Search Results - "Iborra‐Lázaro, Guillermo"

Hippocampal long‐term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing G‐protein‐gated inwardly rectifying potassium channel activity by Sánchez‐Rodríguez, Irene, Djebari, Souhail, Temprano‐Carazo, Sara, Vega‐Avelaira, David, Jiménez‐Herrera, Raquel, Iborra‐Lázaro, Guillermo, Yajeya, Javier, Jiménez‐Díaz, Lydia, Navarro‐López, Juan D.

“…Hippocampal synaptic plasticity disruption by amyloid‐β (Aβ) peptides + thought to be responsible for learning and memory impairments in Alzheimer's disease…”
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CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative and non‐associative learning by Iborra‐Lázaro, Guillermo, Djebari, Souhail, Sánchez‐Rodríguez, Irene, Gratacòs‐Batlle, Esther, Sánchez‐Fernández, Nuria, Radošević, Marija, Casals, Núria, Navarro‐López, Juan de Dios, Soto del Cerro, David, Jiménez‐Díaz, Lydia

“…Carnitine palmitoyltransferase 1c (CPT1C) is a neuron‐specific protein widely distributed throughout the CNS and highly expressed in discrete brain areas…”
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Systematic characterization of a non-transgenic Aβ 1–42 amyloidosis model: synaptic plasticity and memory deficits in female and male mice by Raquel Jiménez-Herrera, Ana Contreras, Souhail Djebari, Jaime Mulero-Franco, Guillermo Iborra-Lázaro, Danko Jeremic, Juan Navarro-López, Lydia Jiménez-Díaz

“…Abstract Background The amyloid-β (Aβ) cascade is one of the most studied theories linked to AD. In multiple models, Aβ accumulation and dyshomeostasis have…”
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SIGMA-1 RECEPTOR ACTIVATION PRESERVES HIPPOCAMPAL SYNAPTIC PLASTICITY AND HIPPOCAMPAL-DEPENDENT CONTEXTUAL AND SOCIAL MEMORY IN AN EARLY AMYLOIDOPATHY MOUSE MODEL by Djebari, Souhail, Jiménez-Hererra, Raquel, Iborra-Lázaro, Guillermo, Jiménez-Díaz, Lydia, Navarro-López, Juan D.

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SYSTEMATIC CHARACTERIZATION OF A NON-TRANSGENIC AΒ1–42 AMYLOIDOSIS MODEL: SYNAPTIC PLASTICITY AND MEMORY DEFICITS IN FEMALE AND MALE MICE by Jiménez-Hererra, Raquel, Contreras, Ana, Iborra-Lázaro, Guillermo, Jeremic, Danko, Djebari, Souhail, Navarro-López, Juan D., Jiménez-Díaz, Lydia

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VU0810464, A GIRK CHANNEL ACTIVATOR, COUNTERACTS SYNAPTIC PLASTICITY AND VISUO-SPATIAL MEMORY IMPAIRMENTS IN AN EARLY AMYLOIDOPATHY MOUSE MODEL by Franco, Jaime Mulero, Jiménez-Herrera, Raquel, Contreras, Ana, Djebari, Souhail, Iborra-Lázaro, Guillermo, Jiménez-Díaz, Lydia, Navarro-López, Juan D.

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NEW INSIGHTS INTO CPT1C FUNCTIONS RELATED TO LEARNING AND MEMORY: FROM SYNAPSES TO BEHAVIOR by Lázaro, Guillermo Iborra, Djebari, Souhail, Sánchez-Rodríguez, Irene, Gratacòs-Batlle, Esther, Sánchez-Fernández, Nuria, Radosevic, Marija, Casals, Nuria, Navarro-López, Juan D., Soto, David, Jiménez-Díaz, Lydia

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Impairments of Synaptic Plasticity Induction Threshold and Network Oscillatory Activity in the Hippocampus Underlie Memory Deficits in a Non-Transgenic Mouse Model of Amyloidosis by Mayordomo-Cava, Jennifer, Iborra-Lazaro, Guillermo, Djebari, Souhail, Temprano- Carazo, Sara, Sanchez-Rodriguez, Irene, Jeremic, Danko, Gruart, Agnes, Delgado-Garda, Jose Maria, Jimenez-Diaz, Lydia, Navarro-Lopez, Juan D

“…In early Alzheimer disease (AD) models synaptic failures and upstreaming aberrant patterns of network synchronous activity result in hippocampal-dependent…”
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G-Protein-Gated Inwardly Rectifying Potassium (Kir3/GIRK) Channels Govern Synaptic Plasticity That Supports Hippocampal-Dependent Cognitive Functions in Male Mice by Djebari, Souhail, Iborra-Lázaro, Guillermo, Temprano-Carazo, Sara, Sánchez-Rodríguez, Irene, Nava-Mesa, Mauricio O, Múnera, Alejandro, Gruart, Agnès, Delgado-García, José M, Jiménez-Díaz, Lydia, Navarro-López, Juan D

