Search Results - "Ideno, Hisashi"

Tooth transplantation and replantation: Biological insights towards therapeutic improvements by Ideno, Hisashi, Komatsu, Koichiro, Nakashima, Kazuhisa, Nifuji, Akira

“…Summary Transplantation and replantation of teeth are effective therapeutic approaches for tooth repositioning and avulsion, respectively. Transplantation…”
Get full text

Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells by Araki, Ryoko, Uda, Masahiro, Hoki, Yuko, Sunayama, Misato, Nakamura, Miki, Ando, Shunsuke, Sugiura, Mayumi, Ideno, Hisashi, Shimada, Akemi, Nifuji, Akira, Abe, Masumi

“…Immune rejection may limit the therapeutic use of induced pluripotent stem cells (iPSCs); here, terminally differentiated mouse iPSCs are shown to generate…”
Get full text

Platelet-derived growth factor-BB regenerates functional periodontal ligament in the tooth replantation by Komatsu, Koichiro, Ideno, Hisashi, Shibata, Tatsuya, Nakashima, Kazuhisa, Nifuji, Akira

“…Tooth ankylosis is a pathological condition of periodontal ligament (PDL) restoration after tooth replantation. Platelet-derived growth factor-BB (PDGF-BB) has…”
Get full text

The histone H3K9 methyltransferase G9a regulates tendon formation during development by Wada, Satoshi, Ideno, Hisashi, Nakashima, Kazuhisa, Komatsu, Koichiro, Demura, Noboru, Tomonari, Hiroshi, Kimura, Hiroshi, Tachibana, Makoto, Nifuji, Akira

“…G9a is a histone methyltransferase that catalyzes the methylation of histone 3 lysine 9 (H3K9), which is involved in the regulation of gene expression. We had…”
Get full text

G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development by Ideno, Hisashi, Nakashima, Kazuhisa, Komatsu, Koichiro, Araki, Ryoko, Abe, Masumi, Arai, Yoshinori, Kimura, Hiroshi, Shinkai, Yoichi, Tachibana, Makoto, Nifuji, Akira

“…The methyltransferase G9a was originally isolated as a histone methyltransferase that catalyzes the methylation of histone 3 lysine 9 (H3K9) to a dimethylated…”
Get full text

Annexin A5 Involvement in Bone Overgrowth at the Enthesis by Shimada, Akemi, Ideno, Hisashi, Arai, Yoshinori, Komatsu, Koichiro, Wada, Satoshi, Yamashita, Teruhito, Amizuka, Norio, Pöschl, Ernst, Brachvogel, Bent, Nakamura, Yoshiki, Nakashima, Kazuhisa, Mizukami, Hiroaki, Ezura, Yoichi, Nifuji, Akira

“…ABSTRACT Little is known about the molecular mechanisms of enthesis formation in mature animals. Here, we report that annexin A5 (Anxa5) plays a critical role…”
Get full text

Alendronate promotes bone formation by inhibiting protein prenylation in osteoblasts in rat tooth replantation model by Komatsu, Koichiro, Shimada, Akemi, Shibata, Tatsuya, Wada, Satoshi, Ideno, Hisashi, Nakashima, Kazuhisa, Amizuka, Norio, Noda, Masaki, Nifuji, Akira

“…Bisphosphonates (BPs) are a major class of antiresorptive drug, and their molecular mechanisms of antiresorptive action have been extensively studied. Recent…”
Get full text

Essential roles of G9a in cell proliferation and differentiation during tooth development by Kamiunten, Taichi, Ideno, Hisashi, Shimada, Akemi, Arai, Yoshinori, Terashima, Tatsuo, Tomooka, Yasuhiro, Nakamura, Yoshiki, Nakashima, Kazuhisa, Kimura, Hiroshi, Shinkai, Yoichi, Tachibana, Makoto, Nifuji, Akira

“…Teeth develop through interactions between epithelial and mesenchymal tissues mediated by a signaling network comprised of growth factors and transcription…”
Get full text

Coordinated expression of H3K9 histone methyltransferases during tooth development in mice by Kamiunten, Taichi, Ideno, Hisashi, Shimada, Akemi, Nakamura, Yoshiki, Kimura, Hiroshi, Nakashima, Kazuhisa, Nifuji, Akira

“…Tissue-specific gene expression is subjected to epigenetic and genetic regulation. Posttranslational modifications of histone tails alter the accessibility of…”
Get full text

H3K9MTase G9a is essential for the differentiation and growth of tenocytes in vitro by Wada, Satoshi, Ideno, Hisashi, Shimada, Akemi, Kamiunten, Taichi, Nakamura, Yoshiki, Nakashima, Kazuhisa, Kimura, Hiroshi, Shinkai, Yoichi, Tachibana, Makoto, Nifuji, Akira

