Search Results - "Idei, Akiko"

Synergistic involvement of the NZF domains of the LUBAC accessory subunits HOIL-1L and SHARPIN in the regulation of LUBAC function by Toda, Yusuke, Fujita, Hiroaki, Mino, Koshiki, Koyama, Takuto, Matsuoka, Seiji, Kaizuka, Toshie, Agawa, Mari, Matsumoto, Shigeyuki, Idei, Akiko, Nishikori, Momoko, Okuno, Yasushi, Osada, Hiroyuki, Yoshida, Minoru, Takaori-Kondo, Akifumi, Iwai, Kazuhiro

“…The linear ubiquitin chain assembly complex (LUBAC) plays crucial roles in NF-κB signaling and protection against cell death by generating linear ubiquitin…”
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Discovery of evocalcet, a next-generation calcium-sensing receptor agonist for the treatment of hyperparathyroidism by Miyazaki, Hiroshi, Ikeda, Yousuke, Sakurai, Osamu, Miyake, Tsutomu, Tsubota, Rie, Okabe, Jyunko, Kuroda, Masataka, Hisada, Yutaka, Yanagida, Tetsuya, Yoneda, Hikaru, Tsukumo, Yukihito, Tokunaga, Shin, Kawata, Takehisa, Ohashi, Rikiya, Fukuda, Hajime, Kojima, Koki, Kannami, Ayako, Kifuji, Takayuki, Sato, Naoya, Idei, Akiko, Iguchi, Taku, Sakairi, Tetsuya, Moritani, Yasunori

“…[Display omitted] •Optimization from cinacalcet resulted in the discovery of evocalcet.•CYP2D6 inhibition observed in cinacalcet is completely solved in…”
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Gram-negative bacterial atp-binding cassette protein exporter family and diverse secretory proteins by Omori, Kenji, Idei, Akiko

“…Protein translocation to the extracellular space is essential for the invasion, colonization, and survival of pathogenic gram-negative bacteria within a host…”
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Serratia ATP-binding Cassette Protein Exporter, Lip, Recognizes a Protein Region Upstream of the C Terminus for Specific Secretion by Omori, Kenji, Idei, Akiko, Akatsuka, Hiroyuki

“…Serratia marcescensATP-binding cassette (ABC) exporter, the Lip system, secretes lipase (LipASM), metalloproteases, and a cell surface layer protein homologue…”
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Discovery of Clinical Candidate AZD5462, a Selective Oral Allosteric RXFP1 Agonist for Treatment of Heart Failure by Granberg, Kenneth L., Sakamaki, Shigeki, Larsson, Niklas, Bergström, Fredrik, Fuchigami, Ryuichi, Niwa, Yasuki, Ryberg, Erik, Backmark, Anna, Kato, Harutoshi, Miyazaki, Shiki, Iguchi, Kaori, Sakamoto, Toshiaki, Persson, Mikael, Idei, Akiko, Prieto Garcia, Luna, Villar, Inmaculada C., Gradén, Henrik, Bergonzini, Giulia, Arvidsson, Torbjörn, Fujita, Takuya, Althage, Magnus, Ulander, Johan, Kimura, Junpei, Yoneda, Hikaru, Fjellström, Ola, Mochida, Hideki, Lal, Mark

“…Optimization of the highly potent and selective, yet metabolically unstable and poorly soluble hRXFP1 agonist AZ7976 led to the identification of the clinical…”
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Isolation and analysis of lipase-overproducing mutants of Serratia marcescens by Kawai, Eri, Akatsuka, Hiroyuki, Sakurai, Naoki, Idei, Akiko, Matsumae, Hiroaki, Shibatani, Takeji, Komatsubara, Saburo, Omori, Kenji

“…We have isolated a lipase-overproducing mutant, GE14, from Serratia marcescens 8000 after three rounds of N-methyl- N′-nitro- N-nitrosoguanidine mutagenesis…”
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Serratia marcescens S‐layer protein is secreted extracellularly via an ATP‐binding cassette exporter, the Lip system by Kawai, Eri, Akatsuka, Hiroyuki, Idei, Akiko, Shibatani, Takeji, Omori, Kenji

“…The Serratia marcescens Lip exporter belonging to the ATP‐binding cassette (ABC) exporter is known to be involved in signal peptide‐independent extracellular…”
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Cloning and characterization of the Pseudomonas fluorescens ATP-binding cassette exporter, HasDEF, for the heme acquisition protein HasA by Idei, A, Kawai, E, Akatsuka, H, Omori, K

“…Two ATP-binding cassette (ABC) exporters are present in Pseudomonas fluorescens no. 33; one is the recently reported AprDEF system and the other is HasDEF,…”
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Cloning and Characterization of thePseudomonas fluorescens ATP-Binding Cassette Exporter, HasDEF, for the Heme Acquisition Protein HasA by Akiko Idei, Eri Kawai, Hiroyuki Akatsuka, Kenji Omori

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The ABC-exporter genes involved in the lipase secretion are clustered with the genes for lipase, alkaline protease, and serine protease homologues in Pseudomonas fluorescens no. 33 by Kawai, Eri, Idei, Akiko, Kumura, Haruto, Shimazaki, Kei-ichi, Akatsuka, Hiroyuki, Omori, Kenji

“…In Pseudomonas fluorescens no. 33, the lipase gene is clustered with the genes for alkaline protease, AprDEF exporter, and two homologue proteins of Serratia…”
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