Search Results - "Ienne, Susan"
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Whole-exome sequencing reveals the impact of UVA light mutagenesis in xeroderma pigmentosum variant human cells
Published in Nucleic acids research (28-02-2020)“…UVA-induced mutagenesis was investigated in human pol eta-deficient (XP-V) cells through whole-exome sequencing. In UVA-irradiated cells, the increase in the…”
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A novel ABCG-like transporter of Trypanosoma cruzi is involved in natural resistance to benznidazole
Published in Memórias do Instituto Oswaldo Cruz (01-05-2015)“…Benznidazole (BZ) is one of the two drugs used for Chagas disease treatment. Nevertheless therapeutic failures of BZ have been reported, which were mostly…”
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Alteration of hippocampal Egr3, GABA A receptors, Il-1β, Il6 and Ccl3 expression in audiogenic tremor mice after seizure
Published in Epilepsy & behavior (01-12-2022)“…•Hippocampal proinflammatory cytokines and GABA A receptors were altered after a seizure.•Overexpression of Ccl3 mRNA was observed in the hippocampus of naive…”
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ABCG-like transporter of Trypanosoma cruzi involved in benznidazole resistance: Gene polymorphisms disclose inter-strain intragenic recombination in hybrid isolates
Published in Infection, genetics and evolution (01-04-2015)“…•The sequence of the ATP-binding cassette transporter TcABCG1 gene of fourteen T. cruzi strains was determined.•Gene polymorphisms were not associated with…”
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Chemogenomic study of gemcitabine using Saccharomyces cerevisiae as model cell—molecular insights about chemoresistance
Published in Brazilian journal of microbiology (01-06-2020)“…Gemcitabine (GEM) is the drug used as first line to treat pancreatic cancer, one of the most devastating human tumors. This peculiar type of tumor develops…”
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Behavioral and neurochemical characterization of the spontaneous mutation tremor, a new mouse model of audiogenic seizures
Published in Epilepsy & behavior (01-04-2020)“…The tremor mutant phenotype results from an autosomal recessive spontaneous mutation arisen in a Swiss–Webster mouse colony. The mutant mice displayed normal…”
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Draft genome sequences of two fluoroquinolone-resistant CTX-M-15-producing Escherichia coli ST90 (ST23 complex) isolated from a calf and a dairy cow in South America
Published in Journal of global antimicrobial resistance. (01-12-2017)“…Farm animals have been recognised as important carriers and reservoirs of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli. The aim of this…”
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Auxin production by the plant trypanosomatid Phytomonas serpens and auxin homoeostasis in infected tomato fruits
Published in Parasitology (01-09-2014)“…Previously we have characterized the complete gene encoding a pyruvate decarboxylase (PDC)/indolepyruvate decarboxylase (IPDC) of Phytomonas serpens, a…”
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Draft genome sequences of KPC-2- and CTX-M-15-producing Klebsiella pneumoniae ST437 isolated from a clinical sample and urban rivers in Sao Paulo, Brazil
Published in Journal of global antimicrobial resistance. (01-03-2019)“…KPC-producing Klebsiella pneumoniae is considered one of the most worrisome multidrug-resistant micro-organisms in nosocomial infections. It has also been…”
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Draft genome sequence of an environmental multidrug-resistant Klebsiella pneumoniae ST340/CC258 harbouring blaCTX-M-15 and blaKPC-2 genes
Published in Journal of global antimicrobial resistance. (01-03-2017)“…Anthropogenic activities, including the release of wastewater and sewage from hospitals, have contributed to the contamination of aquatic environments, raising…”
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Draft genome sequence of a multidrug-resistant Aeromonas hydrophila ST508 strain carrying rmtD and blaCTX-M-131 isolated from a bloodstream infection
Published in Journal of global antimicrobial resistance. (01-09-2017)“…Here we report the draft genome sequence of a multidrug-resistant (MDR) Aeromonas hydrophila strain belonging to sequence type 508 (ST508) isolated from a…”
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Draft genome sequence of a multidrug-resistant Aeromonas hydrophila ST508 strain carrying rmtD and bla CTX-M-131 isolated from a bloodstream infection
Published in Journal of global antimicrobial resistance. (01-09-2017)“…Here we report the draft genome sequence of a multidrug-resistant (MDR) Aeromonas hydrophila strain belonging to sequence type 508 (ST508) isolated from a…”
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Draft genome sequence of a CTX-M-15-producing Klebsiella pneumoniae sequence type 340 (clonal complex 258) isolate from a food-producing animal
Published in Journal of global antimicrobial resistance. (01-12-2016)“…Klebsiella pneumoniae carrying blaCTX-M-15 have been widely disseminated in hospital settings. In this regard, most clinically important strains belong to…”
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Horizontal gene transfer confers fermentative metabolism in the respiratory-deficient plant trypanosomatid Phytomonas serpens
Published in Infection, genetics and evolution (01-04-2012)“…► Characterisation of the gene for a pyruvate/indolepyruvate decarboxylase (PDC/IPDC) of P. serpens. ► Conservation of PDC/IPDC gene sequence in 14 Phytomonas…”
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Genomic organization and transcription analysis of the 195-bp satellite DNA in Trypanosoma cruzi
Published in Molecular and biochemical parasitology (01-07-2008)“…The 195-bp satellite DNA is the most abundant Trypanosoma cruzi repetitive sequence. Here we show by RNA blotting and RT-PCR that 195 SAT is intensely…”
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Draft genome sequence of an environmental multidrug-resistant Klebsiella pneumoniae ST340/CC258 harbouring bla CTX-M-15 and bla KPC-2 genes
Published in Journal of global antimicrobial resistance. (01-03-2017)“…Anthropogenic activities, including the release of wastewater and sewage from hospitals, have contributed to the contamination of aquatic environments, raising…”
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Draft genome sequence of a multidrug-resistant KPC-2-producing Enterobacter aerogenes isolated from a hospitalised patient in Brazil
Published in Journal of global antimicrobial resistance. (01-09-2017)“…Multidrug-resistant (MDR) Enterobacter aerogenes strains are frequently associated with nosocomial infections and high mortality rates, representing a serious…”
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