Search Results - "Iceman, Kimberly E."

Sex-specific vagal and spinal modulation of swallow and its coordination with breathing by Huff, Alyssa, Reed, Mitchell D, Iceman, Kimberly E, Howland, Dena R, Pitts, Teresa

“…Swallow-breathing coordination is influenced by changes in lung volume, which is modulated by feedback from both vagal and spinal sensory afferents. The…”
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Sex-specific vagal and spinal modulation of breathing with chest compression by Huff, Alyssa, Reed, Mitchell D, Iceman, Kimberly E, Howland, Dena R, Pitts, Teresa

“…Lung volume is modulated by sensory afferent feedback via vagal and spinal pathways. The purpose of this study was to systematically alter afferent feedback…”
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Medullary serotonin neurons are CO2 sensitive in situ by Iceman, Kimberly E, Richerson, George B, Harris, Michael B

“…Brainstem central chemoreceptors are critical to the hypercapnic ventilatory response, but their location and identity are poorly understood. When studied in…”
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Differential effects of acute cerebellectomy on cough in spontaneously breathing cats by Musselwhite, M. Nicholas, Shen, Tabitha Y, Rose, Melanie J, Iceman, Kimberly E, Poliacek, Ivan, Pitts, Teresa, Bolser, Donald C

“…The role of the cerebellum in controlling the cough motor pattern is not well understood. We hypothesized that cerebellectomy would disinhibit motor drive to…”
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Rapid activation of esophageal mechanoreceptors alters the pharyngeal phase of swallow: Evidence for inspiratory activity during swallow by Frazure, Michael L, Brown, Alyssa D, Greene, Clinton L, Iceman, Kimberly E, Pitts, Teresa

“…Swallow is a complex behavior that consists of three coordinated phases: oral, pharyngeal, and esophageal. Esophageal distension (EDist) has been shown to…”
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Swallow Motor Pattern Is Modulated by Fixed or Stochastic Alterations in Afferent Feedback by King, Suzanne N, Shen, Tabitha Y, Musselwhite, M Nicholas, Huff, Alyssa, Reed, Mitchell D, Poliacek, Ivan, Howland, Dena R, Dixon, Warren, Morris, Kendall F, Bolser, Donald C, Iceman, Kimberly E, Pitts, Teresa

“…Afferent feedback can appreciably alter the pharyngeal phase of swallow. In order to measure the stability of the swallow motor pattern during several types of…”
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Deglutition and the Regulation of the Swallow Motor Pattern by Pitts, Teresa, Iceman, Kimberly E

“…Despite centuries of investigation, questions and controversies remain regarding the fundamental genesis and motor pattern of swallow. Two significant topics…”
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Functional connectivity in raphé-pontomedullary circuits supports active suppression of breathing during hypocapnic apnea by Nuding, Sarah C, Segers, Lauren S, Iceman, Kimberly E, O'Connor, Russell, Dean, Jay B, Bolser, Donald C, Baekey, David M, Dick, Thomas E, Shannon, Roger, Morris, Kendall F, Lindsey, Bruce G

“…Hyperventilation is a common feature of disordered breathing. Apnea ensues if CO2 drive is sufficiently reduced. We tested the hypothesis that medullary raphé,…”
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Laryngeal and swallow dysregulation following acute cervical spinal cord injury by Pitts, Teresa, Iceman, Kimberly E, Huff, Alyssa, Musselwhite, M Nicholas, Frazure, Michael L, Young, Kellyanna C, Greene, Clinton L, Howland, Dena R

“…Laryngeal function is vital to airway protection. Although swallow is mediated by the brainstem, the mechanism underlying the increased risk of dysphagia after…”
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Cough and swallow after laparotomy in anesthetized cats by Poliacek, Ivan, Martvon, Lukas, Simera, Michal, Veternik, Marcel, Misek, Jakub, Cibulkova, Lucia, Iceman, Kimberly E, Bolser, Donald C, Pitts, Teresa

“…An anesthetized cat animal model was used to evaluate changes in cough and swallow after a small midline upper abdominal incision (laparotomy). Two additional…”
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Hypoxia evokes a sequence of raphe-pontomedullary network operations for inspiratory drive amplification and gasping by Nuding, Sarah C, Segers, Lauren S, Iceman, Kimberly E, O'Connor, Russell, Dean, Jay B, Valarezo, Pierina A, Shuman, Dale, Solomon, Irene C, Bolser, Donald C, Morris, Kendall F, Lindsey, Bruce G

