Search Results - "Igase, M"

Creatinine to Cystatin C Ratio as a Marker of Bone Property in Older Adults: The J-Shipp Study by Tabara, Yasuharu, Kohara, K., Okada, Y., Ohyagi, Y., Igase, M.

“…Objectives To clarify whether serum creatinine to cystatin C ratio (CCR), a marker of muscle mass and muscle function may be used as a simple marker of bone…”
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CLINICAL SIGNIFICANCE OF ELEVATED ANKLE-BRACHIAL INDEX DIFFERS DEPENDING ON THE AMOUNT OF APPENDICULAR MUSCLE MASS: THE J-SHIPP AND THE NAGAHAMA STUDY by Tabara, Y, Igase, M, Setoh, K, Ohyagi, Y, Miki, T, Nakayama, T, Kohara, K, Matsuda, F

“…OBJECTIVE:Low ankle-brachial index (ABI) is associated with cardiovascular risk factors. In contrast, the clinical implication of high ABI is less understood,…”
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Bosutinib, an SRC inhibitor, induces caspase‐independent cell death associated with permeabilization of lysosomal membranes in melanoma cells by Noguchi, S., Shibutani, S., Fukushima, K., Mori, T., Igase, M., Mizuno, T.

“…Background SRC kinase (SRC proto‐oncogene, non‐receptor tyrosine kinase) is a promising target for the treatment of solid cancers including human melanoma…”
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Auraptene in the Peels of Citrus Kawachiensis (Kawachibankan) Contributes to the Preservation of Cognitive Function: A Randomized, Placebo-Controlled, Double-Blind Study in Healthy Volunteers by Igase, Michiya, Okada, Y., Ochi, M., Igase, K., Ochi, H., Okuyama, S., Furukawa, Y., Ohyagi, Y.

“…Objectives Dementia, which is characterized by a progressive decline in cognitive function, is a major concern in aging societies. Although a number of…”
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Oncolytic reovirus therapy: Pilot study in dogs with spontaneously occurring tumours by Hwang, C. C., Igase, M., Sakurai, M., Haraguchi, T., Tani, K., Itamoto, K., Shimokawa, T., Nakaichi, M., Nemoto, Y., Noguchi, S., Coffey, M., Okuda, M., Mizuno, T.

“…Oncolytic virotherapy is a novel treatment involving replication‐competent virus in the elimination of cancer. We have previously reported the oncolytic…”
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Skin autofluorescence examination as a diagnostic tool in medical check-ups by Igase, M, Ohara, M, Okada, Y, Ochi, M, Tabara, Y, Kohara, K

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The effects of oncolytic reovirus in canine lymphoma cell lines by Hwang, C. C., Umeki, S., Igase, M., Coffey, M., Noguchi, S., Okuda, M., Mizuno, T.

“…Reovirus is a potent oncolytic virus in many human neoplasms that has reached phase II and III clinical trials. Our laboratory has previously reported the…”
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Facial pigmentation as a biomarker of carotid atherosclerosis in middle-aged to elderly healthy Japanese subjects by Miyawaki, S, Kohara, K, Kido, T, Tabara, Y, Igase, M, Miki, T, Sayama, K

“…Perceived age may be a better predictor of mortality rate than chronological age. We have demonstrated that perceived age was a significant biomarker for…”
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Association of Chr17q25 with cerebral white matter hyperintensities and cognitive impairment: the J-SHIPP study by Tabara, Y., Igase, M., Okada, Y., Nagai, T., Uetani, E., Kido, T., Ochi, N., Takita, R., Yamamoto, M., Kohara, K., Miki, T.

“…Background and purpose A recent genome‐wide association study has successfully identified several genetic variations in the Chr17q25 locus as susceptible…”
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Clinical usefulness of the second peak of radial systolic blood pressure for estimation of aortic systolic blood pressure by Kohara, K, Tabara, Y, Tomita, H, Nagai, T, Igase, M, Miki, T

“…Central aortic blood pressure (BP), obtained from radial arterial waveform using the transfer function method (TFM), has been shown to have prognostic value…”
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Investigation of the cytotoxic effect of flavopiridol in canine lymphoma cell lines by Ema, Y., Igase, M., Takeda, Y., Yanase, T., Umeki, S., Hiraoka, H., Okuda, M., Mizuno, T.

