Search Results - "Ideno, Noboru"

A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination by Ideno, Noboru, Yamaguchi, Hiroshi, Okumura, Takashi, Huang, Jonathon, Brun, Mitchell J., Ho, Michelle L., Suh, Junghae, Gupta, Sonal, Maitra, Anirban, Ghosh, Bidyut

“…Genetically engineered mouse models (GEMMs) that recapitulate the major genetic drivers in pancreatic ductal adenocarcinoma (PDAC) have provided unprecedented…”
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Congenital biliary dilatation in the era of laparoscopic surgery, focusing on the high incidence of anatomical variations of the right hepatic artery by Mori, Yasuhisa, Nakata, Kohei, Aly, Mohammed Y. F., Ideno, Noboru, Ikenaga, Naoki, Okabe, Yasuhiro, Ishigami, Kousei, Oda, Yoshinao, Nakamura, Masafumi

“…Background The present study aimed to evaluate anatomical variations of the right hepatic artery (RHA) in patients with congenital biliary dilatation (CBD) and…”
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Early Detection of Pancreatic Cancer: Role of Biomarkers in Pancreatic Fluid Samples by Ideno, Noboru, Mori, Yasuhisa, Nakamura, Masafumi, Ohtsuka, Takao

“…Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths worldwide. Most patients with PDAC present with symptomatic,…”
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Peroral pancreatoscopy using the SpyGlass system for the assessment of intraductal papillary mucinous neoplasm of the pancreas by Nagayoshi, Yosuke, Aso, Teppei, Ohtsuka, Takao, Kono, Hiroshi, Ideno, Noboru, Igarashi, Hisato, Takahata, Shunichi, Oda, Yoshinao, Ito, Tetsuhide, Tanaka, Masao

“…Background Peroral pancreatoscopy (POPS) using a mother–baby endoscope system is often useful for assessment of intraductal papillary mucinous neoplasm (IPMN)…”
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Subtypes in pancreatic ductal adenocarcinoma based on niche factor dependency show distinct drug treatment responses by Shinkawa, Tomohiko, Ohuchida, Kenoki, Mochida, Yuki, Sakihama, Kukiko, Iwamoto, Chika, Abe, Toshiya, Ideno, Noboru, Mizuuchi, Yusuke, Shindo, Koji, Ikenaga, Naoki, Moriyama, Taiki, Nakata, Kohei, Oda, Yoshinao, Nakamura, Masafumi

“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by abundant stroma in which microenvironmental (niche) factors promote PDAC progression. In mouse…”
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Involvement of angiogenesis in cancer-associated acinar-to-ductal metaplasia lesion of pancreatic cancer invasive front by Fei, Shuang, Ohuchida, Kenoki, Kibe, Shin, Yan, Zilong, Iwamoto, Chika, Shinkawa, Tomohiko, Zhang, Bo, Kawata, Jun, Abe, Toshiya, Ideno, Noboru, Ikenaga, Naoki, Nakata, Kohei, Oda, Yoshinao, Nakamura, Masafumi

“…Purpose This study aimed to demonstrate the involvement of angiogenesis in cancer-associated acinar-to-ductal metaplasia (CA-ADM) lesion of invasive front…”
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Long-Term Outcomes After Total Pancreatectomy: Special Reference to Survivors’ Living Conditions and Quality of Life by Watanabe, Yusuke, Ohtsuka, Takao, Matsunaga, Taketo, Kimura, Hideyo, Tamura, Koji, Ideno, Noboru, Aso, Teppei, Miyasaka, Yoshihiro, Ueda, Junji, Takahata, Shunichi, Igarashi, Hisato, Inoguchi, Toyoshi, Ito, Tetsuhide, Tanaka, Masao

“…Background Although recent studies have confirmed the safety of total pancreatectomy (TP), appropriate selection of patients for TP has not been well…”
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Tumor-associated neutrophils upregulate Nectin2 expression, creating the immunosuppressive microenvironment in pancreatic ductal adenocarcinoma by Luo, Haizhen, Ikenaga, Naoki, Nakata, Kohei, Higashijima, Nobuhiro, Zhong, Pingshan, Kubo, Akihiro, Wu, Chenyi, Tsutsumi, Chikanori, Shimada, Yuki, Hayashi, Masataka, Oyama, Koki, Date, Satomi, Abe, Toshiya, Ideno, Noboru, Iwamoto, Chika, Shindo, Koji, Ohuchida, Kenoki, Oda, Yoshinao, Nakamura, Masafumi

