Search Results - "Ida, Satoru"
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Identification of Highly Selective Inhibitors of Collagenase-1 from Combinatorial Libraries of Diketopiperazines
Published in Journal of medicinal chemistry (22-04-1999)“…Thiol-containing diketopiperazines have been recently identified as novel heterocyclic inhibitors of matrix metalloproteinase (MMPs). The compounds described…”
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Malonyl α-mercaptoketones and α-mercaptoalcohols, a new class of matrix metalloproteinase inhibitors
Published in Bioorganic & medicinal chemistry letters (19-05-1998)“…A novel series of matrix metalloproteinase (MMP) inhibitors is described. Incorporation of a terminal α-mercaptoketone or α-mercaptoalcohol in the zinc binding…”
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Preparation of N-alkylated 5-oxo-3-carboxamyl-1,4-thiazinanes on solid support
Published in Molecular diversity (01-01-1998)“…A general method was developed to generate six-membered cyclic thiazinanes on solid support. Three diversity sites were introduced into this scaffold using…”
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