Search Results - "Ibdah, Jamal A"

Mitochondrial Dysfunction Plays Central Role in Nonalcoholic Fatty Liver Disease by Ramanathan, Raghu, Ali, Ahmad Hassan, Ibdah, Jamal A.

“…Nonalcoholic fatty liver disease (NAFLD) is a global pandemic that affects one-quarter of the world’s population. NAFLD includes a spectrum of progressive…”
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Sirtuins and nonalcoholic fatty liver disease by Nassir, Fatiha, Ibdah, Jamal A

“…Mammalian sirtuins are seven members belonging to the silent information regulator 2 family, a group of Class Ⅲ histone/protein deacetylases. Sirtuins(SIRT…”
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Role of mitochondria in nonalcoholic fatty liver disease by Nassir, Fatiha, Ibdah, Jamal A

“…Nonalcoholic fatty liver disease (NAFLD) affects about 30% of the general population in the United States and includes a spectrum of disease that includes…”
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Characteristics of gastric cancer in Asia by Rahman, Rubayat, Asombang, Akwi W, Ibdah, Jamal A

“…Gastric cancer(GC)is the fourth most common cancer in the world with more than 70%of cases occur in the developing world.More than 50%of cases occur in Eastern…”
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Role of mitochondria in alcoholic liver disease by Nassir, Fatiha, Ibdah, Jamal A

“…Alcohol abuse is the leading cause of liver related morbidity and mortality.Chronic or binge alcohol drinking causes hepatic steatosis which can develop to…”
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Mitochondrial Dysfunction and Acute Fatty Liver of Pregnancy by Ramanathan, Raghu, Ibdah, Jamal A

“…The liver is one of the richest organs in mitochondria, serving as a hub for key metabolic pathways such as β-oxidation, the tricarboxylic acid (TCA) cycle,…”
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Compromised hepatic mitochondrial fatty acid oxidation and reduced markers of mitochondrial turnover in human NAFLD by Moore, Mary P., Cunningham, Rory P., Meers, Grace M., Johnson, Sarah A., Wheeler, Andrew A., Ganga, Rama R., Spencer, Nicole M., Pitt, James B., Diaz‐Arias, Alberto, Swi, Ahmed I. A., Hammoud, Ghassan M., Ibdah, Jamal A., Parks, Elizabeth J., Rector, R. Scott

“…Background and Aims NAFLD and its more‐advanced form, steatohepatitis (NASH), is associated with obesity and is an independent risk factor for cardiovascular,…”
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Role of 3-Hydroxy Fatty Acid-Induced Hepatic Lipotoxicity in Acute Fatty Liver of Pregnancy by Natarajan, Sathish Kumar, Ibdah, Jamal A

“…Acute fatty liver of pregnancy (AFLP), a catastrophic illness for both the mother and the unborn offspring, develops in the last trimester of pregnancy with…”
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Energy-matched moderate and high intensity exercise training improves nonalcoholic fatty liver disease risk independent of changes in body mass or abdominal adiposity — A randomized trial by Winn, Nathan C., Liu, Ying, Rector, R. Scott, Parks, Elizabeth J., Ibdah, Jamal A., Kanaley, Jill A.

“…Exercise training is commonly prescribed for individuals diagnosed with nonalcoholic fatty liver disease (NAFLD); however, consensus regarding the volume and…”
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Acute fatty liver of pregnancy： An update on pathogenesis and clinical implications by Ibdah, Jamal-A

“…Acute fatty liver of pregnancy （AFLP） is a serious maternal illness occurring in the third trimester of pregnancy with significant perinatal and maternal…”
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Staging accuracy of esophageal cancer by endoscopic ultrasound：A meta-analysis and systematic review by Puli, Srinivas-R, Reddy, Jyotsna-Bk, Bechtold, Matthew-L, Antillon, Daphne, Ibdah, Jamal-A, Antillon, Mainor-R

“…AIM： To evaluate the accuracy of endoscopic ultrasound （EUS） in the staging of esophageal cancer. METHODS： Only EUS studies confirmed by surgery were selected…”
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Nonalcoholic fatty liver disease and mitochondrial dysfunction by Wei, Yongzhong, Rector, R Scott, Thyfault, John P, Ibdah, Jamal A

“…Nonalcoholic fatty liver disease （NAFLD） includes hepatic steatosis, nonalcoholic steatohepatitis （NASH）, fibrosis, and cirrhosis. NAFLD is the most common…”
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Non-alcoholic fatty liver disease and the metabolic syndrome： An update by Rector, R Scott, Thyfault, John P, Wei, Yongzhong, Ibdah, Jamal A

“…Sedentary lifestyle and poor dietary choices are leading to a weight gain epidemic in westernized countries, subsequently increasing the risk for developing…”
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Regulation of mitochondrial trifunctional protein modulates nonalcoholic fatty liver disease in mice by Nassir, Fatiha, Arndt, Justin J., Johnson, Sarah A., Ibdah, Jamal A.

“…Mitochondrial trifunctional protein (MTP) plays a critical role in the oxidation of long-chain fatty acids. We previously reported that aging mice (>9 months…”
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Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model by Rector, R. Scott, Thyfault, John P, Uptergrove, Grace M, Morris, E. Matthew, Naples, Scott P, Borengasser, Sarah J, Mikus, Catherine R, Laye, Matthew J, Laughlin, M. Harold, Booth, Frank W, Ibdah, Jamal A

“…Background & Aims In this study, we sought to determine the temporal relationship between hepatic mitochondrial dysfunction, hepatic steatosis and insulin…”
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Critical Role for Hepatocyte-Specific eNOS in NAFLD and NASH by Cunningham, Rory P, Moore, Mary P, Dashek, Ryan J, Meers, Grace M, Takahashi, Takamune, Sheldon, Ryan D, Wheeler, Andrew A, Diaz-Arias, Alberto, Ibdah, Jamal A, Parks, Elizabeth J, Thyfault, John P, Rector, R Scott

“…Regulation of endothelial nitric oxide synthase (eNOS) in hepatocytes may be an important target in nonalcoholic fatty liver disease (NAFLD) development and…”
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eNOS deletion impairs mitochondrial quality control and exacerbates Western diet-induced NASH by Sheldon, Ryan D, Meers, Grace M, Morris, E Matthew, Linden, Melissa A, Cunningham, Rory P, Ibdah, Jamal A, Thyfault, John P, Laughlin, M Harold, Rector, R Scott

“…Dysregulated mitochondrial quality control leads to mitochondrial functional impairments that are central to the development and progression of hepatic…”
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Hepatocellular Carcinoma: The Role of MicroRNAs by Khare, Sharad, Khare, Tripti, Ramanathan, Raghu, Ibdah, Jamal A

“…Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. HCC is diagnosed in its advanced stage when limited treatment…”
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Thyroid Hormone and Mitochondrial Dysfunction: Therapeutic Implications for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) by Ramanathan, Raghu, Patwa, Sohum A, Ali, Ahmad Hassan, Ibdah, Jamal A

“…Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly termed nonalcoholic fatty liver disease (NAFLD), is a widespread global health…”
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Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats by Rector, R Scott, Thyfault, John P, Morris, R Tyler, Laye, Matthew J, Borengasser, Sarah J, Booth, Frank W, Ibdah, Jamal A

“…Exercise training is commonly prescribed for treatment of nonalcoholic fatty liver disease (NAFLD). We sought to determine whether exercise training prevents…”
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