“…Cell differentiation is controlled by specific transcription factors. The functions and expression levels of these transcription factors are regulated by…”
Get full text

Efficient expansion of mouse primary tenocytes using a novel collagen gel culture method by Shimada, Akemi, Wada, Satoshi, Inoue, Kouji, Ideno, Hisashi, Kamiunten, Taichi, Komatsu, Koichiro, Kudo, Akira, Nakamura, Yoshiki, Sato, Tetsuji, Nakashima, Kazuhisa, Nifuji, Akira

“…Development of regenerative therapies for damaged tendons remains a great challenge, largely because of lack of information regarding the mechanisms…”
Get full text

Protein related to DAN and cerberus (PRDC) inhibits osteoblastic differentiation and its suppression promotes osteogenesis in vitro by Ideno, Hisashi, Takanabe, Rieko, Shimada, Akemi, Imaizumi, Kazuhiko, Araki, Ryoko, Abe, Masumi, Nifuji, Akira

“…Protein related to DAN and cerberus (PRDC) is a secreted protein characterized by a cysteine knot structure, which binds bone morphogenetic proteins (BMPs) and…”
Get full text

Roles of the histone methyltransferase G9a in the development and differentiation of mesenchymal tissues by Hisashi Ideno, Kazuhisa Nakashima, Akira Nifuji

“…The expression of cell lineage-specific genes during cell differentiation and development is regulated by lineage-specific transcription factors. Recent…”
Get full text

Age-related effects of fasting on ketone body production during lipolysis in rats by Higashino-Matsui, Yuriko, Shirato, Ken, Suzuki, Yuko, Kawashima, Yu, Someya, Yui, Sato, Shogo, Shiraishi, Akira, Jinde, Manabu, Matsumoto, Akiko, Ideno, Hisashi, Tachiyashiki, Kaoru, Imaizumi, Kazuhiko

“…The age-related effects of fasting on lipolysis, the production of ketone bodies, and plasma insulin levels were studied in male 3-, 8-, and 32-week-old…”
Get full text

Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development by Ideno, Hisashi, Shimada, Akemi, Imaizumi, Kazuhiko, Kimura, Hiroshi, Abe, Masumi, Nakashima, Kazuhisa, Nifuji, Akira

“…Schematic model of localizations of H3K9MTase and H3K9 modifications in growth plate development. Proliferative (Pro), prehypertrophic (Prhy) and hypertrophic…”
Get full text

Single administration effects of ethanol on the distribution of white blood cells in rats by Kawashima, Yu, Someya, Yui, Shirato, Ken, Sato, Shogo, Ideno, Hisashi, Kobayashi, Kyoko, Tachiyashiki, Kaoru, Imaizumi, Kazuhiko

“…Acute single administration effects of ethanol on the distribution of total white blood cells (WBCs), neutrophil, basophil, eosinophil, monocyte and…”
Get full text

Extracellular Modulators Regulate Bone Morphogenic Proteins in Skeletal Tissue by Nifuji, Akira, Ideno, Hisashi, Takanabe, Rieko, Noda, Masaki

“…Bone morphogenic proteins (BMP) are multifunctional growth factors and members of the TGF-β superfamily. They were identified based on their ability to…”
Get full text

Dietary zinc-deficiency and its recovery responses in the thermogenesis of rats by Sakakibara, Yuko, Sato, Shogo, Shirato, Ken, Arai, Natsuko, Aritoshi, Shoko, Ogawa-Nakata, Naho, Kawashima, Yu, Someya, Yui, Akimoto, Shunta, Jinde, Manabu, Shiraishi, Akira, Ideno, Hisashi, Tachiyashiki, Kaoru, Imaizumi, Kazuhiko

“…The aim of this study was to elucidate whether dietary zinc-deficiency and its recovery play a role in controlling autonomic thermoregulation. We investigated…”
Get full text

The G9a histone methyltransferase represses osteoclastogenesis and bone resorption by regulating NFATc1 function by Komatsu, Koichiro, Ideno, Hisashi, Nakashima, Kazuhisa, Udagawa, Nobuyuki, Kobayashi, Yasuhiro, Kimura, Hiroshi, Tachibana, Makoto, Yamashita, Teruhito, Nifuji, Akira

“…Epigenetic modifications affect cell differentiation via transcriptional regulation. G9a/EHMT2 is an important epigenetic modifier that catalyzes the…”
Get full text

Corrigendum to “G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development” [Bone 137 (2020) 115332] by Ideno, Hisashi, Nakashima, Kazuhisa, Komatsu, Koichiro, Araki, Ryoko, Abe, Masumi, Arai, Yoshinori, Kimura, Hiroshi, Shinkai, Yoichi, Tachibana, Makoto, Nifuji, Akira

Get full text