Search Results - "Igietseme, Joseph"

Rectal administration of a chlamydial subunit vaccine protects against genital infection and upper reproductive tract pathology in mice by Pais, Roshan, Omosun, Yusuf, He, Qing, Blas-Machado, Uriel, Black, Carolyn, Igietseme, Joseph U, Fujihashi, Kohtaro, Eko, Francis O

“…In this study, we tested the hypothesis that rectal immunization with a VCG-based chlamydial vaccine would cross-protect mice against heterologous genital…”
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Role of Epithelial-Mesenchyme Transition in Chlamydia Pathogenesis by Igietseme, Joseph U, Omosun, Yusuf, Stuchlik, Olga, Reed, Matthew S, Partin, James, He, Qing, Joseph, Kahaliah, Ellerson, Debra, Bollweg, Brigid, George, Zenas, Eko, Francis O, Bandea, Claudiu, Liu, Hsi, Yang, Genyan, Shieh, Wun-Ju, Pohl, Jan, Karem, Kevin, Black, Carolyn M

“…Chlamydia trachomatis genital infection in women causes serious adverse reproductive complications, and is a strong co-factor for human papilloma virus…”
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A novel cold-chain free VCG-based subunit vaccine protects against Chlamydia abortus -induced neonatal mortality in a pregnant mouse model by Richardson, Shakyra, Bell, Courtnee R, Medhavi, Fnu, Tanner, Tayhlor, Lundy, Stephanie, Omosun, Yusuf, Igietseme, Joseph U, Eko, Francis O

“…(Cab) causes spontaneous abortion and neonatal mortality in infected ruminants and pregnant women. Most Cab infections are asymptomatic, although they can be…”
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Construction of Recombinant HVT Expressing PmpD, and Immunological Evaluation against Chlamydia psittaci and Marek's Disease Virus by Liu, Shanshan, Sun, Wei, Chu, Jun, Huang, Xiufen, Wu, Zongxue, Yan, Minxin, Zhang, Qiang, Zhao, Peng, Igietseme, Joseph U, Black, Carolyn M, He, Cheng, Li, Yongqing

“…Chlamydia psittaci (C. psittaci) is an obligate intracellular zoonotic pathogen that can be transmitted to humans from birds. No efficacious commercial vaccine…”
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Epidermal Growth Factor Receptor and Transforming Growth Factor β Signaling Pathways Cooperate To Mediate Chlamydia Pathogenesis by Igietseme, Joseph U, Partin, James, George, Zenas, Omosun, Yusuf, Goldstein, Jason, Joseph, Kahaliah, Ellerson, Debra, Eko, Francis O, Pohl, Jan, Bandea, Claudiu, Black, Carolyn M

“…Human genital infection is a major public health concern due to the serious reproductive system complications. binds several receptor tyrosine kinases (RTKs)…”
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Route of Vaccine Administration Influences the Impact of Fms-Like Tyrosine Kinase 3 Ligand (Flt3L) on Chlamydial-Specific Protective Immune Responses by Pais, Roshan, Omosun, Yusuf, Igietseme, Joseph U, Fujihashi, Kohtaro, Eko, Francis O

“…We tested the hypothesis that the impact of the Fms-like tyrosine kinase 3-ligand (Flt3L; FL) on recombinant ghost (rVCG) vaccine-induced chlamydial immunity…”
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Future of human Chlamydia vaccine: potential of self-adjuvanting biodegradable nanoparticles as safe vaccine delivery vehicles by Sahu, Rajnish, Verma, Richa, Dixit, Saurabh, Igietseme, Joseph U, Black, Carolyn M, Duncan, Skyla, Singh, Shree R, Dennis, Vida A

“…There is a persisting global burden and considerable public health challenge by the plethora of ocular, genital and respiratory diseases caused by members of…”
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A unique insight into the MiRNA profile during genital chlamydial infection by Benyeogor, Ifeyinwa, Simoneaux, Tankya, Wu, Yuehao, Lundy, Stephanie, George, Zenas, Ryans, Khamia, McKeithen, Danielle, Pais, Roshan, Ellerson, Debra, Lorenz, W Walter, Omosun, Tolulope, Thompson, Winston, Eko, Francis O, Black, Carolyn M, Blas-Machado, Uriel, Igietseme, Joseph U, He, Qing, Omosun, Yusuf

“…Genital C. trachomatis infection may cause pelvic inflammatory disease (PID) that can lead to tubal factor infertility (TFI). Understanding the pathogenesis of…”
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The Roles of Unfolded Protein Response Pathways in Chlamydia Pathogenesis by George, Zenas, Omosun, Yusuf, Azenabor, Anthony A., Partin, James, Joseph, Kahaliah, Ellerson, Debra, He, Qing, Eko, Francis, Bandea, Claudiu, Svoboda, Pavel, Pohl, Jan, Black, Carolyn M., Igietseme, Joseph U.

