Search Results - "Ichihara, Sahoko"

Environmental arsenic exposure and its contribution to human diseases, toxicity mechanism and management by Rahaman, Md. Shiblur, Rahman, Md. Mostafizur, Mise, Nathan, Sikder, Md. Tajuddin, Ichihara, Gaku, Uddin, Md. Khabir, Kurasaki, Masaaki, Ichihara, Sahoko

“…Arsenic is a well-recognized environmental contaminant that occurs naturally through geogenic processes in the aquifer. More than 200 million people around the…”
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Proteomic Profiling of Exosomal Proteins for Blood-based Biomarkers in Parkinson's Disease by Kitamura, Yuki, Kojima, Midori, Kurosawa, Toshihito, Sasaki, Ryogen, Ichihara, Sahoko, Hiraku, Yusuke, Tomimoto, Hidekazu, Murata, Mariko, Oikawa, Shinji

“…•CLU, C1R, and APOA1 in exosomes were decreased in PD at HY stages II and III.•Expression levels of APOA1 in exosomes reduced in correlation with severity of…”
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Particle toxicology and health - where are we? by Riediker, Michael, Zink, Daniele, Kreyling, Wolfgang, Oberdörster, Günter, Elder, Alison, Graham, Uschi, Lynch, Iseult, Duschl, Albert, Ichihara, Gaku, Ichihara, Sahoko, Kobayashi, Takahiro, Hisanaga, Naomi, Umezawa, Masakazu, Cheng, Tsun-Jen, Handy, Richard, Gulumian, Mary, Tinkle, Sally, Cassee, Flemming

“…Particles and fibres affect human health as a function of their properties such as chemical composition, size and shape but also depending on complex…”
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The pathological roles of environmental and redox stresses in cardiovascular diseases by Ichihara, Sahoko

“…Oxidative stress and inflammation are implicated in cardiovascular diseases such as atherosclerosis, reperfusion injury, hypertension, and heart failure. High…”
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The mechanism of low-level arsenic exposure-induced hypertension: Inhibition of the activity of the angiotensin-converting enzyme 2 by Rahaman, Md. Shiblur, Mise, Nathan, Ikegami, Akihiko, Zong, Cai, Ichihara, Gaku, Ichihara, Sahoko

“…It is now well-established that arsenic exposure induces hypertension in humans. Although arsenic-induced hypertension is reported in many epidemiological…”
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Role of microglial activation and neuroinflammation in neurotoxicity of acrylamide in vivo and in vitro by Zong, Cai, Hasegawa, Rieka, Urushitani, Makoto, Zhang, Lingyi, Nagashima, Daichi, Sakurai, Toshihiro, Ichihara, Sahoko, Ohsako, Seiichiroh, Ichihara, Gaku

“…Acrylamide, a soft electrophile, is widely used in the industry and laboratories, and also contaminates certain foods. Neurotoxicity and neurodegenerative…”
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Toxicological Evaluation of SiO₂ Nanoparticles by Zebrafish Embryo Toxicity Test by Vranic, Sandra, Shimada, Yasuhito, Ichihara, Sahoko, Kimata, Masayuki, Wu, Wenting, Tanaka, Toshio, Boland, Sonja, Tran, Lang, Ichihara, Gaku

“…As the use of nanoparticles (NPs) is increasing, the potential toxicity and behavior of NPs in living systems need to be better understood. Our goal was to…”
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Arsenic contamination in food chain in Bangladesh: A review on health hazards, socioeconomic impacts and implications by Rahaman, Md. Shiblur, Mise, Nathan, Ichihara, Sahoko

“…•Arsenic poisoning is not a local problem, it is a global public health concern.•Situation of Bangladesh is particularly devastating among all affected…”
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Plasma protein profiling for potential biomarkers in the early diagnosis of Alzheimer's disease by Kitamura, Yuki, Usami, Ryoko, Ichihara, Sahoko, Kida, Hirotaka, Satoh, Masayuki, Tomimoto, Hidekazu, Murata, Mariko, Oikawa, Shinji

“…Objectives: Alzheimer's disease (AD) is the most common cause of dementia in elderly persons. Since the pathology of AD develops slowly from a preclinical or…”
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Factory site analysis of respirable fibers generated during the process of cutting and grinding of carbon fibers-reinforced plastics by Kumoi, Jun, Ikegami, Akihiko, Fujitani, Yuji, Morikawa, Kota, Ichihara, Gaku, Yano, Takeo, Ichihara, Sahoko

“…Objectives Carbon fibers are used in a variety of industrial applications, based on their lightweight and high stiffness properties. There is little…”
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Proteomic identification of the proteins related to cigarette smoke-induced cardiac hypertrophy in spontaneously hypertensive rats by Kitamura, Yuki, Mise, Nathan, Mori, Yurie, Suzuki, Yuka, Ohashi, Tomoki, Tada-Oikawa, Saeko, Tokisu, Masaki, Zong, Cai, Oikawa, Shinji, Ichihara, Sahoko

