Search Results - "Ichi, Ikuyo"

The effect of polyunsaturated fatty acid deficiency on allergic response in ovalbumin-immunized mice by Hayashi, Yuri, Yokomizo, Yuka, Fujiwara, Yoko, Ichi, Ikuyo

“…•A PUFA-deficient diet did not worsen allergies in ovalbumin-immunized [OVA(+)] mice.•Serum PUFA levels were similar in OVA(+) and OVA(–) mice fed a…”
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Effect of tocotrienol on the primary progression of nonalcoholic steatohepatitis in a mouse model by Noichi, Jun, Ishiakawa, Tomoko, Ichi, Ikuyo, Fujiwara, Yoko

“…Tocotrienol (T3), a vitamin E (Vit E) isoform, is known to have both biological and antioxidant effects. Although alpha-tocopherol (α-Toc), another isoform of…”
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Effects of Vitamin E and Dietary Conditions on the Differentiation and Maturation of Osteoclast by FUJIWARA, Yoko, KO, Yuko, SONODA, Mariko, ICHI, Ikuyo, ISHIKAWA, Tomoko

“…α-Tocopherol is reported to activate the differentiation and fusion of osteoclast, however, it is not clear whether the excessive intake of vitamin E is a risk…”
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GPER/PKA-Dependent Enhancement of Hormone-Sensitive Lipase Phosphorylation in 3T3-L1 Adipocytes by Piceatannol by Arisawa, Kotoko, Matsuoka, Ayumi, Ozawa, Natsuki, Ishikawa, Tomoko, Ichi, Ikuyo, Fujiwara, Yoko

“…We previously reported that piceatannol (PIC) had an anti-obesity effect only in ovariectomized (OVX) postmenopausal obesity mice. PIC was found to induce the…”
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Ablation of fatty acid desaturase 2 (FADS2) exacerbates hepatic triacylglycerol and cholesterol accumulation in polyunsaturated fatty acid‐depleted mice by Hayashi, Yuri, Lee‐Okada, Hyeon‐Cheol, Nakamura, Eri, Tada, Norihiro, Yokomizo, Takehiko, Fujiwara, Yoko, Ichi, Ikuyo, Nagy, László

“…Deficiency of polyunsaturated fatty acids (PUFAs) is known to induce hepatic steatosis. However, it is not clearly understood which type of PUFA is responsible…”
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Dietary 7-ketocholesterol exacerbates myocardial ischemia–reperfusion injury in mice through monocyte/macrophage-mediated inflammation by Uchikawa, Tomoki, Matoba, Tetsuya, Kawahara, Takuro, Baba, Isashi, Katsuki, Shunsuke, Koga, Jun-ichiro, Hashimoto, Yu, Yamasaki, Ryo, Ichi, Ikuyo, Akita, Hidetaka, Tsutsui, Hiroyuki

“…Emerging evidence suggests that 7-ketocholesterol (7-KC), one of the most abundant dietary oxysterols, causes inflammation and cardiovascular diseases. Here we…”
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Impact of the COVID‐19 pandemic on the glycemic control, eating habits, and body compositions of people with diabetes mellitus: A retrospective longitudinal observational study by Sawada, Mika, Ohkuma, Kanako, Aihara, Masakazu, Doi, Shunsuke, Sekine, Rie, Kaneko, Tetsuji, Iimuro, Satoshi, Ichi, Ikuyo, Usami, Satoshi, Ohe, Kazuhiko, Yamauchi, Toshimasa, Kubota, Naoto

“…ABSTRACT Aims/Introduction To evaluate the impact of the COVID‐19 pandemic on the glycemic control, eating habits, and body composition of people with diabetes…”
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Piceatannol Prevents Obesity and Fat Accumulation Caused by Estrogen Deficiency in Female Mice by Promoting Lipolysis by Arisawa, Kotoko, Kaneko, Miyuki, Matsuoka, Ayumi, Ozawa, Natsuki, Kawawa, Rie, Ishikawa, Tomoko, Ichi, Ikuyo, Fujiwara, Yoko

