Search Results - "Iftikhar, Fizza"

Cinchona alkaloids as natural fetal hemoglobin inducing agents in human erythroleukemia cells by Iftikhar, Fizza, Ali, Hamad, Musharraf, Syed Ghulam

“…Pharmacologically mediated reactivation of γ-globin gene with an increase in fetal hemoglobin production, is a cost effective experimental therapeutic…”
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Lyophilization Based Isolation of Exosomes by Qazi, Rida E Maria, Sajid, Zahra, Zhao, Chunqiu, Hussain, Irfan, Iftikhar, Fizza, Jameel, Muhammad, Rehman, Fawad Ur, Mian, Afsar Ali

“…Exosomes are nanoscale extracellular vesicles which regulate intercellular communication. They have great potential for application in nanomedicine. However,…”
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In Vitro and In Vivo Studies for the Investigation of γ-Globin Gene Induction by Adhatoda vasica : A Pre-Clinical Study of HbF Inducers for β-Thalassemia by Iftikhar, Fizza, Rahman, Saeedur, Khan, Muhammad Behroz Naeem, Khan, Kanwal, Khan, Muhammad Noman, Uddin, Reaz, Musharraf, Syed Ghulam

“…Fetal hemoglobin (HbF) is a potent genetic modifier, and the γ-globin gene induction has proven to be a sustainable therapeutic approach for the management of…”
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P1460: INDUCTION OF FETAL HEMOGLOBIN BY TARGETED DELETION OF ZINC FINGER DOMAIN WITHIN BCL11A GENE USING CRISPR‐CAS9 TECHNOLOGY by Hussain, Irfan, Mumtaz, Kainaat, Iftikhar, Fizza, Farooq, Safana, Muhammad, Syed, Ahmed, Areeb, Khan, Dilawar, Hassan, Hammad, Ottmann, Oliver, Mian, Afsar

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Evaluation of the chronic intoxication of fluoride on human serum metabolome using untargeted metabolomics by Usman, Muhammad, Ali, Arslan, Jabbar Siddiqui, Amna, Iftikhar, Fizza, Kumari, Sindhia, Sibt-e-Hassan, Syed, Shad, Raja, Rafique, Tahir, Kashif Raza, Syed, El-Seedi, Hesham R., Uddin, Jalal, Musharraf, Syed Ghulam

“…Drinking water is the main source of fluoride intake for the human body and its regulated consumption helps in decreasing dental caries. However, excessive…”
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Monoterpenes as therapeutic candidates to induce fetal hemoglobin synthesis and up-regulation of gamma-globin gene: An in vitro and in vivo investigation by Iftikhar, Fizza, Khan, Muhammad Behroz Naeem, Musharraf, Syed Ghulam

“…Pharmacologically induced production of fetal hemoglobin (HbF) is a pragmatic therapeutic strategy for the reduction of globin chain imbalance and improving…”
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BCL11A-targeted γ-globin gene induction by triterpenoid glycosides of Fagonia indica: A preclinical scientific validation of indigenous herb for the treatment of β-hemoglobinopathies by Iftikhar, Fizza, Khan, Muhammad Behroz Naeem, Tehreem, Syeda, Kanwal, Nayab, Musharraf, Syed Ghulam

“…[Display omitted] •Fagonia indica and its isolated compounds have shown prominent erythroid differentiation ability.•Comp. 8 was identified as a promising…”
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Acidotic and hypoxic tumor microenvironment induces changes to histone acetylation and methylation in oral squamous cell carcinoma by Khan, Tajwali, Iftikhar, Fizza, Akhlaq, Rafia, Musharraf, Syed Ghulam, Ali, Arslan

“…Hypoxia and acidosis are ubiquitous hallmarks of the tumor microenvironment (TME), and in most solid cancers they have been linked to rewired cancer cell…”
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XMN polymorphism along with HU administration renders alterations to RBC membrane lipidome in β-thalassemia patients by Khan, Muhammad Behroz Naeem, Iftikhar, Fizza, Ali, Muhammad, Danish, Asma, Shamsi, Tahir, Musharraf, Syed Ghulam, Siddiqui, Amna Jabbar

“…RBCs membrane loses its integrity during hemoglobinopathies such as β-thalassemia and sickle cell disease. The severity of β-thalassemia has been historically…”
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Thiourea derivatives induce fetal hemoglobin production in-vitro: A new class of potential therapeutic agents for β-thalassemia by Ali, Hamad, Iftikhar, Fizza, Shafi, Sarah, Siddiqui, Hina, Khan, Ishtiaq Ahmad, Choudhary, M.Iqbal, Musharraf, Syed Ghulam

“…Fetal hemoglobin (HbF) induction is a cost-effective therapeutic approach for the treatment of β-hemoglobinopathies like β-thalassemia and sickle cell anemia…”
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Abstract 4040: Asciminib activates erythroid differentiation in K562 cell line by Hassan, Hammad, Yousuf, Sarah, Ahmed, Syed Muhammad, Ruknuddin, Karim, Raees, Hadiqa, Habib, Sadia, Iftikhar, Fizza, Mian, Afsar Ali, Lalani, Elnasir

“…Abstract Background: Asciminib an allosteric tyrosine kinase inhibitor (TKI) was recently approved by the FDA for managing Philadelphia positive chronic…”
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