“…The G-protein-gated inwardly rectifying potassium (Kir3/GIRK) channel is the effector of many G-protein-coupled receptors (GPCRs). Its dysfunction has been…”
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Altered Balance of Reelin Proteolytic Fragments in the Cerebrospinal Fluid of Alzheimer's Disease Patients by Lopez-Font, Inmaculada, Lennol, Matthew P, Iborra-Lazaro, Guillermo, Zetterberg, Henrik, Blennow, Kaj, Sáez-Valero, Javier

“…Reelin binds to the apolipoprotein E receptor apoER2 to activate an intracellular signaling cascade. The proteolytic cleavage of reelin follows receptor…”
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Systematic characterization of a non-transgenic Aβ1–42 amyloidosis model: synaptic plasticity and memory deficits in female and male mice by Jiménez-Herrera, Raquel, Contreras, Ana, Djebari, Souhail, Mulero-Franco, Jaime, Iborra-Lázaro, Guillermo, Jeremic, Danko, Navarro-López, Juan, Jiménez-Díaz, Lydia

“…Abstract Background The amyloid- β (A β ) cascade is one of the most studied theories linked to AD. In multiple models, A β accumulation and dyshomeostasis…”
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Systematic characterization of a non-transgenic A[beta]1-42 amyloidosis model: synaptic plasticity and memory deficits in female and male mice by Jiménez-Herrera, Raquel, Contreras, Ana, Djebari, Souhail, Mulero-Franco, Jaime, Iborra-Lázaro, Guillermo, Jeremic, Danko, Navarro-López, Juan, Jiménez-Díaz, Lydia

“…Background The amyloid-[beta] (A[beta]) cascade is one of the most studied theories linked to AD. In multiple models, A[beta] accumulation and dyshomeostasis…”
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Long‐term synaptic depression and memory deficits are reversed by enhancement of GirK‐dependent signaling in a mouse model of early amyloidopathy by Jimenez‐Diaz, Lydia, Sanchez‐Rodriguez, Irene, Djebari, Souhail, Temprano‐Carazo, Sara, Yajeya, Javier, Iborra‐Lázaro, Guillermo, Vega, David, Jimenez, Raquel, Navarro‐Lopez, Juan D.

“…Background Hippocampal synaptic plasticity disruption by amyloid‐β (Aβ) peptides is thought to be responsible for learning and memory impairments in…”
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Characterization of hippocampal amyloidosis induced by amyloid‐ β in behaving mice: Developing topics by Iborra‐Lázaro, Guillermo, Mayordomo‐Cava, Jennifer, Sánchez‐Rodríguez, Irene, Temprano‐Carazo, Sara, Djebari, Souhail, Gruart, Agnès, Delgado‐Garcia, Jose Maria, Navarro‐López, Juan D., Jimenez‐Diaz, Lydia

“…Abstract Background In early stages of Alzheimer’s disease, disruption of learning and memory processes that rely on hippocampal performance correlates with…”
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Characterization of hippocampal amyloidosis induced by amyloid‐β in behaving mice by Iborra‐Lázaro, Guillermo, Mayordomo‐Cava, Jennifer, Sánchez‐Rodríguez, Irene, Temprano‐Carazo, Sara, Djebari, Souhail, Gruart, Agnès, Delgado‐Garcia, Jose Maria, Navarro‐López, Juan D., Jimenez‐Diaz, Lydia

“…Background In early stages of Alzheimer’s disease, disruption of learning and memory processes that rely on hippocampal performance correlates with aberrant…”
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Long‐term synaptic depression and memory deficits are reversed by enhancement of GirK‐dependent signaling in a mouse model of early amyloidopathy: Molecular and cell biology/synaptic disruption by Jimenez‐Diaz, Lydia, Sanchez‐Rodriguez, Irene, Djebari, Souhail, Temprano‐Carazo, Sara, Yajeya, Javier, Iborra‐Lázaro, Guillermo, Vega, David, Jimenez, Raquel, Navarro‐Lopez, Juan D.

“…Abstract Background Hippocampal synaptic plasticity disruption by amyloid‐ β (A β ) peptides is thought to be responsible for learning and memory impairments…”
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CSF-ApoER2 fragments as a read-out of reelin signaling: Distinct patterns in sporadic and autosomal-dominant Alzheimer disease by Lopez-Font, Inmaculada, Iborra-Lazaro, Guillermo, Sánchez-Valle, Raquel, Molinuevo, José-Luis, Cuchillo-Ibañez, Inmaculada, Sáez-Valero, Javier

“…Reelin is a glycoprotein associated with synaptic plasticity and neurotransmission. The malfunctioning of reelin signaling in the brain is likely to contribute…”
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