Search Results - "Ibrahim, Nashwa"

JNK inhibitor and ferroptosis modulator as possible therapeutic modalities in Alzheimer disease (AD) by Zakaria, Sherin, Ibrahim, Nashwa, Abdo, Walied, E. El-Sisi, Alaa

“…Alzheimer disease (AD) is among the most prevalent neurodegenerative diseases globally, marked by cognitive and behavioral disruptions. Ferroptosis is a form…”
Get full text

Discovery of new pyrimidopyrrolizine/indolizine-based derivatives as P-glycoprotein inhibitors: Design, synthesis, cytotoxicity, and MDR reversal activities by Shawky, Ahmed M., Abdalla, Ashraf N., Ibrahim, Nashwa A., Abourehab, Mohammed A.S., Gouda, Ahmed M.

“…Targeting P-glycoprotein (P-gp, ABCB1 transporter), which plays an essential role in multi-drug resistance (MDR) in cancers, with new cytotoxic agents is a…”
Get full text

Discovery and optimization of 2,3-diaryl-1,3-thiazolidin-4-one-based derivatives as potent and selective cytotoxic agents with anti-inflammatory activity by Shawky, Ahmed M, Almalki, Faisal A, Abdalla, Ashraf N, Youssif, Bahaa G M, Abdel-Fattah, Maha M, Hersi, Fatima, El-Sherief, Hany A M, Ibrahim, Nashwa A, Gouda, Ahmed M

“…Several studies have indicated the potential therapeutic outcomes of combining selective COX-2 inhibitors with tubulin-targeting anticancer agents. In the…”
Get full text

Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential cytotoxicity and CDK inhibitory activities by Shawky, Ahmed M., Ibrahim, Nashwa A., Abourehab, Mohammed A. S., Abdalla, Ashraf N., Gouda, Ahmed M.

“…In the current study, virtual screening of a small library of 1302 pyrrolizines bearing urea/thiourea moieties was performed. The top-scoring hits were…”
Get full text

Therapeutic potentials of mesenchymal stem cells in the treatment of inflammatory bowel disease in rats by Ali Mohammed, Shuzan, Elbaramawy, Azza, Hassan Abd‐Allah, Somia, Elkholy, Adel, Ibrahim Elsayed, Nashwa, Hussein, Samia

“…Interleukin‐1beta (IL‐1β) and interleukin‐17A (IL‐17A) have strong pro‐inflammatory activities that are involved in inflammatory bowel diseases (IBDs)…”
Get full text

Chemopreventive Potential of Myrtenal against Nitrosamine-Initiated, Radiation-Promoted Rat Bladder Carcinogenesis by Farrag, Mostafa A., Ezz, Magda K., Ibrahim, Nashwa K., Ahmed, Emad K.

“…The present study was undertaken to evaluate the chemopreventive activity of myrtenal, a natural monoterpene, against bladder carcinoma in rats induced with…”
Get full text

Posttraumatic growth and recovery among a sample of Egyptian mental health service users: a phenomenological study by Ibrahim, Nashwa, Ng, Fiona, Selim, Abeer, Ghallab, Eman, Ali, Amira, Slade, Mike

“…Delivery of recovery-oriented mental health practice is fundamental to personal recovery. Yet, there is lack of service users' accounts on what constitutes…”
Get full text

Post-traumatic growth in psychosis: a systematic review and narrative synthesis by Ng, Fiona, Ibrahim, Nashwa, Franklin, Donna, Jordan, Gerald, Lewandowski, Felix, Fang, Fan, Roe, David, Rennick-Egglestone, Stefan, Newby, Christopher, Hare-Duke, Laurie, Llewellyn-Beardsley, Joy, Yeo, Caroline, Slade, Mike

“…People with psychosis report experiences of highly traumatic events. Positive change or post-traumatic growth (PTG) can occur as a result of traumatic…”
Get full text

Novel pyrrolizines bearing 3,4,5-trimethoxyphenyl moiety: design, synthesis, molecular docking, and biological evaluation as potential multi-target cytotoxic agents by Shawky, Ahmed M., Ibrahim, Nashwa A., Abdalla, Ashraf N., Abourehab, Mohammed A. S., Gouda, Ahmed M.

“…In the present study, two new series of pyrrolizines bearing 3,4,5-trimethoxyphenyl moiety were designed, synthesised, and evaluated for their cytotoxic…”
Get full text

Covalent small-molecule inhibitors of SARS-CoV-2 Mpro: Insights into their design, classification, biological activity, and binding interactions by Shawky, Ahmed M., Almalki, Faisal A., Alzahrani, Hayat Ali, Abdalla, Ashraf N., Youssif, Bahaa G.M., Ibrahim, Nashwa A., Gamal, Mohammed, El-Sherief, Hany A.M., Abdel-Fattah, Maha M., Hefny, Ahmed A., Abdelazeem, Ahmed H., Gouda, Ahmed M.

