Search Results - "Id Said, Badr"
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Outcomes for oligometastatic head and neck cancer treated with stereotactic body radiotherapy: Results from an international multi‐institutional consortium
Published in Head & neck (01-10-2023)“…Abstract Background We report the results of an international multi‐institutional cohort of oligometastatic (OMD) head and neck cancer (HNC) patients treated…”
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Demographics, pattern of practice and clinical outcomes in rectal squamous cell carcinoma
Published in Colorectal disease (01-04-2023)“…Aim The aim of this study was to describe the baseline clinical features, treatment patterns and outcomes in rectal squamous cell carcinoma (SCC). Method This…”
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Stereotactic Body Radiotherapy for Extracranial Oligometastatic Disease from Head and Neck Primary Cancers: A Systematic Review and Meta-Analysis
Published in Cancers (20-02-2024)“…Stereotactic body radiotherapy (SBRT) is increasingly used to treat disease in the oligometastatic (OM) setting due to mounting evidence demonstrating its…”
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Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors
Published in Science (American Association for the Advancement of Science) (31-08-2018)“…Sarcomas are cancers of the bone and soft tissue often defined by gene fusions. Ewing sarcoma involves fusions between , a gene encoding an RNA binding…”
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Treatment Patterns and Outcomes of Women with Symptomatic and Asymptomatic Breast Cancer Brain Metastases: A Single‐Center Retrospective Study
Published in The oncologist (Dayton, Ohio) (01-11-2021)“…Background Breast cancer is the most common cancer among women worldwide and the second leading cause of brain metastases (BrM). We assessed the treatment…”
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Trastuzumab emtansine increases the risk of stereotactic radiosurgery-induced radionecrosis in HER2 + breast cancer
Published in Journal of neuro-oncology (01-08-2022)“…Introduction In this study, we investigate factors associated with radionecrosis (RN) in HER2 + (human epidermal growth factor receptor 2) patients with brain…”
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Patterns of treatment and outcomes of patients with brain-only metastatic breast cancer
Published in Journal of neuro-oncology (01-09-2023)“…Background We characterized the risk factors and survival of metastatic breast cancer (MBC) patients with brain metastases (BrM) as the first and only site of…”
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A functional variant in miR-605 modifies the age of onset in Li-Fraumeni syndrome
Published in Cancer genetics (01-01-2015)“…Li-Fraumeni syndrome (LFS) is a rare cancer predisposition syndrome, typically associated with germline mutations in the TP53 gene. Despite the high…”
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Super-Transactivation TP53 Variant in the Germline of a Family with Li-Fraumeni Syndrome
Published in Human mutation (01-09-2016)“…ABSTRACT Li–Fraumeni Syndrome (LFS) is a rare autosomal dominant familial cancer syndrome, characterized by multiple malignancies and frequent germline…”
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Development and Validation of an Oral Cavity Cancer Outcomes Prediction Score Incorporating Patient-Derived Xenograft Engraftment
Published in JAMA otolaryngology-- head & neck surgery (01-04-2022)“…Patient-derived xenografts (PDXs) offer the opportunity to identify patients with oral cavity squamous cell carcinoma (OSCC) who are at risk for recurrence and…”
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Genome-Wide DNA Methylation Analysis Reveals Epigenetic Dysregulation of MicroRNA-34A in TP53-Associated Cancer Susceptibility
Published in Journal of clinical oncology (20-10-2016)“…Although the link between mutant TP53 and human cancer is unequivocal, a significant knowledge gap exists in clinically actionable molecular targets in…”
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Transcriptome-wide characterization of the endogenous miR-34A-p53 tumor suppressor network
Published in Oncotarget (02-08-2016)“…microRNA-34A is a critical component of the p53 network and expression of miR- 34A is down-regulated by promoter hypermethylation or focal deletions in…”
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Cancer Patient-Reported Preferences and Knowledge for Liquid Biopsies and Blood Biomarkers at a Comprehensive Cancer Center
Published in Cancer management and research (01-02-2020)“…Blood-based biomarkers (liquid biopsy) are increasingly used in precision oncology. Yet, little is known about cancer patients' perspectives in clinical…”
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158 Patterns of Treatment and Outcomes of Patients with Brain-Only Metastatic Breast Cancer
Published in Radiotherapy and oncology (01-09-2023)Get full text
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Predictors of brain metastases in patients with oligometastatic solid tumours treated with stereotactic body radiation therapy
Published in Journal of neuro-oncology (04-10-2024)“…In patients with oligometastatic disease (OMD) treated with stereotactic body radiation therapy (SBRT), those who develop brain metastases (BrM) may have poor…”
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158: T-DM1 Increases the Risk of SRS-Induced Radiation Necrosis in HER2 + Breast Cancer
Published in Radiotherapy and oncology (01-10-2021)Get full text
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133 Hypofractionated Radiotherapy for the Definitive Management of Locally Advanced Non-Small Cell Lung Cancer: A Systematic Review
Published in Radiotherapy and oncology (01-09-2024)Get full text
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Individualized prediction of distant metastases risk in oral cavity carcinoma: A validated predictive-score model
Published in Journal of clinical oncology (01-06-2022)“…6037 Background: We aimed to develop and validate a risk-scoring system for distant metastases (DM) in oral cavity carcinoma (OCC). Methods: In this…”
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