Search Results - "Ichikawa, Kosuke"
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Measurements of Thermodynamic Data of Water in Ca-Bentonite by Relative Humidity Method
Published in Minerals (Basel) (01-05-2024)“…Buffer material (compacted bentonite), one of the engineered barrier elements in the geological disposal of a high-level radioactive waste, develops swelling…”
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Combination therapy of cisplatin with cilastatin enables an increased dose of cisplatin, enhancing its antitumor effect by suppression of nephrotoxicity
Published in Scientific reports (12-01-2021)“…Cisplatin, one of the most active anticancer agents, is widely used in standard chemotherapy for various cancers. Cisplatin is more poorly tolerated than other…”
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Observational study of rebiopsy in EGFR-TKI-resistant patients with EGFR mutation-positive advanced NSCLC
Published in Scientific reports (16-04-2022)“…The identification of acquired resistance mutations has been essential in non-small-cell lung cancer (NSCLC) patients with epidermal growth factor receptor…”
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Disseminated Varicella-zoster Virus Infection Causing Fatal Pneumonia in an Immunocompromised Patient with Chronic Interstitial Pneumonia
Published in Internal Medicine (01-04-2021)“…Viral pneumonia caused by varicella-zoster virus (VZV) infection is a rare but important complication, especially regarding varicella infections. Although…”
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Clinical responses to EGFR-tyrosine kinase inhibitor retreatment in non-small cell lung cancer patients who benefited from prior effective gefitinib therapy: a retrospective analysis
Published in BMC cancer (01-01-2011)“…Gefitinib was the first epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) approved for the treatment of advanced non-small cell lung cancer…”
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Retrospective analysis of antitumor effects and biomarkers for nivolumab in NSCLC patients with EGFR mutations
Published in PloS one (12-04-2019)“…Although the blockade of programmed cell death 1 (PD-1)/PD-ligand (L) 1 has demonstrated promising and durable clinical responses for non-small-cell lung…”
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Prospective assessment using 18F-FDG PET/CT as a novel predictor for early response to PD-1 blockade in non-small-cell lung cancer
Published in Scientific reports (12-07-2022)“…Anti-programmed death-1 (PD-1) blockade is a standard treatment for advanced non-small-cell lung cancer (NSCLC). However, no appropriate modality exists for…”
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PD-1 blockade therapy augments the antitumor effects of lymphodepletion and adoptive T cell transfer
Published in Cancer Immunology, Immunotherapy (01-06-2022)“…Lymphodepleting cytotoxic regimens enhance the antitumor effects of adoptively transferred effector and naïve T cells. Although the mechanisms of antitumor…”
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HER3 activation contributes toward the emergence of ALK inhibitor-tolerant cells in ALK-rearranged lung cancer with mesenchymal features
Published in NPJ precision oncology (18-01-2022)“…Anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) have shown dramatic efficacy in patients with ALK-rearranged lung cancer; however, complete…”
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The Prognostic Significance of the Continuous Administration of Anti-PD-1 Antibody via Continuation or Rechallenge After the Occurrence of Immune-Related Adverse Events
Published in Frontiers in oncology (24-09-2021)“…Although immune checkpoint inhibitors (ICIs) have been shown to improve overall survival (OS) in advanced non-small-cell lung cancer (NSCLC) patients, ICIs…”
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Prognostic significance of procalcitonin in small cell lung cancer
Published in Translational lung cancer research (01-01-2022)Get full text
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Comparative analysis of different response criteria at early phase after PD-1 blockade in non-small lung cancer
Published in Cancer imaging (01-03-2023)“…To compare different response criteria using computed tomography (CT) and positron emission tomography (PET) in measuring response and survival in the early…”
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Prognostic significance of the radiologic features of pneumonitis induced by anti‐PD‐1 therapy
Published in Cancer medicine (Malden, MA) (01-05-2020)“…Background Interstitial lung disease (ILD) induced by anti‐programmed‐cell death‐1 (PD‐1) and anti‐PD‐ligand 1 (PD‐L1) is potentially life‐threatening and is a…”
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Transfer of in vitro-expanded naïve T cells after lymphodepletion enhances antitumor immunity through the induction of polyclonal antitumor effector T cells
Published in PloS one (30-08-2017)“…The adoptive transfer of effector T cells combined with lymphodepletion has demonstrated promising antitumor effects in mice and humans, although the…”
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Efficacy of EGFR‐TKIs with or without upfront brain radiotherapy for EGFR‐mutant NSCLC patients with central nervous system metastases
Published in Thoracic cancer (01-11-2019)“…Background Although the clinical efficacy of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR‐TKIs) in EGFR‐mutant non‐small cell lung cancer…”
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Development of a video image‐based QA system for the positional accuracy of dynamic tumor tracking irradiation in the Vero4DRT system
Published in Medical physics (Lancaster) (01-08-2015)“…Purpose: To develop and evaluate a new video image‐based QA system, including in‐house software, that can display a tracking state visually and quantify the…”
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Frequent Germline and Somatic Single Nucleotide Variants in the Promoter Region of the Ribosomal RNA Gene in Japanese Lung Adenocarcinoma Patients
Published in Cells (Basel, Switzerland) (03-11-2020)“…Ribosomal RNA (rRNA), the most abundant non-coding RNA species, is a major component of the ribosome. Impaired ribosome biogenesis causes the dysfunction of…”
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Hypertrophic Pulmonary Osteoarthropathy in Anaplastic Lymphoma Kinase (ALK)-positive Lung Cancer
Published in Internal Medicine (01-01-2015)“…A 49-year-old man was admitted to a hospital with chest pain and polyarthralgia. Chest radiography showed abnormal findings, and chest computed tomography…”
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Epitope diversification driven by non-tumor epitope-specific Th1 and Th17 mediates potent antitumor reactivity
Published in Vaccine (21-09-2012)“…Highlights ► Non tumor-specific CD4+ T cells can induce tumor antigen presentation by DC. ► Th1 and Th17, but not Th2 facilitated diverse tumor antigen…”
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