Search Results - "Ibrahim, Ibrahim M"

GRP78: A cell's response to stress by Ibrahim, Ibrahim M., Abdelmalek, Doaa H., Elfiky, Abdo A.

“…Glucose-Regulated Protein 78 (GRP78) is a chaperone heat shock protein that has been intensely studied in the last two decades. GRP78 is the master of the…”
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Influence of α-Fe2O3, CuO and GO 2D nano-fillers on the structure, physical properties and antifungal activity of Na-CMC–PAAm blend by Abou Elfadl, A., Ibrahim, Asmaa M. M., El Sayed, Adel M., Saber, S., Elnaggar, Sameh, Ibrahim, Ibrahim M.

“…The present work aims to improve the uses of the carboxymethyl cellulose–polyacrylamide (Na-CMC–PAAm) blend for energy storage, optoelectronic applications,…”
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Computer-Aided Drug Design of Novel Derivatives of 2-Amino-7,9-dihydro-8H-purin-8-one as Potent Pan-Janus JAK3 Inhibitors by Faris, Abdelmoujoud, Ibrahim, Ibrahim M, Al Kamaly, Omkulthom, Saleh, Asmaa, Elhallaoui, Menana

“…Rheumatoid arthritis (RA) remains one of the most prevalent autoimmune diseases worldwide. Janus kinase 3 (JAK3) is an essential enzyme for treating autoimmune…”
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Design, Synthesis, Docking, DFT, MD Simulation Studies of a New Nicotinamide-Based Derivative: In Vitro Anticancer and VEGFR-2 Inhibitory Effects by Elkaeed, Eslam B., Yousef, Reda G., Elkady, Hazem, Gobaara, Ibraheem M. M., Alsfouk, Bshra A., Husein, Dalal Z., Ibrahim, Ibrahim M., Metwaly, Ahmed M., Eissa, Ibrahim H.

“…A nicotinamide-based derivative was designed as an antiproliferative VEGFR-2 inhibitor with the key pharmacophoric features needed to interact with the VEGFR-2…”
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Evaluation of synthesized biosurfactants as promising corrosion inhibitors and alternative antibacterial and antidermatophytes agents by Fawzy, Ahmed, Al Bahir, Areej, Alqarni, Nada, Toghan, Arafat, Khider, Manal, Ibrahim, Ibrahim M., Abulreesh, Hussein Hasan, Elbanna, Khaled

“…This study investigated different amino acid-based surfactants ( AASs ), also known as biosurfactants, including sodium N-dodecyl asparagine ( AS ), sodium…”
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The effect of ferulic acid against lead-induced oxidative stress and DNA damage in kidney and testes of rats by Kelainy, Eman G., Ibrahim Laila, Ibrahim M., Ibrahim, Shaimaa R.

“…Oxidative stress is an imbalance between free radicals and antioxidants which leads to reactive oxygen species (ROS) production in cells. Reactive oxygen…”
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New Anticancer Theobromine Derivative Targeting EGFRWT and EGFRT790M: Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies by Elkaeed, Eslam B., Yousef, Reda G., Elkady, Hazem, Alsfouk, Aisha A., Husein, Dalal Z., Ibrahim, Ibrahim M., Metwaly, Ahmed M., Eissa, Ibrahim H.

“…Based on the pharmacophoric features of EGFR inhibitors, a new semisynthetic theobromine-derived compound was designed to interact with the catalytic pocket of…”
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( E )- N -(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide: A Novel Pyridine Derivative for Inhibiting Vascular Endothelial Growth Factor Receptor-2: Synthesis, Computational, and Anticancer Studies by Yousef, Reda G, Elkady, Hazem, Elkaeed, Eslam B, Gobaara, Ibraheem M M, Al-Ghulikah, Hanan A, Husein, Dalal Z, Ibrahim, Ibrahim M, Metwaly, Ahmed M, Eissa, Ibrahim H

“…( )- -(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide (compound ) was designed as an antiangiogenic VEGFR-2 inhibitor with…”
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The ameliorating effect of Rutin on hepatotoxicity and inflammation induced by the daily administration of vortioxetine in rats by Anwar, Mai M, Laila, Ibrahim M Ibrahim