“…Postmenopausal women have a higher susceptibility to obesity and chronic disease. Piceatannol (PIC), a natural analog of resveratrol, was reported to inhibit…”
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Excretion of triacylglycerol as a matrix lipid facilitating apoplastic accumulation of a lipophilic metabolite shikonin by Tatsumi, Kanade, Ichino, Takuji, Isaka, Natsumi, Sugiyama, Akifumi, Moriyoshi, Eiko, Okazaki, Yozo, Higashi, Yasuhiro, Kajikawa, Masataka, Tsuji, Yoshinori, Fukuzawa, Hideya, Toyooka, Kiminori, Sato, Mayuko, Ichi, Ikuyo, Shimomura, Koichiro, Ohta, Hiroyuki, Saito, Kazuki, Yazaki, Kazufumi

“…Abstract Plants produce a large variety of lipophilic metabolites, many of which are secreted by cells and accumulated in apoplasts. These compounds often play…”
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Saturated fatty acid in the phospholipid monolayer contributes to the formation of large lipid droplets by Arisawa, Kotoko, Mitsudome, Haruka, Yoshida, Konomi, Sugimoto, Shizuka, Ishikawa, Tomoko, Fujiwara, Yoko, Ichi, Ikuyo

“…The degree of saturation of fatty acid chains in the bilayer membrane structure is known to control membrane fluidity and packing density. However, the…”
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Identification of genes and pathways involved in the synthesis of Mead acid (20:3n−9), an indicator of essential fatty acid deficiency by Ichi, Ikuyo, Kono, Nozomu, Arita, Yuka, Haga, Shizuka, Arisawa, Kotoko, Yamano, Misato, Nagase, Mana, Fujiwara, Yoko, Arai, Hiroyuki

“…In mammals, 5,8,11-eicosatrienoic acid (Mead acid, 20:3n−9) is synthesized from oleic acid during a state of essential fatty acid deficiency (EFAD). Mead acid…”
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Oleuropein improves insulin resistance in skeletal muscle by promoting the translocation of GLUT4 by Fujiwara, Yoko, Tsukahara, Chisato, Ikeda, Naoe, Sone, Yasuko, Ishikawa, Tomoko, Ichi, Ikuyo, Koike, Taisuke, Aoki, Yoshinori

“…As the beneficial effects of the Mediterranean diet on human health are well established, the phenolic compounds in olive oil have been gaining interest…”
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Cryo-EM analysis reveals human SID-1 transmembrane family member 1 dynamics underlying lipid hydrolytic activity by Hirano, Yoshinori, Ohto, Umeharu, Ichi, Ikuyo, Sato, Ryota, Miyake, Kensuke, Shimizu, Toshiyuki

“…Two mammalian homologs of systemic RNA interference defective protein 1 (SID-1) (SIDT1/2) are suggested to function as double-stranded RNA (dsRNA) transporters…”
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FADS2 inhibition in essential fatty acid deficiency induces hepatic lipid accumulation via impairment of very low-density lipoprotein (VLDL) secretion by Hayashi, Yuri, Shimamura, Ayano, Ishikawa, Tomoko, Fujiwara, Yoko, Ichi, Ikuyo

“…Fatty acid desaturase 2 (FADS2) is responsible for the first desaturation reaction in the synthesis of highly unsaturated fatty acids (HUFAs), such as…”
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Perilipin-mediated lipid droplet formation in adipocytes promotes sterol regulatory element-binding protein-1 processing and triacylglyceride accumulation by Takahashi, Yu, Shinoda, Akihiro, Furuya, Norihiko, Harada, Eri, Arimura, Naoto, Ichi, Ikuyo, Fujiwara, Yoko, Inoue, Jun, Sato, Ryuichiro

