Search Results - "Idikuda, Vinay"
-
1
Activation of the archaeal ion channel MthK is exquisitely regulated by temperature
Published in eLife (04-12-2020)“…Physiological response to thermal stimuli in mammals is mediated by a structurally diverse class of ion channels, many of which exhibit polymodal behavior. To…”
Get full text
Journal Article -
2
cAMP binding to closed pacemaker ion channels is non-cooperative
Published in Nature (London) (22-07-2021)“…Electrical activity in the brain and heart depends on rhythmic generation of action potentials by pacemaker ion channels (HCN) whose activity is regulated by…”
Get full text
Journal Article -
3
Preparation of Giant Escherichia coli spheroplasts for Electrophysiological Recordings
Published in Bio-protocol (20-12-2021)“…Prokaryotic ion channels have been instrumental in furthering our understanding of many fundamental aspects of ion channels' structure and function. However,…”
Get full text
Journal Article -
4
Membrane phospholipids induce moderate positive cooperativity in closed pacemaker channels
Published in Biophysical journal (10-02-2023)Get full text
Journal Article -
5
cAMP binds to closed, inactivated, and open sea urchin HCN channels in a state-dependent manner
Published in The Journal of general physiology (04-02-2019)“…Hyperpolarization-activated cyclic-nucleotide-modulated (HCN) channels are nonselective cation channels that regulate electrical activity in the heart and…”
Get full text
Journal Article -
6
Shank3‐deficient thalamocortical neurons show HCN channelopathy and alterations in intrinsic electrical properties
Published in The Journal of physiology (01-04-2018)“…Key points Shank3 increases the HCN channel surface expression in heterologous expression systems. Shank3Δ13–16 deficiency causes significant reduction in HCN2…”
Get full text
Journal Article -
7
Singlet oxygen modification abolishes voltage-dependent inactivation of the sea urchin spHCN channel
Published in The Journal of general physiology (03-09-2018)“…Photochemically or metabolically generated singlet oxygen ( O ) reacts broadly with macromolecules in the cell. Because of its short lifetime and working…”
Get full text
Journal Article -
8
Photodynamic Modification of Sea Urchin spHCN Channel
Published in Biophysical journal (27-01-2015)Get full text
Journal Article