“…Chlamydia is an obligate intracellular bacterium that relies on host cells for essential nutrients and adenosine triphosphate (ATP) for a productive infection…”
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Differential miRNA Profiles Correlate With Disparate Immunity Outcomes Associated With Vaccine Immunization and Chlamydial Infection by Howard, Simone, Richardson, Shakyra, Benyeogor, Ifeyinwa, Omosun, Yusuf, Dye, Kamran, Medhavi, Fnu, Lundy, Stephanie, Adebayo, Olayinka, Igietseme, Joseph U, Eko, Francis O

“…Vaccine-induced immune responses following immunization with promising vaccines protected experimental animals from induced upper genital tract pathologies and…”
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Cellular Basis for the Enhanced Efficacy of the Fms-Like Tyrosine Kinase 3 Ligand (FL) Adjuvanted VCG-Based Chlamydia abortus Vaccine by Richardson, Shakyra, Medhavi, Fnu, Tanner, Tayhlor, Lundy, Stephanie, Omosun, Yusuf, Igietseme, Joseph U, Carroll, Darin, Eko, Francis O

“…Efficacious vaccines are needed to control genital chlamydial diseases in humans and the veterinary industry. We previously reported a (Cab) vaccine comprising…”
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Molecular Pathogenesis of Chlamydia Disease Complications: Epithelial-Mesenchymal Transition and Fibrosis by Igietseme, Joseph U, Omosun, Yusuf, Nagy, Tamas, Stuchlik, Olga, Reed, Matthew S, He, Qing, Partin, James, Joseph, Kahaliah, Ellerson, Debra, George, Zenas, Goldstein, Jason, Eko, Francis O, Bandea, Claudiu, Pohl, Jan, Black, Carolyn M

“…The reproductive system complications of genital chlamydial infection include fallopian tube fibrosis and tubal factor infertility. However, the molecular…”
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Effect of Time of Day of Infection on Chlamydia Infectivity and Pathogenesis by Lundy, Stephanie R., Ahmad, Tarek, Simoneaux, Tankya, Benyeogor, Ifeyinwa, Robinson, YeMaya, George, Zenas, Ellerson, Debra, Kirlin, Ward, Omosun, Tolulope, Eko, Francis O., Black, Carolyn M., Blas-Machado, Uriel, DeBruyne, Jason P., Igietseme, Joseph U., He, Qing, Omosun, Yusuf O.

“…Genital chlamydia infection in women causes complications such as pelvic inflammatory disease and tubal factor infertility, but it is unclear why some women…”
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Rare mutations in Pfmdr1 gene of Plasmodium falciparum detected in clinical isolates from patients treated with anti-malarial drug in Nigeria by Idowu, Abel O, Oyibo, Wellington A, Bhattacharyya, Sanjib, Khubbar, Manjeet, Mendie, Udoma E, Bumah, Violet V, Black, Carolyn, Igietseme, Joseph, Azenabor, Anthony A

“…Plasmodium falciparum, the deadliest causative agent of malaria, has high prevalence in Nigeria. Drug resistance causing failure of previously effective drugs…”
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The COVID-19 pandemic in sub-Saharan Africa: The significance of presumed immune sufficiency by Idowu, Abel O., Omosun, Yusuf O., Igietseme, Joseph U., Azenabor, Anthony A.

“…Abstract only…”
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The molecular mechanism of induction of unfolded protein response by Chlamydia by George, Zenas, Omosun, Yusuf, Azenabor, Anthony A., Goldstein, Jason, Partin, James, Joseph, Kahaliah, Ellerson, Debra, He, Qing, Eko, Francis, McDonald, Melissa A., Reed, Matthew, Svoboda, Pavel, Stuchlik, Olga, Pohl, Jan, Lutter, Erika, Bandea, Claudiu, Black, Carolyn M., Igietseme, Joseph U.

“…The unfolded protein response (UPR) contributes to chlamydial pathogenesis, as a source of lipids and ATP during replication, and for establishing the initial…”
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The emerging role of ASC in dendritic cell metabolism during Chlamydia infection by McKeithen, Danielle N, Omosun, Yusuf O, Ryans, Khamia, Mu, Jing, Xie, Zhonglin, Simoneaux, Tankya, Blas-Machado, Uriel, Eko, Francis O, Black, Carolyn M, Igietseme, Joseph U, He, Qing

“…Chlamydia trachomatis is a bacterial agent that causes sexually transmitted infections worldwide. The regulatory functions of dendritic cells (DCs) play a…”
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The immunoregulatory role of alpha enolase in dendritic cell function during Chlamydia infection by Ryans, Khamia, Omosun, Yusuf, McKeithen, Danielle N, Simoneaux, Tankya, Mills, Camilla C, Bowen, Nathan, Eko, Francis O, Black, Carolyn M, Igietseme, Joseph U, He, Qing

“…We have previously reported that interleukin-10 (IL-10) deficient dendritic cells (DCs) are potent antigen presenting cells that induced elevated protective…”
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Author Correction: Shift work influences the outcomes of Chlamydia infection and pathogenesis by Lundy, Stephanie R., Richardson, Shakyra, Ramsey, Anne, Ellerson, Debra, Fengxia, Yan, Onyeabor, Sunny, Kirlin, Ward, Thompson, Winston, Black, Carolyn M., DeBruyne, Jason P., Davidson, Alec J., Immergluck, Lilly C., Blas-Machado, Uriel, Eko, Francis O., Igietseme, Joseph U., He, Qing, Omosun, Yusuf O.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Prevention of Chlamydia-Induced Infertility by Inhibition of Local Caspase Activity by Igietseme, Joseph U., Omosun, Yusuf, Partin, James, Goldstein, Jason, He, Qing, Joseph, Kahaliah, Ellerson, Debra, Ansari, Uzma, Eko, Francis O., Bandea, Claudiu, Zhong, Guangming, Black, Carolyn M.

“…Tubal factor infertility (TFI) represents 36% of female infertility and genital infection by Chlamydia trachomatis (C. trachomatis) is a major cause. Although…”
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