“…Tumor-associated neutrophils (TANs) constitute an abundant component among tumor-infiltrating immune cells and have recently emerged as a critical player in…”
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Clinical significance of postpancreatectomy acute pancreatitis defined by the International Study Group for Pancreatic Surgery by Ikenaga, Naoki, Nakata, Kohei, Fujita, Nobuhiro, Abe, Toshiya, Ideno, Noboru, Ishigami, Kousei, Nakamura, Masafumi

“…Aim The International Study Group for Pancreatic Surgery (ISGPS) developed a structured definition of postpancreatectomy acute pancreatitis (PPAP) in 2021…”
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S100P in Duodenal Fluid Is a Useful Diagnostic Marker for Pancreatic Ductal Adenocarcinoma by Matsunaga, Taketo, Ohtsuka, Takao, Asano, Koichi, Kimura, Hideyo, Ohuchida, Kenoki, Kitada, Hidehisa, Ideno, Noboru, Mori, Yasuhisa, Tokunaga, Shoji, Oda, Yoshinao, Guha, Sushovan, Raimondo, Massimo, Nakamura, Masafumi, Tanaka, Masao

“…The development of an effective screening method for pancreatic ductal adenocarcinoma (PDAC) is of paramount importance. This study assessed the diagnostic…”
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Assessment of clonality of multisegmental main duct intraductal papillary mucinous neoplasms of the pancreas based on GNAS mutation analysis by Tamura, Koji, MD, Ohtsuka, Takao, MD, PhD, Matsunaga, Taketo, MD, Kimura, Hideyo, MD, Watanabe, Yusuke, MD, Ideno, Noboru, MD, PhD, Aso, Teppei, MD, PhD, Miyazaki, Tetsuyuki, MD, Ohuchida, Kenoki, MD, PhD, Takahata, Shunichi, MD, PhD, Ito, Tetsuhide, MD, PhD, Ushijima, Yasuhiro, MD, PhD, Oda, Yoshinao, MD, PhD, Mizumoto, Kazuhiro, MD, PhD, Tanaka, Masao, MD, PhD, FACS

“…Background Main duct intraductal papillary mucinous neoplasms (MD-IPMNs) may occur in 1 or multiple segments of the pancreatic duct. Unlike multifocal branch…”
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Braun enteroenterostomy reduces delayed gastric emptying after pylorus-preserving pancreatoduodenectomy: a retrospective review by Watanabe, Yusuke, M.D, Ohtsuka, Takao, M.D., Ph.D, Kimura, Hideyo, M.D, Matsunaga, Taketo, M.D, Tamura, Koji, M.D, Ideno, Noboru, M.D, Aso, Teppei, M.D, Miyasaka, Yoshihiro, M.D., Ph.D, Ueda, Junji, M.D., Ph.D, Takahata, Shunichi, M.D., Ph.D, Tanaka, Masao, M.D., Ph.D., F.A.C.S

“…Abstract Background Several recent studies have suggested that Braun enteroenterostomy (BEE) during conventional pancreatoduodenectomy might decrease delayed…”
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Profiling of Autoantibodies in Sera of Pancreatic Cancer Patients by Nagayoshi, Yosuke, Nakamura, Masafumi, Matsuoka, Kazuhiro, Ohtsuka, Takao, Mori, Yasuhisa, Kono, Hiroshi, Aso, Teppei, Ideno, Noboru, Takahata, Shunichi, Ryo, Akihide, Takeda, Hiroyuki, Ito, Tetsuhide, Oda, Yoshinao, Endo, Yaeta, Sawasaki, Tatsuya, Tanaka, Masao

“…Background Although autoantibodies to cancer antigens are candidates for biomarkers, no comprehensive studies to detect cancer-specific antibodies have been…”
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Role of Pancreatic Juice Cytology in the Preoperative Management of Intraductal Papillary Mucinous Neoplasm of the Pancreas in the Era of International Consensus Guidelines 2012 by Ohtsuka, Takao, Matsunaga, Taketo, Kimura, Hideyo, Watanabe, Yusuke, Tamura, Koji, Ideno, Noboru, Aso, Teppei, Miyasaka, Yoshihiro, Ueda, Junji, Takahata, Shunichi, Osoegawa, Takashi, Igarashi, Hisato, Ito, Tetsuhide, Ushijima, Yasuhiro, Ookubo, Fumihiko, Oda, Yoshinao, Mizumoto, Kazuhiro, Tanaka, Masao