“…Hypoxia can trigger a sequence of breathing-related behaviors, from augmentation to apneusis to apnea and gasping. Gasping is an autoresuscitative behavior…”
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Dysphagia as a Missing Link Between Post-surgical- and Opioid-Related Pneumonia by Frazure, Michael, Greene, Clinton L., Iceman, Kimberly E., Howland, Dena R., Pitts, Teresa

“…Purpose Postoperative pneumonia remains a common complication of surgery, despite increased attention. The purpose of our study was to determine the effects of…”
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The laryngeal adductor reflex (LAR) is modulated by the serotonin 5-HT 1A agonist 8-OH-DPAT by Young, Kellyanna C, Musselwhite, M N, Frazure, Michael L, Greene, Clinton L, Iceman, Kimberly E, Pitts, Teresa

“…Airway protection is maintained through a constellation of behaviors. The laryngeal adductor reflex (LAR) responds to mechanical or chemical stimulation of the…”
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The 5-HT 1A Agonist 8-OH-DPAT Enhances Submental Laryngeal Elevator EMG Amplitude During Swallow by Musselwhite, M N, Young, Kellyanna C, Frazure, Michael L, Greene, Clinton L, Iceman, Kimberly E, Pitts, Teresa

“…Swallow is a critical behavior for sustaining life, important for both for the ingestion of nutrients and for protecting the airways. To produce an effective…”
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The influence of CO2 on spatiotemporal features of mechanically induced cough in anesthetized cats by Musselwhite, M. Nicholas, Shen, Tabitha Y., Rose, Melanie J., Iceman, Kimberly E., Poliacek, Ivan, Pitts, Teresa, Bolser, Donald C.

“…Effective cough requires a significant increase in lung volume used to produce the shear forces on the airway to clear aspirated material. This increase in…”
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The rostral medulla of bullfrog tadpoles contains critical lung rhythmogenic and chemosensitive regions across metamorphosis by Reed, Mitchell D., Iceman, Kimberly E., Harris, Michael B., Taylor, Barbara E.

“…The development of amphibian breathing provides insight into vertebrate respiratory control mechanisms. Neural oscillators in the rostral and caudal medulla…”
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Isoflurane abolishes spontaneous firing of serotonin neurons and masks their pH/CO₂ chemosensitivity by Massey, Cory A, Iceman, Kimberly E, Johansen, Sara L, Wu, Yuanming, Harris, Michael B, Richerson, George B

“…Serotonin (5-hydroxytryptamine, 5-HT) neurons from the mouse and rat rostral medulla are stimulated by increased CO2 when studied in culture or brain slices…”
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Buccal rhythmogenesis and CO2 sensitivity in Lithobates catesbeianus tadpole brainstems across metamorphosis by Reed, Mitchell D., Iceman, Kimberly E., Harris, Michael B., Taylor, Barbara E

“…•The midbrain/pons affects buccal burst shape and CO2 responsiveness in bullfrog tadpoles.•Buccal bursting can be responsive to elevated CO2, but only when the…”
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Carotid chemoreceptors tune breathing via multipath routing: reticular chain and loop operations supported by parallel spike train correlations by Morris, Kendall F, Nuding, Sarah C, Segers, Lauren S, Iceman, Kimberly E, O'Connor, Russell, Dean, Jay B, Ott, Mackenzie M, Alencar, Pierina A, Shuman, Dale, Horton, Kofi-Kermit, Taylor-Clark, Thomas E, Bolser, Donald C, Lindsey, Bruce G

“…We tested the hypothesis that carotid chemoreceptors tune breathing through parallel circuit paths that target distinct elements of an inspiratory neuron chain…”
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CO2 -inhibited neurons in the medullary raphé are GABAergic by Iceman, Kimberly E, Corcoran, Andrea E, Taylor, Barbara E, Harris, Michael B

“…Highlights • The medullary raphé contains neurons that are reversibly inhibited by CO2. • CO2 -inhibited raphé cells synthesize GABA, but not serotonin. • Fast…”
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