“…Vortioxetine (VORTX) is a potent and selective type of selective serotonin reuptake inhibitor (SSRI) that is mainly prescribed for treating major depression…”
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Hypertension in developing countries by Ibrahim, M Mohsen, Prof, Damasceno, Albertino, Prof

“…Summary Data from different national and regional surveys show that hypertension is common in developing countries, particularly in urban areas, and that rates…”
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Mitigative effect of caffeine against diclofenac-induced hepato-renal damage and chromosomal aberrations in male albino rats by Anwar, Mai M, Laila, Ibrahim M Ibrahim

“…Among the most commonly consumed non-steroidal anti-inflammatory drugs (NSAID) is Diclofenac (Dic), especially in low-income countries due to its high…”
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Common Variants of the Novel Type 2 Diabetes Genes CDKAL1 and HHEX/IDE Are Associated With Decreased Pancreatic β-Cell Function by Pascoe, Laura, Tura, Andrea, Patel, Sheila K, Ibrahim, Ibrahim M, Ferrannini, Ele, Zeggini, Eleftheria, Weedon, Michael N, Mari, Andrea, Hattersley, Andrew T, McCarthy, Mark I, Frayling, Timothy M, Walker, Mark

“…Common Variants of the Novel Type 2 Diabetes Genes CDKAL1 and HHEX/IDE Are Associated With Decreased Pancreatic β-Cell Function Laura Pascoe 1 , Andrea Tura 2…”
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A Review of Human Coronaviruses’ Receptors: The Host-Cell Targets for the Crown Bearing Viruses by Nassar, Aaya, Ibrahim, Ibrahim M., Amin, Fatma G., Magdy, Merna, Elgharib, Ahmed M., Azzam, Eman B., Nasser, Filopateer, Yousry, Kirllos, Shamkh, Israa M., Mahdy, Samah M., Elfiky, Abdo A.

“…A novel human coronavirus prompted considerable worry at the end of the year 2019. Now, it represents a significant global health and economic burden. The…”
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Advances in Polysaccharide-Based Oral Colon-Targeted Delivery Systems: The Journey So Far and the Road Ahead by Ibrahim, Ibrahim M

“…Various colon-targeted oral delivery systems have been explored so far to treat colorectal diseases, including timed-release systems, prodrugs, pH-based…”
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Polyhydroxyalkanoates: Characteristics, production, recent developments and applications by Raza, Zulfiqar Ali, Abid, Sharjeel, Banat, Ibrahim M.

“…Polyhydroxyalkanoates (PHAs) are biopolyesters, stored within cells as energy storage materials by various microorganisms. Due to their biocompatibility and…”
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Cilostazol attenuates mirabegron-induced hepatic and renal toxicity in rats: regulation of metabolic, oxidative, and inflammatory pathways by Anwar, Mai M, Ibrahim Laila, Ibrahim M

“…Mirabegron (MIRG) is a type of β3 adrenoceptor agonist that is considered an alternative therapy for the treatment of overactive bladder (OAB) symptoms…”
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Novel sofosbuvir derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective by Alrehaily, Abdulwahed, Elfiky, Abdo A., Ibrahim, Ibrahim M., Ibrahim, Mohamed N., Sonousi, Amr

“…The human coronavirus, SARS-CoV-2, had a negative impact on both the economy and human health, and the emerging resistant variants are an ongoing threat. One…”
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Caffeic acid derivatives (CAFDs) as inhibitors of SARS-CoV-2: CAFDs-based functional foods as a potential alternative approach to combat COVID-19 by Adem, Şevki, Eyupoglu, Volkan, Sarfraz, Iqra, Rasul, Azhar, Zahoor, Ameer Fawad, Ali, Muhammad, Abdalla, Mohnad, Ibrahim, Ibrahim M, Elfiky, Abdo A

“…SARS-CoV-2, an emerging strain of coronavirus, has affected millions of people from all the continents of world and received worldwide attention. This emerging…”
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Targeting SARS-CoV-2 endoribonuclease: a structure-based virtual screening supported by in vitro analysis by Ibrahim, Ibrahim M., Elfiky, Abdo A., Fathy, Mohamed M., Mahmoud, Sara H., ElHefnawi, Mahmoud

“…Researchers are focused on discovering compounds that can interfere with the COVID-19 life cycle. One of the important non-structural proteins is…”
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Glycogen and its related enzymes of metabolism in the central nervous system by Ibrahim, M Z

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