Search Results - "Ifrim, Daniela C."
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Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes
Published in Cell host & microbe (16-08-2012)“…Immunological memory in vertebrates is often exclusively attributed to T and B cell function. Recently it was proposed that the enhanced and sustained innate…”
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Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes
Published in Proceedings of the National Academy of Sciences - PNAS (23-10-2012)“…Adaptive features of innate immunity, recently described as “trained immunity,” have been documented in plants, invertebrate animals, and mice, but not yet in…”
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Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors
Published in Clinical and vaccine immunology (01-04-2014)“…Upon priming with Candida albicans or with the fungal cell wall component β-glucan, monocytes respond with an increased cytokine production upon restimulation,…”
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Role of Dectin-2 for Host Defense against Systemic Infection with Candida glabrata
Published in Infection and Immunity (01-03-2014)“…OA Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis
Published in Journal of interferon & cytokine research (01-04-2016)“…Despite the fact that Candida albicans is an important human fungal pathogen and Dectin-2 is a major pattern recognition receptor for fungi, our knowledge…”
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Candida albicans primes TLR cytokine responses through a Dectin-1/Raf-1-mediated pathway
Published in The Journal of immunology (1950) (15-04-2013)“…The immune system is essential to maintain homeostasis with resident microbial populations, ensuring that the symbiotic host-microbial relationship is…”
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mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
Published in Science (American Association for the Advancement of Science) (26-09-2014)“…Epigenetic reprogramming of myeloid cells, also known as trained immunity, confers nonspecific protection from secondary infections. Using histone modification…”
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Fungal Chitin Induces Trained Immunity in Human Monocytes during Cross-talk of the Host with Saccharomyces cerevisiae
Published in The Journal of biological chemistry (08-04-2016)“…The immune system is essential to maintain the mutualistic homeostatic interaction between the host and its micro- and mycobiota. Living as a commensal,…”
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Antifungal innate immunity: recognition and inflammatory networks
Published in Seminars in immunopathology (01-03-2015)“…A large variety of fungi are present in the environment, among which a proportion colonizes the human body, usually without causing any harm. However,…”
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mTOR/HIF1α-mediated aerobic glycolysis as metabolic basis for trained immunity
Published in Science (American Association for the Advancement of Science) (26-09-2014)“…Epigenetic reprogramming of myeloid cells by infection or vaccination, termed trained immunity, confers non-specific protection from secondary infections. We…”
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mTOR- and HIF-1[alpha]-mediated aerobic glycolysis as metabolic basis for trained immunity
Published in Science (American Association for the Advancement of Science) (26-09-2014)“…Introduction Trained immunity refers to the memory characteristics of the innate immune system. Memory traits of innate immunity have been reported in plants…”
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