involvement of TLR-4 and redox-regulated signaling by Iglesias, Dario E., Cremonini, Eleonora, Hester, Shelly N., Wood, Steven M., Bartlett, Mark, Fraga, Cesar G., Oteiza, Patricia I.

“…Consumption of high fat diets (HFD) mimics a modern or “Western style” diet pattern and can impair intestinal barrier integrity, leading to endotoxemia and…”
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Nitric oxide interacts with mitochondrial complex III producing antimycin-like effects by Iglesias, Darío E., Bombicino, Silvina S., Valdez, Laura B., Boveris, Alberto

“…The effect of NO between cytochromes b and c of the mitochondrial respiratory chain were studied using submitochondrial particles (SMP) from bovine heart and…”
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Hydrogen peroxide, nitric oxide and ATP are molecules involved in cardiac mitochondrial biogenesis in Diabetes by Bombicino, Silvina S., Iglesias, Darío E., Rukavina-Mikusic, Ivana A., Buchholz, Bruno, Gelpi, Ricardo J., Boveris, Alberto, Valdez, Laura B.

“…This study, in an experimental model of type I Diabetes Mellitus in rats, deals with the mitochondrial production rates and steady-state concentrations of H2O2…”
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Supplementation with cyanidin and delphinidin mitigates high fat diet-induced endotoxemia and associated liver inflammation in mice by Cremonini, Eleonora, Iglesias, Dario E, Matsukuma, Karen E, Hester, Shelly N, Wood, Steven M, Bartlett, Mark, Fraga, Cesar G, Oteiza, Patricia I

“…Consumption of high fat diets (HFD) and the associated metabolic endotoxemia can initiate liver inflammation and lipid deposition that with time can progress…”
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(+)-Catechin inhibits heart mitochondrial complex I and nitric oxide synthase: functional consequences on membrane potential and hydrogen peroxide production by Iglesias, Darío E, Bombicino, Silvina S, Boveris, Alberto, Valdez, Laura B

“…In order to study the in vitro effect of flavan-3-ol (+)-catechin on the enzymatic activities of mitochondrial complex I and nitric oxide synthase (mtNOS), as…”
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Mitochondrial nitric oxide production supported by reverse electron transfer by Bombicino, Silvina S., Iglesias, Darío E., Zaobornyj, Tamara, Boveris, Alberto, Valdez, Laura B.

“…Heart phosphorylating electron transfer particles (ETPH) produced NO at 1.2 ± 0.1 nmol NO. min−1 mg protein−1 by the mtNOS catalyzed reaction. These particles…”
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Diabetes impairs heart mitochondrial function without changes in resting cardiac performance by Bombicino, Silvina S., Iglesias, Darío E., Mikusic, Ivana A. Rukavina, D’Annunzio, Verónica, Gelpi, Ricardo J., Boveris, Alberto, Valdez, Laura B.

“…Diabetes is a chronic disease associated to a cardiac contractile dysfunction that is not attributable to underlying coronary artery disease or hypertension,…”
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Complex I syndrome in myocardial stunning and the effect of adenosine by Valdez, Laura B., Zaobornyj, Tamara, Bombicino, Silvina, Iglesias, Darío E., Boveris, Alberto, Donato, Martin, D'Annunzio, Verónica, Buchholz, Bruno, Gelpi, Ricardo J.

“…Isolated rabbit hearts were exposed to ischemia (I; 15 min) and reperfusion (R; 5–30 min) in a model of stunned myocardium. I/R decreased left-ventricle O 2…”
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Heart mitochondrial dysfunction in diabetic rats by Bombicino, S.S., Iglesias, D.E., Rukavina Mikusic, I.A., Boveris, A., Valdez, L.B.

“…Diabetic cardiomyopathy, i.e. the ventricular dysfunction in the absence of hypertension or coronary arterial disease, is a common complication of diabetes…”
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Nitric oxide metabolism in heart mitochondria by ZAOBORNYJ, Tamara, E. IGLESIAS, Dar韔, S. BOMBICINO, Silvina, BOVERIS, Alberto, B. VALDEZ, Laura

“…Normal cardiac function is accomplished through a continuous energy supply provided by mitochondria. Heart mitochondria are the major source of reactive oxygen…”
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Superoxide and hydrogen peroxide productions by NO-inhibited complex III by E. IGLESIAS, Dar韔, S. BOMBICINO, Silvina, BOVERIS, Alberto, B. VALDEZ, Laura

“…Complex III plays a central role in the mitochondrial respiratory chain transferring electrons from ubiquinol to cytochrome c and pumping protons to the…”
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Effects of a cyanidin- and delphinidin-rich extract on mitochondrial dynamics, biogenesis and thermogenesis in adipose tissue of mice fed a high-fat diet by Cremonini, Eleonora, Rodrigue-Lanzi, Cecilia M., Marino, Mirko, Iglesias, Dario E., Fraga, Cesar G., Oteiza, Patricia I.

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Inhibition of mitochondrial complex III by nitric oxide by Valdez, Laura B., Iglesias, Darío E., Bombicino, Silvina S., Boveris, Alberto

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Functional interaction between complex I and mitochondrial NOS (mtNOS) by Bombicino, Silvina S., Iglesias, Darío E., Zaobornyj, Tamara, Boveris, Alberto, Valdez, Laura B.

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