“…Background Routine endoscopic retrograde pancreatography (ERP) for pancreatic juice cytology (PJC) during management of intraductal papillary mucinous neoplasm…”
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MicroRNA‐20a in extracellular vesicles derived from duodenal fluid is a possible biomarker for pancreatic ductal adenocarcinoma by Taniguchi, Takashi, Ideno, Noboru, Araki, Tomoyuki, Miura, Shun, Yamamoto, Masahiro, Nakafusa, Tomoki, Higashijima, Nobuhiro, Yamamoto, Takeo, Tamura, Koji, Nakamura, So, Abe, Toshiya, Ikenaga, Naoki, Nakata, Kohei, Ohuchida, Kenoki, Oda, Yoshinao, Ohtsuka, Takao, Nakamura, Masafumi

“…Background Pancreatic ductal adenocarcinoma (PDAC) has a high mortality rate owing to its late diagnosis and aggression. In addition, there are relatively few…”
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Predictive factors of operability after neoadjuvant chemotherapy in resectable or borderline resectable pancreatic cancer: a single-center retrospective study by Murakami, Masatoshi, Fujimori, Nao, Ohno, Akihisa, Matsumoto, Kazuhide, Teramatsu, Katsuhito, Takamatsu, Yu, Takeno, Ayumu, Oono, Takamasa, Abe, Toshiya, Ideno, Noboru, Ikenaga, Naoki, Nakata, Kohei, Nakamura, Masafumi, Ishigami, Kousei, Ogawa, Yoshihiro

“…Background/Aims Recently neoadjuvant chemotherapy (NAC) for pancreatic cancer has been shown to be superior to upfront surgery, but it remains a matter of…”
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Role of endoscopic retrograde pancreatography for early detection of pancreatic ductal adenocarcinoma concomitant with intraductal papillary mucinous neoplasm of the pancreas by Ohtsuka, Takao, Ideno, Noboru, Aso, Teppei, Nagayoshi, Yosuke, Kono, Hiroshi, Mori, Yasuhisa, Takahata, Shunichi, Oda, Yasunori, Aishima, Shinichi, Igarashi, Hisato, Ito, Tetsuhide, Ishigami, Kousei, Nakamura, Masafumi, Mizumoto, Kazuhiro, Tanaka, Masao

“…Background Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is often found with distinct pancreatic ductal adenocarcinoma (PDAC) in the same…”
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Diagnostic significance of a dilated orifice of the duodenal papilla in intraductal papillary mucinous neoplasm of the pancreas by Aso, Teppei, MD, Ohtsuka, Takao, MD, Ideno, Noboru, MD, Kono, Hiroshi, MD, Nagayoshi, Yosuke, MD, Mori, Yasuhisa, MD, Ohuchida, Kennoki, MD, Ueda, Junji, MD, Takahata, Shunnichi, MD, Morimatsu, Katsuya, MD, Aishima, Shinichi, MD, Igarashi, Hisato, MD, Ito, Tetsuhide, MD, Ishigami, Kousei, MD, Mizumoto, Kazuhiro, MD, Tanaka, Masao, MD

“…Background A dilated orifice of the duodenal papilla found during screening endoscopy or ERCP is well-known as one of the specific findings of intraductal…”
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A minimally invasive and simple screening test for detection of pancreatic ductal adenocarcinoma using biomarkers in duodenal juice by Mori, Yasuhisa, Ohtsuka, Takao, Kono, Hiroshi, Nagayoshi, Yosuke, Ideno, Noboru, Aso, Teppei, Kozono, Shingo, Ohuchida, Kenoki, Takahata, Shunichi, Nakamura, Masafumi, Mizumoto, Kazuhiro, Tanaka, Masao

“…The aim of this study was to establish a minimally invasive and simple screening test for detection of pancreatic ductal adenocarcinoma (PDAC) using duodenal…”
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Expression of glucagon-like Peptide 1 receptor and its effects on biologic behavior in pancreatic neuroendocrine tumors by Cases, Ana Ines, Ohtsuka, Takao, Fujino, Minoru, Ideno, Noboru, Kozono, Shingo, Zhao, Ming, Ohuchida, Kenoki, Aishima, Shinichi, Nomura, Masatoshi, Oda, Yoshinao, Mizumoto, Kazuhiro, Tanaka, Masao

“…Glucagon-like peptide 1 (GLP-1) interacts with its specific high-affinity receptor, glucagon-like peptide 1 receptor (GLP-1R), and induces cellular growth and…”
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