“…Sterol regulatory element-binding protein-1 (SREBP-1) has been thought to be a critical factor that assists adipogenesis. During adipogenesis SREBP-1…”
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A Dietary Oxysterol, 7-Ketocholesterol, Exacerbates Imiquimod-Induced Psoriasis-like Dermatitis in Steatohepatitic Mice by Saga, Ayami, Koseki, Masahiro, Kanno, Kotaro, Chang, Jiuyang, Higo, Tomoaki, Okuzaki, Daisuke, Okada, Takeshi, Inui, Hiroyasu, Asaji, Masumi, Tanaka, Katsunao, Omatsu, Takashi, Nishihara, Sae, Zhu, Yinghong, Ito, Kaori, Hattori, Hiroaki, Ichi, Ikuyo, Kamada, Yoshihiro, Ono, Masafumi, Saibara, Toshiji, Ohama, Tohru, Hikoso, Shungo, Nishida, Makoto, Yamashita, Shizuya, Sakata, Yasushi

“…Patients with psoriasis are at a higher risk of developing nonalcoholic fatty liver disease. We previously identified an oxidized derivative of cholesterol,…”
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Association between Serum Oxysterols and Coronary Plaque Regression during Lipid-Lowering Therapy with Statin and Ezetimibe: Insights from the CuVIC Trial by Nakano, Yasuhiro, Yamamoto, Mitsutaka, Matoba, Tetsuya, Katsuki, Shunsuke, Nakashiro, Soichi, Takase, Susumu, Akiyama, Yusuke, Nagata, Takuya, Mukai, Yasushi, Inoue, Shujiro, Oi, Keiji, Higo, Taiki, Takemoto, Masao, Suematsu, Nobuhiro, Eshima, Kenichi, Miyata, Kenji, Usui, Makoto, Sadamatsu, Kenji, Kadokami, Toshiaki, Hironaga, Kiyoshi, Ichi, Ikuyo, Todaka, Koji, Kishimoto, Junji, Tsutsui, Hiroyuki

“…Aim: Several clinical trials using intravascular ultrasound (IVUS) evaluation have demonstrated that intensive lipid-lowering therapy by statin or a…”
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Association of Serum Oxysterols with Cholesterol Metabolism Markers and Clinical Factors in Patients with Coronary Artery Disease: A Covariance Structure Analysis by Akiyama, Yusuke, Katsuki, Shunsuke, Matoba, Tetsuya, Nakano, Yasuhiro, Takase, Susumu, Nakashiro, Soichi, Yamamoto, Mitsutaka, Mukai, Yasushi, Inoue, Shujiro, Oi, Keiji, Higo, Taiki, Takemoto, Masao, Suematsu, Nobuhiro, Eshima, Kenichi, Miyata, Kenji, Usui, Makoto, Sadamatsu, Kenji, Kadokami, Toshiaki, Hironaga, Kiyoshi, Ichi, Ikuyo, Todaka, Koji, Kishimoto, Junji, Tsutsui, Hiroyuki

“…Oxysterols have been implicated in the pathogenesis of cardiovascular diseases. Serum levels of oxysterols could be positively correlated with cholesterol…”
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Dietary Oxysterol, 7-Ketocholesterol Accelerates Hepatic Lipid Accumulation and Macrophage Infiltration in Obese Mice by Chang, Jiuyang, Koseki, Masahiro, Saga, Ayami, Kanno, Kotaro, Higo, Tomoaki, Okuzaki, Daisuke, Okada, Takeshi, Inui, Hiroyasu, Tanaka, Katsunao, Asaji, Masumi, Zhu, Yinghong, Kamada, Yoshihiro, Ono, Masafumi, Saibara, Toshiji, Ichi, Ikuyo, Ohama, Tohru, Nishida, Makoto, Yamashita, Shizuya, Sakata, Yasushi

“…Non-alcoholic fatty liver disease is strongly associated with obese and type 2 diabetes. It has been reported that an oxidized cholesterol, 7-ketocholesterol…”
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Changes in the phospholipid fatty acid composition of the lipid droplet during the differentiation of 3T3-L1 adipocytes by Arisawa, Kotoko, Ichi, Ikuyo, Yasukawa, Yukiko, Sone, Yasuko, Fujiwara, Yoko

“…Lipid droplets (LDs) are independent organelles in adipocytes that are composed of a lipid ester core surrounded by a phospholipid monolayer. The fatty acid…”
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