“…Smoking increases the risk of cardiovascular diseases. The present study was designed to determine the effects of 2-month exposure to cigarette smoke (CS) on…”
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Evaluation of hydroxyapatite nanoparticles - induced in vivo toxicity in Drosophila melanogaster by Dan, Pallavi, Sundararajan, Vignesh, Ganeshkumar, Harsana, Gnanabarathi, Barathan, Subramanian, Arun Kumar, Venkatasubu, G. Devanand, Ichihara, Sahoko, Ichihara, Gaku, Sheik Mohideen, Sahabudeen

“…Hydroxyapatite (HAp), a compound similar in composition to human hard tissues such as bone and teeth, has widespread applications in bulk as well as…”
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Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice by Ekuban, Frederick Adams, Zong, Cai, Takikawa, Madoka, Morikawa, Kota, Sakurai, Toshihiro, Ichihara, Sahoko, Itoh, Ken, Yamamoto, Masayuki, Ohsako, Seiichiroh, Ichihara, Gaku

“…[Display omitted] •Deletion of Nrf2 gene enhanced acrylamide-induced neurotoxicity.•Deletion of Nrf2 gene enhanced acrylamide-induced microglial…”
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Proteomic analysis of liver proteins of mice exposed to 1,2-dichloropropane by Zhang, Xiao, Morikawa, Kota, Mori, Yurie, Zong, Cai, Zhang, Lingyi, Garner, Edwin, Huang, Chinyen, Wu, Wenting, Chang, Jie, Nagashima, Daichi, Sakurai, Toshihiro, Ichihara, Sahoko, Oikawa, Shinji, Ichihara, Gaku

“…1,2-Dichloropropane (1,2-DCP) is recognized as the causative agent for cholangiocarcinoma among offset color proof-printing workers in Japan. The aim of the…”
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Transcriptome analysis of human cholangiocytes exposed to carcinogenic 1,2-dichloropropane in the presence of macrophages in vitro by Ekuban, Abigail, Shichino, Shigeyuki, Zong, Cai, Ekuban, Frederick Adams, Kinoshita, Kazuo, Ichihara, Sahoko, Matsushima, Kouji, Ichihara, Gaku

“…1,2-Dichloropropane (1,2-DCP), a synthetic organic solvent, has been implicated in causality of cholangiocarcinoma (bile duct cancer). 1,2-DCP-induced…”
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Involvement of oxidative modification of proteins related to ATP synthesis in the left ventricles of hamsters with cardiomyopathy by Ichihara, Sahoko, Suzuki, Yuka, Chang, Jie, Kuzuya, Kentaro, Inoue, Chisa, Kitamura, Yuki, Oikawa, Shinji

“…Inflammation enhanced by accumulation of reactive oxygen species plays an essential role in the progression of cardiovascular diseases. Using the 2D-oxyblot…”
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Epigenome-wide association of myocardial infarction with DNA methylation sites at loci related to cardiovascular disease by Nakatochi, Masahiro, Ichihara, Sahoko, Yamamoto, Ken, Naruse, Keiko, Yokota, Shigeki, Asano, Hiroyuki, Matsubara, Tatsuaki, Yokota, Mitsuhiro

“…Development of cardiovascular disease (CVD), including coronary artery disease, arrhythmia, and ischemic stroke, depends on environmental and genetic factors…”
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Significant association of RNF213 p.R4810K, a moyamoya susceptibility variant, with coronary artery disease by Morimoto, Takaaki, Mineharu, Yohei, Ono, Koh, Nakatochi, Masahiro, Ichihara, Sahoko, Kabata, Risako, Takagi, Yasushi, Cao, Yang, Zhao, Lanying, Kobayashi, Hatasu, Harada, Kouji H, Takenaka, Katsunobu, Funaki, Takeshi, Yokota, Mitsuhiro, Matsubara, Tatsuaki, Yamamoto, Ken, Izawa, Hideo, Kimura, Takeshi, Miyamoto, Susumu, Koizumi, Akio

“…The genetic architecture of coronary artery disease has not been fully elucidated, especially in Asian countries. Moyamoya disease is a progressive…”
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Protective role of Nrf2 in zinc oxide nanoparticles-induced lung inflammation in female mice and sexual dimorphism in susceptibility by Sehsah, Radwa, Wu, Wenting, Ichihara, Sahoko, Hashimoto, Naozumi, Zong, Cai, Yamazaki, Kyoka, Sato, Harue, Itoh, Ken, Yamamoto, Masayuki, Elsayed, Ahmed Ali, El-Bestar, Soheir, Kamel, Emily, Ichihara, Gaku

“…BACKGROUNDZinc oxide nanoparticles (ZnO-NPs) are currently employed in various products such as rubber, paint, and cosmetics. Our group reported recently that…”
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Long‐Chain Acyl Carnitines Aggravate Polystyrene Nanoplastics‐Induced Atherosclerosis by Upregulating MARCO by Wang, Bo, Liang, Boxuan, Huang, Yuji, Li, Zhiming, Zhang, Bingli, Du, Jiaxin, Ye, Rongyi, Xian, Hongyi, Deng, Yanhong, Xiu, Jiancheng, Yang, Xingfen, Ichihara, Sahoko, Ichihara, Gaku, Zhong, Yizhou, Huang, Zhenlie

“…Exposure to micro‐ and nanoplastics (MNPs) is common because of their omnipresence in environment. Recent studies have revealed that MNPs may cause…”
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