Search Results - "Ichijo, Kazuki"
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Quantitative analysis of gastrointestinal fluid absorption and secretion to estimate luminal fluid dynamics in rats
Published in Scientific reports (14-10-2023)“…The drug absorption profile is dependent on the luminal drug concentration, which in turn is influenced by the gastrointestinal (GI) fluid dynamics. In the…”
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Effect of Osmolality on the Pharmacokinetic Interaction between Apple Juice and Atenolol in Rats
Published in Drug metabolism and disposition (01-04-2019)“…A recent clinical study reported that the ingestion of apple juice (AJ) markedly reduced the plasma concentration of atenolol; however, our in vitro study…”
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Osmolality of Orally Administered Solutions Influences Luminal Water Volume and Drug Absorption in Intestine
Published in Journal of pharmaceutical sciences (01-09-2017)“…Intestinal water absorption is reportedly influenced by luminal osmolality. In this study, we examined whether differences in the osmolality of the vehicle…”
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