“…The cyclin‐dependent kinase (CDK) inhibitor, flavopiridol, was tested as a potential new cancer therapeutic agent to treat canine lymphoma by examining its…”
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Missense variants of the alanine: glyoxylate aminotransferase 2 gene correlated with carotid atherosclerosis in the Japanese population by Yoshino, Y, Kohara, K, Abe, M, Ochi, S, Mori, Y, Yamashita, K, Igase, M, Tabara, Y, Mori, T, Miki, T, Ueno, S

“…Alanine:glyoxylate aminotransferase 2 (AGXT2; EC 2.6.1.44) degrades asymmetric dimethylarginine (ADMA), a competitive inhibitor of nitric oxide (NO) synthase…”
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Role of GADD153 (growth arrest- and DNA damage-inducible gene 153) in vascular smooth muscle cell apoptosis by Igase, M, Okura, T, Nakamura, M, Takata, Y, Kitami, Y, Hiwada, K

“…GADD153 (growth arrest- and DNA damage-inducible gene 153) is expressed at very low levels in growing cells, but is markedly induced in response to a variety…”
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Effect of reflection of arterial pressure on carotid circulation in essential hypertension by Kohara, Katsuhiko, Jiang, Yinong, Igase, Michiya, Hiwada, Kunio

“…Pressure wave reflection plays a pivotal role in the augmentation of systolic blood pressure. In the present study, the association between reflection of…”
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[PP.06.12] B-TYPE NATRIURETIC PEPTIDE IS A DETERMINANT OF THE NOCTURNAL INCREASE IN BLOOD PRESSURE INDEPENDENTLY OF ARTERIAL HYPERTROPHY AND HYPOXIA by Tabara, Y., Igase, M., Miki, T., Ohyagi, Y., Matsuda, F., Kohara, K.

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Glucose intolerance associating with cognitive impairment and brain diabetes as a therapeutic target in alzheimer’s disease by Ohyagi, Y., Ohara, M., Igase, M., Nakamura, N., Imamura, T., Yanagihara, Y., Kira, J., Watanabe, A., Fujii, N.

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B005: Association between low wall shear stress and plasma VCAM-1 in subjects with risk factors for atherosclerosis by Jiang, Y.N., Kohara, K., Igase, M., Okura, T., Kitami, Y., Hiwada, K.

“…In vitro studies demonstrated adhesion molecules could connect low shear stress and atherosclerosis. In the present study, we investigated the relationship…”
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A case of myasthenia gravis with an invasive thymoma infiltrating the superior vena cava and right atrium and causing lung metastasis by Ochi, Masayuki, Toi, Takayuki, Kamogawa, Kenji, Nagai, Tokihisa, Taguchi, Keiko, Kawano, Yuji, Igase, Michiya, Kohara, Katsuhiko, Miki, Tetsuro

“…A 72-year-old woman was admitted to a local hospital with general fatigue, ptosis and dysarthria. Her anti-AchR antibody titer was high, so myasthenia gravis…”
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A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2 by Wu, Ying, Gao, He, Li, Huaixing, Tabara, Yasuharu, Nakatochi, Masahiro, Chiu, Yen-Feng, Park, Eun Jung, Wen, Wanqing, Adair, Linda S, Borja, Judith B, Cai, Qiuyin, Chang, Yi-Cheng, Chen, Peng, Croteau-Chonka, Damien C, Fogarty, Marie P, Gan, Wei, He, Chih-Tsueng, Hsiung, Chao A, Hwu, Chii-Min, Ichihara, Sahoko, Igase, Michiya, Jo, Jaeseong, Kato, Norihiro, Kawamoto, Ryuichi, Kuzawa, Christophor W, Lee, Jeannette J M, Liu, Jianjun, Lu, Ling, McDade, Thomas W, Osawa, Haruhiko, Sheu, Wayne H-H, Teo, Yvonne, Vadlamudi, Swarooparani, Van Dam, Rob M, Wang, Yiqin, Xiang, Yong-Bing, Yamamoto, Ken, Ye, Xingwang, Young, Terri L, Zheng, Wei, Zhu, Jingwen, Shu, Xiao-Ou, Shin, Chol, Jee, Sun Ha, Chuang, Lee-Ming, Miki, Tetsuro, Yokota, Mitsuhiro, Lin, Xu, Mohlke, Karen L, Tai, E Shyong

“…Blood levels of adiponectin, an adipocyte-secreted protein correlated with metabolic and cardiovascular risks, are highly heritable. Genome-wide association…”
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Cardiac autonomic dysfunction in patients with progressive supranuclear palsy and corticobasal degeneration by Ochi, M., Ochi, H., Senzaki, K., Ishikawa, H., Shiraoka, A., Matsumoto, S., Katoh, T., Okada, Y., Ohara, M., Igase, M., Ohyagi, Y.

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