“…Since 2020, many compounds have been investigated for their potential use in the treatment of SARS-CoV-2 infection. Among these agents, a huge number of…”
Get full text

Psychometric evaluation of the Depression Anxiety Stress Scale 8 among women with chronic non-cancer pelvic pain by Ali, Amira Mohammed, Hendawy, Amin Omar, Al-Amer, Rasmieh, Shahrour, Ghada, Ali, Esraa M., Alkhamees, Abdulmajeed A., Ibrahim, Nashwa, Lamadah, Sahar Mansour Taha, Ahmed, Afaf Hassan

“…Psychiatric comorbidity and abusive experiences in chronic pelvic pain (CPP) conditions may prolong disease course. This study investigated the psychometrics…”
Get full text

Experiences of peer support workers supporting individuals with substance use disorders in Egypt: phenomenological analysis by Ibrahim, Nashwa, Selim, Abeer, Ng, Fiona, Kasaby, Muhamed, Ali, Amira Mohammed, Eweida, Rasha, Almakki, Doha, Elaagib, Amna, Slade, Mike

“…Abstract Background Peer support work for substance use disorders is widely implemented in high-income countries. More research is still needed to understand…”
Get full text

The Implication of microRNAs as non-invasive biomarkers in 179 Egyptian breast cancer female patients by Shaaban, Nadia Z, Ibrahim, Nashwa K, Saada, Helen N, El-Rashidy, Fatma H, Shaaban, Hebatallah M, Elbakary, Nermeen M, Kodous, Ahmad S

“…MicroRNAs (miRs) are small (19-25 nucleotides), non-protein coding RNAs that regulate gene expression, and thus play essential roles in cell cycle progression…”
Get full text

Rutin Suppresses DMBA Carcinogenesis in the Breast Through Modulating IL-6/NF-κB, SRC1/HSP90 and ER-α by Youssef, Seham S M, Ibrahim, Nashwa K, El-Sonbaty, Sawsan M, El-Din Ezz, Magda K

“…Rutin dietary supplements may offer pharmacological benefits as anticancer and antiinflammatory properties. This study aimed to investigate the inhibitory and…”
Get full text

Psychological first aid intervention: rescue from psychological distress and improving the pre-licensure nursing students’ resilience amidst COVID-19 crisis and beyond by Eweida, Rasha Salah, Rashwan, Zohour Ibrahim, Khonji, Leena Mohammad, Shalhoub, Abdullah Abdulrahman Bin, Ibrahim, Nashwa

“…The public health emergencies such as the COVID-19 pandemic resulted in mental and psychological ramifications on the healthcare professionals. The…”
Get full text

Psychometric evaluation of the depression anxiety stress scale 8-items (DASS-8)/DASS-12/DASS-21 among family caregivers of patients with dementia by Ali, Amira Mohammed, Alameri, Rana Ali, Hendawy, Amin Omar, Al-Amer, Rasmieh, Shahrour, Ghada, Ali, Esraa M, Alkhamees, Abdulmajeed A, Ibrahim, Nashwa, Hassan, Bothaina Hussein

“…Patients with dementia express a set of problematic and deteriorating symptoms, along with self-care dependency. Over time, the mental health of family…”
Get full text

Design and Synthesis of Some 3-Substituted-2-[(2,4-dichlorophenoxy)-methyl]quinazolin-4(3H)-one Derivatives as Potential Anticonvulsant Agents by Abbas, Safinaz El-Sayed, Awadallah, Fadi Mohsen, Ibrahim, Nashwa Ahmed, Said, Eman Gaber, Kamel, Gihan

“…Series of 2,3-disubstituted quinazolinone derivatives and a [1,2,4]triazino[2,3-c]quinazolinone featuring the pharmacophoric elements of anticonvulsant drugs…”
Get full text

The Beneficial Radioprotective Effect of Tomato Seed Oil Against Gamma Radiation-Induced Damage in Male Rats by Ezz, Magda K., Ibrahim, Nashwa K., Said, Mahmoud M., Farrag, Mostafa A.

“…Radiation protection research receives intense focus due to its significant impact on human health. The present study was undertaken to investigate the…”
Get full text

Socio-economic and demographic factors associated with adaptive behaviour among children diagnosed with autism spectrum disorder in Egypt by Ibrahim, Nashwa, El-abdeen, Asmaa Maher Zein, Ng, Fiona, Zoromba, Mohamed, Haikal, Aml

“…Background Adaptive behaviour among children diagnosed with autism spectrum disorder determines wide range of self-independent and autonomous activities…”
Get full text

Novel substituted and fused pyrrolizine derivatives: Synthesis, anti-inflammatory and ulcerogenecity studies by ABBAS, Safinaz E, AWADALLAH, Fadi M, IBRAHIM, Nashwa A, GOUDA, Ahmed M

“…Synthesis of several substituted pyrrolizines 10a-f, 11a-f, 13a-c, pyrimidopyrrolizines 14a-c, 15a-c, and pyrrolizinopyrimidoisoindoles 12a-c was discussed…”
Get full text