Search Results - "Igisu, Hideki"

Apoptosis induced by acrylamide in SH-SY5Y cells by SUMIZAWA, Tomoyuki, IGISU, Hideki

“…Acrylamide (1-5 mM) dose-dependently decreased cell viability in human neuroblastoma cells (SH-SY5Y). The caspase-3 activity and cell population in sub-G(1)…”
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Release of heat shock proteins from human neuroblastoma cells exposed to acrylamide by Sumizawa, Tomoyuki, Igisu, Hideki

“…When human neuroblastoma cells (SH-SY5Y) were exposed to 0.5 - 5 mM acrylamide for 18 hr, the levels of heat shock proteins (HSPs) of 90, 70 and 27 kDa (Hsp90,…”
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Binding of Human Serum Proteins to Titanium Dioxide Particles In Vitro by Zaqout, Mazen S.K., Sumizawa, Tomoyuki, Igisu, Hideki, Higashi, Toshiaki, Myojo, Toshihiko

“…Objectives： To determine the capacity of human serum proteins to bind to titanium dioxide (TiO2) particles of different polymorphs and sizes. Methods： TiO2…”
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Binding of titanium dioxide nanoparticles to lactate dehydrogenase by Zaqout, Mazen S K, Sumizawa, Tomoyuki, Igisu, Hideki, Wilson, Donald, Myojo, Toshihiko, Ueno, Susumu

“…Measurement of released lactate dehydrogenase (LDH) activity, a commonly used marker of lethal cell injury in both in vitro and in vivo screenings, has been…”
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Involvement of the extracellular signal-regulated protein kinase pathway in phosphorylation of p53 protein and exerting cytotoxicity in human neuroblastoma cells (SH-SY5Y) exposed to acrylamide by OKUNO, Takeo, MATSUOKA, Masato, SUMIZAWA, Tomoyuki, IGISU, Hideki

“…Using human neuroblastoma SH-SY5Y cells, effects of acrylamide on p53 protein and intracellular signal transducting pathways were examined. Acrylamide…”
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Effects of Heavy Metals on Mitogen-Activated Protein Kinase Pathways by MATSUOKA, Masato, IGISU, Hideki

“…The signaling pathways leading to cellular protection or cell death following exposure to heavy metals have not been fully clarified. Mitogen-activated protein…”
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Involvement of the extracellular signal-regulated protein kinase (ERK) pathway in the induction of apoptosis by cadmium chloride in CCRF-CEM cells by Iryo, Yoshihisa, Matsuoka, Masato, Wispriyono, Bambang, Sugiura, Tsutomu, Igisu, Hideki

“…When CCRF-CEM cells were incubated with 5–40 μM CdCl 2, apoptosis was observed most clearly at 10 μM. Prior to the development of apoptosis, mitogen-activated…”
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Phosphorylation of p53 Protein in A549 Human Pulmonary Epithelial Cells Exposed to Asbestos Fibers by Matsuoka, Masato, Igisu, Hideki, Morimoto, Yasuo

“…We examined effects of asbestos exposure on the phosphorylation of p53 protein in human pulmonary epithelial type II cells (A549), which express wild-type p53…”
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Suppression of cadmium-induced JNK/p38 activation and HSP70 family gene expression by LL-Z1640-2 in NIH3T3 cells by Sugisawa, Nobusuke, Matsuoka, Masato, Okuno, Takeo, Igisu, Hideki

“…When NIH3T3 cells were exposed to CdCl 2, the three major mitogen-activated protein kinases (MAPKs), extracellular signal-regulated protein kinase (ERK), c-Jun…”
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Increased cytotoxicity of cadmium in fibroblasts lacking c- fos by Matsuoka, Masato, Wispriyono, Bambang, Igisu, Hideki

“…Cadmium has been known to induce the expression of the c- fos gene in various cell types including fibroblasts. To clarify the biological significance of c-…”
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Activation of Mitogen-Activated Protein Kinases by Tributyltin in CCRF-CEM Cells: Role of Intracellular Ca2 by Yu, Zheng-ping, Matsuoka, Masato, Wispriyono, Bambang, Iryo, Yoshihisa, Igisu, Hideki

“…Effects of tributyltin chloride (TBT) and other organotin compounds on mitogen-activated protein kinases (MAPKs) were examined in CCRF-CEM human T…”
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Protection from cadmium cytotoxicity by N-acetylcysteine in LLC-PK1 cells by Wispriyono, B, Matsuoka, M, Igisu, H, Matsuno, K

“…N-acetylcysteine (NAC) has been known not only to stimulate synthesis of glutathione but also to affect the gene regulation. In our study, effects of NAC on…”
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Acrylamide Encephalopathy by Igisu, Hideki, Matsuoka, Masato

“…Although the toxic effects of acrylamide on the peripheral nervous system have been well established, less attention has been paid to its eftects on the brain…”
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N-methylformamide in urine by Igisu, Hideki, Ezaki, Takafumi

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Methanol by Igisu, Hideki, Koba, Ikuro

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Trichloroacetic acid and trichloroethanol in urine by Igisu, Hideki, Narimatsu, Hayato

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Mandelic acid in urine by Igisu, Hideki, Narimatsu, Hayato

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Hippuric acid and methylhippuric acid in urine by Igisu, Hideki, Ezaki, Takafumi

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Suppression of acrylamide toxicity by carboxyfullerene in human neuroblastoma cells in vitro by Sumizawa, Tomoyuki, Igisu, Hideki

“…In our previous study, we found that caspase-dependent apoptosis played a role in the genesis of toxicity of acrylamide in human neuroblastoma (SH-SY5Y) cells…”
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Neuropsychiatric disorders induced by exposure to metals by Matsuoka, Masato, Igisu, Hideki

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