Search Results - "Igarashi, Rumi"

Functional roles of graft-infiltrating lymphocytes during early-phase post-transplantation in mouse cardiac transplantation models by Ganchiku, Yoshikazu, Goto, Ryoichi, Kanazawa, Ryo, Ota, Takuji, Shibuya, Kazuaki, Fukasaku, Yasutomo, Kobayashi, Nozomi, Igarashi, Rumi, Kawamura, Norio, Zaitsu, Masaaki, Watanabe, Masaaki, Taketomi, Akinobu

“…Immunological behavior of graft-infiltrating lymphocytes (GILs) determines the graft fate (i.e., rejection or acceptance). Nevertheless, the functional…”
Get more information

Immunosuppressive effects of DTCM-G, a novel inhibitor of the mTOR downstream signaling pathway by Shibasaki, Susumu, Yamashita, Kenichiro, Goto, Ryoichi, Wakayama, Kenji, Tsunetoshi, Yusuke, Zaitsu, Masaaki, Igarashi, Rumi, Haga, Sanae, Ozaki, Michitaka, Umezawa, Kazuo, Todo, Satoru

“…A newly developed compound, 3-[(dodecylthiocarbonyl)methyl]-glutarimide (DTCM-G), has been shown to inhibit nuclear translocation of c-Fos/c-Jun in a murine…”
Get full text

Triazolopyrimidine derivative NK026680 and donor-specific transfusion induces CD4+CD25+Foxp3+ T cells and ameliorates allograft rejection in an antigen-specific manner by Emoto, Shin, Shibasaki, Susumu, Nagatsu, Akihisa, Goto, Ryoichi, Ono, Hitoshi, Fukasaku, Yasutomo, Igarashi, Rumi, Ota, Takuji, Fukai, Moto, Shimamura, Tsuyoshi, Saiga, Kan, Taketomi, Akinobu, Murakami, Masaaki, Todo, Satoru, Yamashita, Kenichiro

“…We have previously demonstrated the unique properties of a new triazolopyrimidine derivative, NK026680, which exerts immunosuppressive effects in rat heart…”
Get full text

3-[(Dodecylthiocarbonyl)Methyl]-Glutarimide Attenuates Graft Arterial Disease by Suppressing Alloimmune Responses and Vascular Smooth Muscle Cell Proliferation by Zaitsu, Masaaki, Yamashita, Kenichiro, Shibasaki, Susumu, Tsunetoshi, Yusuke, Fukai, Moto, Ogura, Masaomi, Yoshida, Tadashi, Igarashi, Rumi, Kobayashi, Nozomi, Umezawa, Kazuo, Todo, Satoru

“…BACKGROUNDGraft arterial disease (GAD) is a major cause of late graft loss after organ transplantation. Alloimmune responses and vascular remodeling eventually…”
Get full text

Dendritic Cells Conditioned With NK026680 Prolong Cardiac Allograft Survival in Mice by SHIBASAKI, Susumu, YAMASHITA, Kenichiro, OZAKI, Michitaka, TODO, Satoru, YANAGAWA, Yoshiki, GOTO, Ryoichi, WAKAYAMA, Kenji, HIROKATA, Gentaro, TSUNETOSHI, Yusuke, ZAITSU, Masaaki, IGARASHI, Rumi, HAGA, Sanae

“…Pharmacologically modulated dendritic cells (DCs) can potentially regulate alloimmune responses. We examined the characteristics of immunoregulatory DCs…”
Get full text

Immunomodulatory Effect of Nuclear Factor-κB Inhibition by Dehydroxymethylepoxyquinomicin in Combination With Donor-Specific Blood Transfusion by GOTO, Ryoichi, YAMASHITA, Kenichiro, HIROKATA, Gentaro, SHIBATA, Tomohiro, ZAITSU, Masaaki, UMEZAWA, Kazuo, OZAKI, Michitaka, TODO, Satoru, AOYAGI, Takeshi, UEKI, Shinya, UNO, Motohiro, OURA, Tetsu, KOBAYASHI, Nozomi, IGARASHI, Rumi, SHIBASAKI, Susumu, WAKAYAMA, Kenji

“…Nuclear factor-κB (NF-κB) is a key molecule in alloimmune responses, however, its role in tolerance induction is not clear. We have previously reported that…”
Get full text

NK026680 inhibits T-cell function in an IL-2-dependent manner and prolongs cardiac allograft survival in rats by Shibasaki, Susumu, Yamashita, Kenichiro, Goto, Ryoichi, Oura, Tetsu, Wakayama, Kenji, Hirokata, Gentaro, Shibata, Tomohiro, Igarashi, Rumi, Haga, Sanae, Ozaki, Michitaka, Todo, Satoru

“…Abstract NK026680 is a triazolopyrimidine derivative that has been shown to inhibit dendritic cell maturation and activation. Here, we examined the…”
Get full text

Compensatory recovery of liver mass by Akt-mediated hepatocellular hypertrophy in liver-specific STAT3-deficient mice by Haga, Sanae, Ogawa, Wataru, Inoue, Hiroshi, Terui, Keita, Ogino, Tetsuya, Igarashi, Rumi, Takeda, Kiyoshi, Akira, Shizuo, Enosawa, Shin, Furukawa, Hiroyuki, Todo, Satoru, Ozaki, Michitaka

“…Liver regeneration following hepatectomy is complicated and involves a variety of interacting factors. The present study was designed to study the roles of…”
Get full text